Results 31 to 40 of about 10,728 (217)
Novel Insight Into Glycosaminoglycan Biosynthesis Based on Gene Expression Profiles
Frontiers in Cell and Developmental Biology, 2021 Glycosaminoglycans (GAGs) including chondroitin sulfate, dermatan sulfate, heparan sulfate, and keratan sulfate, except for hyaluronan that is a free polysaccharide, are covalently attached to core proteins to form proteoglycans.
Yi-Fan Huang +2 more
doaj +1 more source
Establishment of Glycosaminoglycan Assays for Mucopolysaccharidoses
Metabolites, 2014 Mucopolysaccharidoses (MPS) are a group of lysosomal storage disorders caused by deficiency of the lysosomal enzymes essential for catabolism of glycosaminoglycans (GAGs).
Shunji Tomatsu +13 more
doaj +1 more source
Proton conductivity of glycosaminoglycans.
PLoS ONE, 2019 Proton conductivity is important in many natural phenomena including oxidative phosphorylation in mitochondria and archaea, uncoupling membrane potentials by the antibiotic Gramicidin, and proton actuated bioluminescence in dinoflagellate.
John Selberg, Manping Jia, Marco Rolandi
doaj +1 more source
Collagens and proteoglycans of the corneal extracellular matrix
Brazilian Journal of Medical and Biological Research, 2003 The cornea is a curved and transparent structure that provides the initial focusing of a light image into the eye. It consists of a central stroma that constitutes 90% of the corneal depth, covered anteriorly with epithelium and posteriorly with ...
Y.M. Michelacci
doaj +1 more source
Orthopedic management of the extremities in patients with Morquio A syndrome. [PDF]
, 2014 BackgroundMusculoskeletal involvement in Morquio A syndrome (mucopolysaccharidosis IVA; MPS IVA) contributes significantly to morbidity and mortality. While the spinal manifestations of the disorder have received considerable attention in the literature,
Bache, C Edward +6 more
core +1 more source
Sulodexide. Nephroprotective properties and horizons for use in nephrology
Медицинский совет, 2015 Sulodexide belongs to the class of glycosaminoglycans (GAGs) or mucopolysaccharides. Found in mammalian tissuesm, GAGs regulate the activity of a wide range of proteins (including chemokines, cytokines, growth factors, enzymes, morphogens, and adhesion ...
M. M. Batyushin
doaj +1 more source
Safety and physiological effects of two different doses of elosulfase alfa in patients with morquio a syndrome: A randomized, double-blind, pilot study. [PDF]
, 2015 The primary treatment outcomes of a phase 2, randomized, double-blind, pilot study evaluating safety, physiological, and pharmacological effects of elosulfase alfa in patients with Morquio A syndrome are herewith presented.
Berger, Kenneth I +14 more
core +1 more source
Bio-Protocol, 2017 Chondroitin sulfate (CS), a member of the glycosaminoglycan (GAG) family of carbohydrates, is composed of linear, sulfated repeating disaccharide sequences of N-acetyl-D-galactosamine (GalNAc) and glucuronic acid (GlcA).
Kyohei Higashi, Toshihiko Toida
doaj +1 more source
Journal of Craniovertebral Junction and Spine, 2020 Morquio syndrome (MS) is an autosomal recessive defect caused by the deficiency of N-acetylgalactosamine-6-sulfatase. Odontoid hypoplasia, periodontoid soft tissue deposition, and cervical stenosis lead to myelopathy and quadriparesis in these patients ...
Suyash Singh +4 more
doaj +1 more source
Damage in porous media due to salt crystallization [PDF]
Physical Review E: Statistical, Nonlinear, and Soft Matter Physics
81 (2010) 066110, 2010 We investigate the origins of salt damage in sandstones for the two most common salts: sodium chloride and sulfate. The results show that the observed difference in damage between the two salts is directly related to the kinetics of crystallization and the interfacial properties of the salt solutions and crystals with respect to the stone. We show that,
arxiv +1 more source