Results 21 to 30 of about 23,162 (298)
Cell Reports, 2020 Summary: BORC is a multisubunit complex previously shown to promote coupling of mammalian lysosomes and C. elegans synaptic vesicle (SV) precursors (SVPs) to kinesins for anterograde transport of these organelles along microtubule tracks. We attempted to
Raffaella De Pace +7 more
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Universal and unique features of kinesin motors: Insights from a comparison of fungal and animal conventional kinesins [PDF]
, 1999 Kinesins are microtubule motors that use the energy derived from the hydrolysis of ATP to move unidirectionally along microtubules, The founding member of this still growing superfamily is conventional kinesin, a dimeric motor that moves processively ...
Hackney D.D. +5 more
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Microtubule-regulating kinesins [PDF]
Current Biology, 2013 Kinesins can regulate microtubule dynamics? The conventional function of kinesins, much like a molecular freight train, is to transport cargo by motoring along a microtubule (MT) track. But there exists another class of kinesins whose job relates more to track maintenance than transportation.
Sturgill, Emma G., Ohi, Ryoma
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The cooperative roles of two kinetoplastid-specific kinesins in cytokinesis and in maintaining cell morphology in bloodstream trypanosomes. [PDF]
PLoS ONE, 2013 The cytoskeleton of Trypanosoma brucei, a unicellular eukaryote and a parasitic protozoan, is defined by the subpellicular microtubule corset that is arranged underneath the plasma membrane. We recently identified two orphan kinesins, TbKIN-C and TbKIN-D,
Ying Wei +3 more
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Kinesin's backsteps under mechanical load [PDF]
, 2009 Kinesins move processively toward the plus end of microtubules by hydrolyzing ATP for each step. From an enzymatic perspective, the mechanism of mechanical motion coupled to the nucleotide chemistry is often well explained using a single-loop cyclic ...
Alberty +71 more
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Highly loaded behavior of kinesins increases the robustness of transport under high resisting loads.
PLoS Computational Biology, 2015 Kinesins are nano-sized biological motors which walk by repeating a mechanochemical cycle. A single kinesin molecule is able to transport its cargo about 1 μm in the absence of external loads.
Woochul Nam, Bogdan I Epureanu
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Frontiers in Genetics, 2021 Aspergillus niger is an important filamentous fungus in industrial biotechnology for the production of citric acid and enzymes. In the late 1980s, the A. niger N400/NRRL3 strain was selected for both fundamental and applied studies in relation to several
Ebru Demirci +8 more
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Bidirectional motion of filaments: Role of motor proteins and passive cross linkers [PDF]
, 2017 In eukaryotic cells, motor proteins (MP) bind to cytoskeletal filaments and move along them in a directed manner generating active stresses. During cell division a spindle structure of overlapping antiparallel microtubules (MT) form whose stability and ...
Chaudhuri, Debasish +4 more
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The functions of kinesin and kinesin-related proteins in eukaryotes
Cell Adhesion & Migration, 2020 Kinesins constitute a superfamily of ATP-driven microtubule motor enzymes that convert the chemical energy of ATP hydrolysis into mechanical work along microtubule tracks. Kinesins are found in all eukaryotic organisms and are essential to all eukaryotic
Iftikhar Ali, Wei-Cai Yang
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Comprehensive structural model of the mechanochemical cycle of a mitotic motor highlights molecular adaptations in the kinesin family [PDF]
, 2014 Kinesins are responsible for a wide variety of microtubule-based, ATP-dependent functions. Their motor domain drives these activities but the molecular adaptations that specify these diverse and essential cellular activities are poorly understood.
Goulet, Adeline +5 more
core +3 more sources