Results 111 to 120 of about 9,389 (207)

Size of chloroplasts in Arabidopsis mesophyll cells affects jasmonate biosynthesis

open access: yesPlant Biology, Volume 28, Issue 5, Page 1330-1342, August 2026.
The relationship between chloroplast structure and hormone biosynthesis capacity is poorly understood. This study shows that mutants harbouring giant chloroplasts produce more jasmonic acid upon mechanical stress than wild‐type plants, suggesting that organellar architecture is a previously unrecognized factor associated with plant hormone biosynthesis
R. Baral   +6 more
wiley   +1 more source

Chromosomal Instability Drives Glioblastoma Heterogeneity and Therapeutic Opportunities

open access: yesAdvanced Science, Volume 13, Issue 39, 13 July 2026.
ABSTRACT Glioblastoma, the most aggressive and lethal form of brain cancer, is defined by profound genomic instability, with Chromosomal Instability (CIN) playing a central role in driving tumor progression, therapy resistance, and poor prognosis. CIN is characterized by numerical and structural alterations, is driven by mechanisms such as mitotic ...
Amarnath Pal   +3 more
wiley   +1 more source

Spatiotemporal Control of Formation of Dynamic Protein Fiber Assemblies via Photophysical Effects of a Focused Laser Beam

open access: yesAdvanced Science, Volume 13, Issue 40, 17 July 2026.
Tightly focused laser irradiation can accumulate tubulin proteins at/around the laser focus, which leads to the formation of highly ordered microtubule assemblies. The assemblies can exhibit various dynamic behaviors such as radial motion, bundling, and flagella‐like rotation with motor protein and chemical energy, highlighting as a unique tool for ...
Hiroshi Y. Yoshikawa   +16 more
wiley   +1 more source

Post‐LECA Origin and Diversification of an Axonemal Outer Arm Dynein Motor

open access: yesCytoskeleton, Volume 83, Issue 7, Page 457-465, July 2026.
ABSTRACT Dyneins were present in the last eukaryotic common ancestor (LECA) and play key roles in eukaryotic biology. Axonemal dyneins form the inner and outer arms that power ciliary beating, and it has long been recognized that outer arms in some organisms contain two different heavy chain motors, whereas those from other species contain a third unit
Stephen M. King
wiley   +1 more source

A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside

open access: yesInterdisciplinary Medicine, Volume 4, Issue 4, July 2026.
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione   +2 more
wiley   +1 more source

Membrane‐type I metalloproteinase (MT1‐MMP): A key modifier of extracellular matrix microenvironment

open access: yesThe FEBS Journal, Volume 293, Issue 13, Page 4085-4097, July 2026.
MT1‐MMP: A cellular microenvironment modifier. MT1‐MMP is a major cellular microenvironment modifier, maintaining collagen homeostasis by degrading excess collagen (A), creating a migration path in motile cells such as cancer cells (B), modulating local microenvironmental signaling by cleaving transmembrane receptors (C), and destroying tissue ...
Yoshifumi Itoh, Masaki Inada
wiley   +1 more source

Identification of Distinct Interacting Proteins of Giardia lamblia Centrins Using Yeast Two‐Hybrid Assays

open access: yesJournal of Eukaryotic Microbiology, Volume 73, Issue 4, July/August 2026.
ABSTRACT Giardia lamblia, a protozoan parasite that causes diarrhea in humans, contains two centrins implicated in cellular morphology and cell division. To identify proteins interacting with each G. lamblia centrin (GlCent), we performed a yeast two‐hybrid assay.
Mee Young Shin   +2 more
wiley   +1 more source

From Synapses to Circuits, the Role of KIBRA and the WWC Family in Adaptive Brain Function

open access: yesJournal of Neurochemistry, Volume 170, Issue 7, July 2026.
KIBRA (WWC1) has been the subject of scientific interest since its initial association with nonpathological variation in human memory performance. This review discusses subsequent work in animal models demonstrating that KIBRA supports memory function.
Lenora J. Volk
wiley   +1 more source

Motor Protein Disruption Critically Alters Organelle Trafficking and Excitation-Contraction Coupling. [PDF]

open access: yeseNeuro
Bansal H   +5 more
europepmc   +1 more source

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