Results 151 to 160 of about 29,043 (290)
KIF2beta , a new kinesin superfamily protein in non-neuronal cells, is associated with lysosomes and may be implicated in their centrifugal translocation [PDF]
, 1998 Niovi Santama
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Rethinking “Prebiotic Chemistry”
Perspectives of Earth and Space Scientists, Volume 6, Issue 1, December 2025.Abstract In origins‐of‐life research, the term “prebiotic chemistry” is commonly used to describe processes thought to be related to or required for the emergence of life. However, it suffers from several potential drawbacks that have caused the present group of authors to rethink their usage of the term.
Michael L. Wong +2 more
wiley +1 more source
Oxidative denaturation of Cu/Zn‐superoxide dismutase associated with neurodegenerative diseases
Protein Science, Volume 34, Issue 11, November 2025.Abstract Misfolding of mutant Cu/Zn‐superoxide dismutase (SOD1) is a well‐established pathological feature of familial amyotrophic lateral sclerosis (ALS). While amino acid substitutions in mutant SOD1 destabilize its structure and promote misfolding, oxidation has also been implicated in the pathological alterations of wild‐type SOD1, particularly in ...
Moeno Yoshida +9 more
wiley +1 more source
Kinesin undergoes a 9 S to 6 S conformational transition.
, 1992 David D. Hackney +2 more
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ChemMedChem, Volume 20, Issue 19, October 6, 2025.It is reported for the first time that atropisomeric (R)‐[1,1′‐binaphthalene]‐2,2′‐diamine (R‐BINAM, 1(R)), but not (S)‐[1,1′‐binaphthalene]‐2,2′‐diamine (S‐BINAM, 1(S)), is a moderately potent spindle poison, causing antiproliferation, depolymerization of microtubules, multipolar spindles, pericentriolar material (PCM) fragmentation, mitotic ...
Malte Eichelbaum, Patrick J. Bednarski
wiley +1 more source
Kinesins and Myosins: Molecular Motors that Coordinate Cellular Functions in Plants.
Annual Review of Plant Biology, 2018 A. Nebenführ, R. Dixit
semanticscholar +1 more source
Molecular Oncology, Volume 19, Issue 10, Page 2951-2966, October 2025.Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho +11 more
wiley +1 more source
Microtubule movement by a biotinated kinesin bound to streptavidin-coated surface.
, 1994 Elise Berliner +5 more
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Intersection Between Local Anesthetics and Cancer Biology: What Now? Where Are We Going?
Advanced Biology, Volume 9, Issue 10, October 2025.Local anesthetics (LAs), widely used in anesthesia, may also play a role in cancer treatment by inhibiting tumor growth, reducing metastasis, and enhancing immune responses. They modulate key pathways like AKT/mTOR and RAS/ERK while affecting angiogenesis and tumor innervation and the immune response.
Eduardo Nunez‐Rodriguez +3 more
wiley +1 more source