Results 11 to 20 of about 29,043 (290)
The functions of kinesin and kinesin-related proteins in eukaryotes [PDF]
Cell Adhesion & Migration, 2020 Kinesins constitute a superfamily of ATP-driven microtubule motor enzymes that convert the chemical energy of ATP hydrolysis into mechanical work along microtubule tracks. Kinesins are found in all eukaryotic organisms and are essential to all eukaryotic
Iftikhar Ali, Wei-Cai Yang
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The mechanism of kinesin inhibition by kinesin-binding protein [PDF]
eLife, 2020 Subcellular compartmentalisation is necessary for eukaryotic cell function. Spatial and temporal regulation of kinesin activity is essential for building these local environments via control of intracellular cargo distribution.
Joseph Atherton +8 more
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Potential roles for Kinesins at the cortical division site
Frontiers in Plant Science, 2012 Spatial control of cytokinesis is critical for cell and plant morphology. The plane of cell division is established at G2/M transition and is initially demarcated at the cortex of the cell by the cytoskeletal preprophase band (PPB) and subsequently ...
Elisabeth eLipka, Sabine eMüller
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HPV16 entry requires dynein for minus-end transport and utilizes kinesin Kif11 for plus-end transport along microtubules during mitosis [PDF]
Journal of VirologyHuman papillomaviruses (HPVs) travel from the trans-Golgi network (TGN) to the condensed (mitotic) chromosomes during mitosis. Partially uncoated HPV capsids utilize a unique vesicular structure for trafficking and nuclear import, which is directed by ...
Timothy R. Keiffer +7 more
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Dissection of kinesin's processivity. [PDF]
PLoS ONE, 2009 The protein family of kinesins contains processive motor proteins that move stepwise along microtubules. This mechanism requires the precise coupling of the catalytic steps in the two heads, and their precise mechanical coordination.
Sarah Adio +4 more
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Molecular Motors in Blood–Brain Barrier Maintenance by Astrocytes [PDF]
Brain SciencesThe blood–brain barrier (BBB) comprises distinct cell types, including endothelial cells, pericytes, and astrocytes, and is essential for central nervous system (CNS) homeostasis by selectively regulating molecular transport and maintaining integrity. In
Ana Filipa Sobral +4 more
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eLife, 2014 Kinesins are a superfamily of microtubule-based ATP-powered motors, important for multiple, essential cellular functions. How microtubule binding stimulates their ATPase and controls force generation is not understood.
Joseph Atherton +6 more
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Kinesins in spermatogenesis† [PDF]
Biology of Reproduction, 2017 Kinesins are essential for the proper function of many types of polar cells, including epithelial cells, neurons, and sperm. Spermatogenesis is closely associated with many different kinesins. These kinesins participate in several fundamental processes, including mitotic and meiotic division, essential organelle transport, and the biogenesis of ...
D. Ma, Da-hui Wang, Wan-Xi Yang
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Nature, 1996 Chromosome segregation during mitosis depends on the action of the mitotic spindle, a self-organizing, bipolar protein machine which uses microtubules (MTs) and their associated motors. Members of the BimC subfamily of kinesin-related MT-motor proteins are believed to be essential for the formation and functioning of a normal bipolar spindle.
A. S. Kashlna +5 more
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bioRxiv, 2022 RNA transport and local translation provide spatial control of gene expression, and RNA binding proteins (RBPs) act as critical adapters in this multi-step process. Muscleblind-like (MBNL) RNA binding proteins, implicated in myotonic dystrophy and cancer,
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