Results 151 to 160 of about 23,162 (298)

RNA‐Binding Proteins and Ferroptosis in Cancer: Mechanism and Therapeutic Implications

open access: yesMedComm – Oncology, Volume 5, Issue 1, March 2026.
Ferroptosis critically influences cancer cell fate and represents a promising therapeutic strategy. Emerging evidence identifies RNA‐binding proteins (RBPs) as key post‐transcriptional regulators of ferroptosis. The figure summarizes ferroptosis‐related RBPs across cancers: blue RBPs act as tumor suppressors by promoting ferroptosis, whereas red RBPs ...
Linlin Chang   +6 more
wiley   +1 more source

Unraveling Lysosomal Exocytosis: From Molecular Mechanisms to Physiological Functions

open access: yesTraffic, Volume 27, Issue 1, March 2026.
Lysosomal exocytosis is propelled by specific molecular mechanisms that direct its microtubule‐dependent transport and subsequent fusion with the plasma membrane. This process fulfills essential physiological functions such as plasma membrane repair, maintenance of cellular homeostasis, and participation in signal transduction.
Shanshan Jiang   +7 more
wiley   +1 more source

Extracellular Vesicles: Biology, Intercellular Communication and Therapeutic Potential in Diabetes

open access: yesAdvanced Therapeutics, Volume 9, Issue 2, February 2026.
Exosome packaging in diabetes mellitus is depicted. Induced expression levels of RBP4, WNT related proteins, TGFB1, BMPs, VEGFs, STAT3, Calpain2 and altered expression levels of microRNAs in the exosomes are responsible for the inflammatory actions, defective central metabolism, myofibroblasts proliferation, dysregulated cell migration, cell ...
Swayam Prakash Srivastava   +9 more
wiley   +1 more source

A “slow” homotetrameric kinesin-related motor protein purified from Drosophila embryos.

open access: hybrid, 1994
Douglas G. Cole   +3 more
openalex   +1 more source

Unique Function of Kinesin Kif5A in Localization of Mitochondria in Axons [PDF]

open access: bronze, 2014
Philip D. Campbell   +5 more
openalex   +1 more source

Unconventional Secretion of Angiogenic Sonic Hedgehog–Containing Extra‐Large Extracellular Vesicles is Driven by PI3K–Rab18‐GDP Signalling

open access: yesJournal of Extracellular Biology, Volume 5, Issue 2, February 2026.
Human mesenchymal stem cells conditionally secrete sonic hedgehog (SHH)‐containing extra‐large extracellular vesicles (XLEVs) upon PI3K activation, which enriches the GDP‐bound form of Rab18. Rab18‐GDP drives perinuclear maturation and polarized vertical release of SHH‐XLEVs via Hsp90α‐ and nSMase2‐dependent mechanisms.
Shuo Wang   +3 more
wiley   +1 more source

Stimuli‐Responsive Chemical Systems That Mimic Biological Dynamics

open access: yesChemistry – A European Journal, Volume 32, Issue 1, 2 January 2026.
Chemists are designing synthetic systems that mimic life's dynamic behaviors, such as motion, sensing, adaptation, and compartmentalization, by integrating reaction networks with stimuli like light, pH, and chemical fuels. This mini‐review surveys molecular machines, responsive materials, nucleic acid networks, and artificial cells, highlighting how ...
Antonio Aguanell   +3 more
wiley   +1 more source

Carbon Quantum Dots Assisted Virus Tracking: From Skin to Brain

open access: yesAdvanced Materials, Volume 38, Issue 6, 27 January 2026.
A novel carbon quantum dots‐dissolvable microneedle, CQDs‐dMN system, enables painless delivery and real‐time tracking of HSV‐1. The HSV‐1 is labeled with fluorescent CQDs and delivered to the skin dermis, minimizing damage compared to traditional methods.
Yaxiu Feng   +11 more
wiley   +1 more source

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