Results 111 to 120 of about 83,587 (297)
An improved phylogeny and revised taxonomy of Catillariaceae (Lecanoromycetes, Ascomycota)
TAXON, EarlyView.Abstract The boundaries of the family Catillariaceae have largely remained untested through phylogenetic methods. Recent studies have led to the transfer of several genera previously classified in Catillariaceae to the newly described family Leprocaulaceae. Despite these changes, the distinction between Catillariaceae, Leprocaulaceae, and Catinariaceae
Måns Svensson +2 more
wiley +1 more source
Effect of 2-H and 18-O water isotopes in kinesin-1 gliding assay [PDF]
, 2012 We show here the effects of heavy-hydrogen water (^2^H~2~O) and heavy-oxygen water (H~2~^18^O) on the gliding speed of microtubules on kinesin-1 coated surfaces.
Andy Maloney +2 more
core +1 more source
Molecular Mechanisms for Microtubule Length Regulation by Kinesin-8 and XMAP215 Proteins
, 2014 The cytoskeleton is regulated by a plethora of enzymes that influence the stability and dynamics of cytoskeletal filaments. Molecular motors of the kinesin-8 protein family depolymerise microtubules in a length-dependent manner, and experimental and ...
Frey, Erwin +2 more
core +1 more source
IFT cargo and motors associate sequentially with IFT trains to enter cilia of C. elegans
Nature CommunicationsIntraflagellar transport (IFT) orchestrates entry of proteins into primary cilia. At the ciliary base, assembled IFT trains, driven by kinesin-2 motors, can transport cargo proteins into the cilium, across the crowded transition zone. How trains assemble
Aniruddha Mitra +2 more
doaj +1 more source
Bio-ProtocolThe motile parameters of kinesin superfamily proteins are fundamental to intracellular transport. Single-molecule motility assays using total internal reflection fluorescence (TIRF) microscopy are a gold standard technique for measuring the motile ...
Tomoki Kita, Shinsuke Niwa
doaj +1 more source
Cryo-EM reveals the structural basis of microtubule depolymerization by kinesin-13s
Nature Communications, 2018 Kinesin-13s are microtubule depolymerases that lack motile activity. Here the authors present the cryo-EM structures of kinesin-13 microtubule complexes in different nucleotide bound states, which reveal how ATP hydrolysis is linked to conformational ...
Matthieu P.M.H. Benoit +2 more
doaj +1 more source
Effects of Tributyltin Chloride on Human Neuronal Differentiation and Mice Brain Development
Environmental Toxicology, EarlyView.ABSTRACT According to the developmental origins of health and disease hypothesis, perinatal exposure to an environmental toxicant during the development of the nervous system could cause a permanent cellular modification that may promote the appearance of neurodegenerative diseases at an older age.
Ester López‐Gallardo +10 more
wiley +1 more source
Neural Regeneration ResearchMicrotubules play a central role in cytoskeletal changes during neuronal development and maintenance. Microtubule dynamics is essential to polarity and shape transitions underlying neural cell division, differentiation, motility, and maturation.
Nuria Ruiz-Reig +2 more
doaj +1 more source
Disruption of Four Kinesin Genes in
BMC Cell Biology, 2008 Background Kinesin and dynein are the two families of microtubule-based motors that drive much of the intracellular movements in eukaryotic cells. Using a gene knockout strategy, we address here the individual function(s) of four of the 13 kinesin ...
Soga Ikko +3 more
doaj +1 more source
MAP1B Variants Disrupt Neuronal Migration: Insights From Three Novel Families
Clinical Genetics, EarlyView.Pathogenic variants in MAP1B have recently emerged as a cause of neurodevelopmental disorders characterized by intellectual disability, epilepsy, and cortical malformations, including periventricular nodular heterotopia (PVNH) and polymicrogyria (PMG).
Jessica Archer +4 more
wiley +1 more source