Results 31 to 40 of about 182,642 (309)

Advances in keratinocyte delivery in burn wound care

Advanced Drug Delivery Reviews, 2018
This review gives an updated overview on keratinocyte transplantation in burn wounds concentrating on application methods and future therapeutic cell delivery options with a special interest in hydrogels and spray devices for cell delivery.
B. ter Horst, G. Chouhan, N. Moiemen, L. Grover   +3 more
semanticscholar   +1 more source

Vimentin coordinates fibroblast proliferation and keratinocyte differentiation in wound healing via TGF-β–Slug signaling

Proceedings of the National Academy of Sciences of the United States of America, 2016
Significance The central concept in this study is that a major cytoskeletal component, vimentin, acts as a signal integrator during wound healing, operating in both signal-triggering and signal-receiving cells. This is a previously unreported concept for
Fang Cheng, Yue-ming Shen, P. Mohanasundaram, M. Lindström, J. Ivaska, T. Ny, J. Eriksson   +6 more
semanticscholar   +1 more source

Interplay Between Keratinocytes and Fibroblasts: A Systematic Review Providing a New Angle for Understanding Skin Fibrotic Disorders

Frontiers in Immunology, 2020
Background/Objective: Skin fibrosis is the result of aberrant processes leading to abnormal deposition of extracellular matrix (ECM) in the dermis. In healthy skin, keratinocytes participate to maintain skin homeostasis by actively crosstalking with ...
Barbara Russo, Nicolò C. Brembilla, Nicolò C. Brembilla, Carlo Chizzolini   +3 more
doaj   +1 more source

The Protective Effect of Hamamelis virginiana Stem and Leaf Extract on Fine Dust-Induced Damage on Human Keratinocytes

Cosmetics, 2021
Witch hazel extracts have been used for decades as cosmetic ingredients in skin care products. Our present study aims to evaluate its potential in anti-pollution products using a previously reported in vitro model. Calcium is a universal second messenger,
Jiyoung Choi, Dongki Yang, Mi Yeon Moon, Gi Yeon Han, Moon Sik Chang, Joonseok Cha   +5 more
doaj   +1 more source

Living with Keratinocytes [PDF]

Stem Cell Reports, 2018
A feature distinguishing human hematopoietic and epithelial stem cells from other equally fascinating stem cells is perhaps their easier translation into a clinical setting. We have devoted nearly our entire scientific career in trying to turn our understanding of epithelial stem cell biology into something that could help people suffering from ...
Pellegrini, Graziella, De Luca, Michele
openaire   +3 more sources

Keratinocyte Carcinomas: Current Concepts and Future Research Priorities

Clinical Cancer Research, 2018
Cutaneous squamous cell carcinoma (cSCC) and basal cell carcinoma (BCC) are keratinocyte carcinomas, the most frequently diagnosed cancers in fair-skinned populations.
P. Nagarajan, M. Asgari, A. Green, S. Guhan, S. Arron, C. Proby, D. Rollison, C. Harwood, A. Toland   +8 more
semanticscholar   +1 more source

Keratin 14-dependent disulfides regulate epidermal homeostasis and barrier function via 14-3-3σ and YAP1

eLife, 2020
The intermediate filament protein keratin 14 (K14) provides vital structural support in basal keratinocytes of epidermis. Recent studies evidenced a role for K14-dependent disulfide bonding in the organization and dynamics of keratin IFs in skin ...
Yajuan Guo, Catherine J Redmond, Krystynne A Leacock, Margarita V Brovkina, Suyun Ji, Vinod Jaskula-Ranga, Pierre A Coulombe   +6 more
doaj   +1 more source

The human CIB1–EVER1–EVER2 complex governs keratinocyte-intrinsic immunity to β-papillomaviruses

Journal of Experimental Medicine, 2018
Patients with epidermodysplasia verruciformis (EV) and biallelic null mutations of TMC6 (encoding EVER1) or TMC8 (EVER2) are selectively prone to disseminated skin lesions due to keratinocyte-tropic human &bgr;-papillomaviruses (&bgr;-HPVs), which lack ...
S. D. de Jong, Amandine Créquer, I. Matos, David Hum, V. Gunasekharan, Lazaro Lorenzo, F. Jabot-Hanin, E. Imahorn, A. Arias, H. Vahidnezhad, L. Youssefian, J. Markle, E. Patin, Aurelia D’Amico, Claire Q. F. Wang, F. Full, A. Ensser, T. Leisner, L. Parise, M. Bouaziz, Nataly Portilla Maya, X. R. Cadena, B. Saka, A. Saeidian, N. Aghazadeh, S. Zeinali, P. Itin, J. Krueger, L. Laimins, L. Abel, E. Fuchs, J. Uitto, J. Franco, B. Burger, G. Orth, E. Jouanguy, J. Casanova   +36 more
semanticscholar   +1 more source

GJB4 variants linked to skin disease exhibit a trafficking deficiency en route to gap junction formation that can be restored by co-expression of select connexins

Frontiers in Cell and Developmental Biology, 2023
Epidermal keratinocytes are enriched with at least nine connexins that are key regulators of epidermal homeostasis. The role of Cx30.3 in keratinocytes and epidermal health became evident when fourteen autosomal dominant mutations in the Cx30.3-encoding ...
Sergiu A. Lucaciu, Sergiu A. Lucaciu, Rhett Figliuzzi, Ruth Neumann, Samina Nazarali, Luigi Del Sordo, Luigi Del Sordo, Stephanie E. Leighton, Alexandra Hauser, Qing Shao, Danielle Johnston, Donglin Bai, Dale W. Laird, Dale W. Laird   +13 more
doaj   +1 more source

Keratinocyte Growth Factor Promotes Melanosome Transfer to Keratinocytes [PDF]

Journal of Investigative Dermatology, 2005
Melanogenesis and melanosome transfer from the melanocytes to the neighboring keratinocytes are induced by ultraviolet radiation and modulated by autocrine and paracrine factors. Keratinocyte growth factor (KGF/fibroblast growth factor (FGF)7) is a paracrine mediator of human keratinocyte growth and differentiation. We evaluated the influence of KGF on
CARDINALI G, CECCARELLI, SIMONA, KOVACS D, ASPITE N, LOTTI, Lavinia Vittoria, TORRISI, Maria Rosaria, PICARDO M.   +6 more
openaire   +3 more sources