Results 71 to 80 of about 410,791 (266)

Mucin-like glycopolymer gels in electrosensory tissues generate cues which direct electrolocation in amphibians and neuronal activation in mammals

open access: yesNeural Regeneration Research, 2019
Mucin-like glycoproteins have established roles in epithelial boundary protection and lubricative roles in some tissues. This mini-review illustrates alternative functional roles which rely on keratan sulphate and sialic acid modifications to mucin ...
James Melrose
doaj   +1 more source

Spatial and temporal changes in the distribution of proteoglycans during avian neural crest development [PDF]

open access: yes, 1991
In this study, we describe the distribution of various classes of proteoglycans and their potential matrix ligand, hyaluronan, during neural crest development in the trunk region of the chicken embryo.
Bronner-Fraser, Marianne   +5 more
core  

Resistance of corneal RFUVA-cross-linked collagens and small leucine-rich proteoglycans to degradation by matrix metalloproteinases [PDF]

open access: yes, 2013
Purpose. Extracellular matrix metalloproteinases (MMPs) are thought to play a crucial role in corneal degradation associated with the pathological progression of keratoconus.
Conrad, Gary W.   +4 more
core   +2 more sources

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

open access: yesAdvanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana   +2 more
wiley   +1 more source

A Novel Sprayable Fibrinogen/Glycosaminoglycans/Collagen‐Based Bioink for Skin Wound Healing Applied by a Handheld Dual‐Head Airbrush

open access: yesAdvanced Healthcare Materials, EarlyView.
A dual‐head airbrush‐based spraying device, combined with a fibrinogen bioink enriched with glycosaminoglycans and collagen, enables the delivery of biomaterials and cells to promote wound healing. This system demonstrates effective skin regeneration in vitro and in vivo, with comparable results to autografts.
Paula Pleguezuelos‐Beltrán   +7 more
wiley   +1 more source

Axonal pathfinding during the development of the nervous system

open access: yesAnnals of the Child Neurology Society, 2023
Guidance of axons sprouting from maturing neuroblasts, during intermediate trajectories and in seeking target neurons for synaptogenesis, is a fundamental developmental process in central nervous system maturation.
Harvey B. Sarnat
doaj   +1 more source

Safety and physiological effects of two different doses of elosulfase alfa in patients with morquio a syndrome: A randomized, double-blind, pilot study. [PDF]

open access: yes, 2015
The primary treatment outcomes of a phase 2, randomized, double-blind, pilot study evaluating safety, physiological, and pharmacological effects of elosulfase alfa in patients with Morquio A syndrome are herewith presented.
Berger, Kenneth I   +14 more
core   +1 more source

Synovial Fluid‐derived Micrococcus Luteus G18 Exacerbates Osteoarthritis Progression by Promoting Chondrocyte Degradation via TLR2/JNK/AP‐1 Signaling Pathway

open access: yesAdvanced Science, EarlyView.
Traditionally considered sterile, the articular cavity is now recognized to harbor microbial communities influencing osteoarthritis (OA). Integrating 16S rRNA sequencing and culturomics, Micrococcus luteus is enriched in advanced OA. Notably, M. luteus G18 exacerbates cartilage degeneration via TLR2/JNK/AP‐1‐mediated ECM disruption, revealing intra ...
Tingtao Chen   +6 more
wiley   +1 more source

GAG-DB, the New Interface of the Three-Dimensional Landscape of Glycosaminoglycans

open access: yesBiomolecules, 2020
Glycosaminoglycans (GAGs) are complex linear polysaccharides. GAG-DB is a curated database that classifies the three-dimensional features of the six mammalian GAGs (chondroitin sulfate, dermatan sulfate, heparin, heparan sulfate, hyaluronan, and keratan ...
Serge Pérez   +5 more
doaj   +1 more source

Increased migratory activity and cartilage regeneration by superficial-zone chondrocytes in enzymatically treated cartilage explants

open access: yesBMC Musculoskeletal Disorders, 2022
Background Limited chondrocyte migration and impaired cartilage-to-cartilage healing is a barrier in cartilage regenerative therapy. Collagenase treatment and delivery of a chemotactic agent may play a positive role in chondrocyte repopulation at the ...
Yuichiro Shiromoto   +9 more
doaj   +1 more source

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