Results 71 to 80 of about 23,162 (298)
An open source LABVIEW platform for simulating image series of fluorescent microtubules in gliding assays [PDF]
, 2010 We describe an open-source LabVIEW software platform for generating simulated images of microtubules in gliding motility assays.
Lawrence J. Herskowitz, Steven J. Koch
core +2 more sources
Oncogenic role of kinesin proteins and targeting kinesin therapy
Cancer Science, 2013 The kinesin superfamily (KIF) is a group of proteins that share a highly conserved motor domain. Except for some members, many KIF proteins have adenosine triphosphatase activity and microtubule‐dependent plus‐end motion ability. Kinesins participate in several essential cellular functions, including mitosis, meiosis and the transport of macromolecules.
Xinran, Liu, Hao, Gong, Kun, Huang
openaire +3 more sources
Advanced Science, EarlyView.High light exposure triggers an epidermis‐specific remodeling of mitochondria and ER in Arabidopsis, driven by chloroplast‐derived signals. Live‐cell imaging shows that HL rapidly suppresses mitochondrial motility, followed by fusion‐driven elongation and ER cisternal expansion.
Evan R. Angelos +12 more
wiley +1 more source
Cooperative transport by small teams of molecular motors [PDF]
, 2006 Molecular motors power directed transport of cargoes within cells. Even if a single motor is sufficient to transport a cargo, motors often cooperate in small teams.
Klumpp, Stefan +2 more
core +2 more sources
Mitotic Kinesins: A Reason to Delve into Kinesin-12 [PDF]
Current Biology, 2014 The failure of kinesin-targeting cancer drugs is thought to result from functional redundancy of mitotic kinesins. A new study provides mechanistic insights into kinesin-12 that help to explain its targeting to kinetochore fibers and its ability to compensate for inhibition of kinesin-5.
openaire +2 more sources
NuSAP Safeguards Centriole Integrity to Mediate CEP57‐CEP152 Torus Recruitment for Proper Engagement
Advanced Science, EarlyView.This study reveals a novel role for the microtubule stabilizer NuSAP at centrioles. NuSAP depletion destabilizes the centriole's tubulin structure, causing premature disengagement, PCM defects, and mis‐localization of the CEP57‐CEP63‐CEP152 complex. By reinforcing centriole architecture, NuSAP enables early CEP57 loading and initiates a newly proposed ...
Shiyu Zhang +8 more
wiley +1 more source
Phylogenetic analysis of the kinesin superfamily from Physcomitrella
Frontiers in Plant Science, 2012 Kinesins are an ancient superfamily of microtubule dependent motors. They participate in an ex-tensive and diverse list of essential cellular functions, including mitosis, cytokinesis, cell polari-zation, cell elongation, flagellar development, and ...
Zhiyuan eShen +4 more
doaj +1 more source
A Statistical Mechanics Model to Decode Tissue Crosstalk During Graft Formation
Advanced Science, EarlyView.We introduce a statistical mechanics framework to decode the genomic crosstalk governing plant grafting. By integrating evolutionary game theory with transcriptomics, we reconstruct idopNetworks (informative, dynamic, omnidirectional, and personalized networks) that map scion–rootstock interactions.
Ang Dong +4 more
wiley +1 more source
Interaction Between Motor Domains Can Explain the Complex Dynamics of Heterodimeric Kinesins
, 2007 Motor proteins are active enzyme molecules that play a crucial role in many biological processes. They transform the chemical energy into the mechanical work and move unidirectionally along rigid cytoskeleton filaments.
A. Yildiz +6 more
core +2 more sources
Surface topography of microtubule walls decorated with monomeric and dimeric kinesin constructs [PDF]
, 2000 The surface topography of opened-up microtubule walls (sheets) decorated with monomeric and dimeric kinesin motor domains was investigated by freeze-drying and unidirectional metal shadowing.
Doerhoefer, Monika +6 more
core +2 more sources