Results 81 to 90 of about 15,656 (252)

Kinesin's backsteps under mechanical load [PDF]

, 2009
Kinesins move processively toward the plus end of microtubules by hydrolyzing ATP for each step. From an enzymatic perspective, the mechanism of mechanical motion coupled to the nucleotide chemistry is often well explained using a single-loop cyclic ...
Alberty, Alonso, Asbury, Baker, Beeg, Bell, Block, Block, Block, Brady, Brant, Carter, Changbong Hyeon, Chemla, Coppin, Coppin, Cross, Cross, Fisher, Fisher, Gelles, Gilbert, Gross, Guydosh, Hackney, Hackney, Howard, Hunt, Hyeon, Hyeon, Itoh, José N. Onuchic, Kawaguchi, Klumpp, Kojima, Kolomeisky, Liepelt, Liphardt, Lipowsky, Ma, Meyhofer, Mickler, Mori, Moyer, Muller, Nishiyama, Nishiyama, Oster, Qian, Qu, Reimann, Rice, Rice, Ross, Russell, Schief, Schief, Schnitzer, Schnitzer, Stefan Klumpp, Svoboda, Taniguchi, Thirumalai, Tsygankov, Uemura, Uemura, Vale, Vale, Visscher, Wu, Yildiz, Yildiz   +71 more
core   +1 more source

Interaction Between Actin and Microtubules During Plant Development

Cytoskeleton, EarlyView.
ABSTRACT The dynamic interaction between actin filaments (AFs) and microtubules (MTs) plays a crucial role in regulating key developmental and physiological processes in plant cells, particularly in the formation of specialized cell types with distinct shapes and functions, such as pollen tubes, trichomes, and leaf epidermal cells.
Zining Wu, Lidong Gao, M. Arif Ashraf, Qiong Nan   +3 more
wiley   +1 more source

Stochastic modeling of cargo transport by teams of molecular motors

, 2013
Many different types of cellular cargos are transported bidirectionally along microtubules by teams of molecular motors. The motion of this cargo-motors system has been experimentally characterized in vivo as processive with rather persistent ...
A. Kunwar, B. Trinczek, D.T. Gillespie, D.T. Gillespie, G. Steinberg, K. Döhner, M.A. Welte, M.A. Welte, M.J.I. Müller, N. Hirokawa, N. J. Carter, R. Mallik, S. Klein, S.P. Gross   +13 more
core   +1 more source

PEK14: A Kinesin‐4 Necessary for Male‐Derived Fertility in Arabidopsis thaliana

Cytoskeleton, EarlyView.
ABSTRACT Of the 61 kinesins annotated in Arabidopsis thaliana, many are still without assigned function. Here, we have screened an insertional mutant library of Arabidopsis pollen‐expressed kinesins for fertility defects. Insertional mutants for three kinesins showed a significant reduction in seed set.
Isabella N. Mendes, Norman R. Groves, Jessica Z. Li, Lily N. Thompson, Brian J. Smith, Aman Y. Husbands, Iris Meier   +6 more
wiley   +1 more source

Cytoskeleton: A catastrophic kinesin [PDF]

Current Biology, 1996
The 'plus' ends of microtubules exhibit dynamic instability, switching stochastically from growth to shortening phases. The first endogenous regulator of such 'catastrophes' has been identified, and is a kinesin-related microtubule motor protein.
Waters, Jennifer C, Salmon, E.D
openaire   +2 more sources

Nuclear Entanglement: New Insights Into the Role of Cytoskeleton and Nucleoskeleton in Plant Nuclear Function

Cytoskeleton, EarlyView.
ABSTRACT Of the three types of cytoskeleton known in animals—actin, microtubules, and intermediate filaments—only actin and microtubules exist in plants. Both play important roles in cellular shaping, organelle movement, organization of the endomembrane system, and cell signaling.
Norman R. Groves, Katelyn Amstutz, Lily A. Schumacher, Iris Meier   +3 more
wiley   +1 more source

A standardized kinesin nomenclature [PDF]

The Journal of Cell Biology, 2004
In recent years the kinesin superfamily has become so large that several different naming schemes have emerged, leading to confusion and miscommunication. Here, we set forth a standardized kinesin nomenclature based on 14 family designations. The scheme unifies all previous phylogenies and nomenclature proposals, while allowing individual sequence ...
Lawrence, Carolyn J, Dawe, R Kelly, Christie, Karen R, Cleveland, Don W, Dawson, Scott C, Endow, Sharyn A, Goldstein, Lawrence SB, Goodson, Holly V, Hirokawa, Nobutaka, Howard, Jonathon, Malmberg, Russell L, McIntosh, J Richard, Miki, Harukata, Mitchison, Timothy J, Okada, Yasushi, Reddy, Anireddy SN, Saxton, William M, Schliwa, Manfred, Scholey, Jonathan M, Vale, Ronald D, Walczak, Claire E, Wordeman, Linda   +21 more
openaire   +4 more sources

Making Two out of One: Kinesin Motors Driving Plant Cell Division

Cytoskeleton, EarlyView.
ABSTRACT The Kinesin superfamily of microtubule dependent motors is present in all eukaryotes. Not all of the subfamilies are represented in all kingdoms, and the ones that are do not always show conserved functions. Tight control of the cytoskeleton is essential for proper progression and completion of mitosis and cytokinesis, and key functions are ...
Choy Kriechbaum, Sabine Müller
wiley   +1 more source

Dynein catch bond as a mediator of codependent bidirectional cellular transport

, 2019
Intracellular bidirectional transport of cargo on microtubule filaments is achieved by the collective action of oppositely directed dynein and kinesin motors.
Chandel, Sameep, Chaudhuri, Abhishek, Gupta, Nisha, Mitra, Mithun K., Muhuri, Sudipto, Nair, Anil, Naskar, Supriyo, Puri, Palka   +7 more
core   +1 more source

Purification, Fluorescent Labeling, and Detyrosination of Mammalian Cell Tubulin for Biochemical Assays

Cytoskeleton, EarlyView.
ABSTRACT Microtubules play essential roles in numerous cellular processes. All microtubules are built from the protein tubulin, yet individual microtubules can differ spatially and temporally due to their tubulin isotype composition and post‐translational modifications (PTMs).
Ezekiel C. Thomas, Yang Yue, Morgan L. Pimm, Takashi Hotta, Ryoma Ohi, Kristen J. Verhey   +5 more
wiley   +1 more source