Results 121 to 130 of about 23,162 (298)
An improved phylogeny and revised taxonomy of Catillariaceae (Lecanoromycetes, Ascomycota)
TAXON, EarlyView.Abstract The boundaries of the family Catillariaceae have largely remained untested through phylogenetic methods. Recent studies have led to the transfer of several genera previously classified in Catillariaceae to the newly described family Leprocaulaceae. Despite these changes, the distinction between Catillariaceae, Leprocaulaceae, and Catinariaceae
Måns Svensson +2 more
wiley +1 more source
Intra-cellular transport of single-headed molecular motors KIF1A
, 2005 Motivated by experiments on single-headed kinesin KIF1A, we develop a model of intra-cellular transport by interacting molecular motors. It captures explicitly not only the effects of ATP hydrolysis, but also the ratchet mechanism which drives individual
Andreas Schadschneider +6 more
core +1 more source
Effects of Tributyltin Chloride on Human Neuronal Differentiation and Mice Brain Development
Environmental Toxicology, EarlyView.ABSTRACT According to the developmental origins of health and disease hypothesis, perinatal exposure to an environmental toxicant during the development of the nervous system could cause a permanent cellular modification that may promote the appearance of neurodegenerative diseases at an older age.
Ester López‐Gallardo +10 more
wiley +1 more source
In vitro Microtubule Bundling Assay under Physiological Conditions
Bio-Protocol, 2017 Kinesins play a role in organizing the mitotic spindle through the crosslinking of microtubules (MTs), made possible through binding sites at opposite ends of the holoenzyme.
Zach Geisterfer, Gin Tezuka, Li Tao
doaj +1 more source
MAP1B Variants Disrupt Neuronal Migration: Insights From Three Novel Families
Clinical Genetics, EarlyView.Pathogenic variants in MAP1B have recently emerged as a cause of neurodevelopmental disorders characterized by intellectual disability, epilepsy, and cortical malformations, including periventricular nodular heterotopia (PVNH) and polymicrogyria (PMG).
Jessica Archer +4 more
wiley +1 more source
Crystal structure of Zen4 in the apo state reveals a missing conformation of kinesin
Nature Communications, 2017 Kinesins are molecular motors that travel along microtubules through a nucleotide-dependent stepping mechanism. Here the authors present the crystal structure of Zen4 (kinesin-6) in an apo state that sheds light on a key stepping intermediate of kinesin.
Ruifang Guan +8 more
doaj +1 more source
Kinesin and dynein use distinct mechanisms to bypass obstacles
eLife, 2019 Kinesin-1 and cytoplasmic dynein are microtubule (MT) motors that transport intracellular cargoes. It remains unclear how these motors move along MTs densely coated with obstacles of various sizes in the cytoplasm.
Luke S Ferro +4 more
doaj +1 more source
Tau Differentially Regulates Kinesin-1, Kinesin-2, and Kinesin-3 [PDF]
Biophysical Journal, 2019 Dominique V. Lessard +1 more
openaire +1 more source
Cell Proliferation, EarlyView.FAM20A variants cause AI1G, marked by enamel defects, gingival overgrowth and ectopic calcifications. RNA sequencing of patient‐derived gingival fibroblasts showed dysregulated genes in adhesion, proliferation and signalling pathways. Functional assays revealed increased cell proliferation, impaired ECM interactions and osteogenesis, suggesting FAM20A ...
Kanokwan Sriwattanapong +9 more
wiley +1 more source