Results 171 to 180 of about 44,237 (280)
Cohesin-mediated stabilization of the CCAN complex at kinetochores in mitosis. [PDF]
Haase J+7 more
europepmc +1 more source
The proposed updated classification of humeroradial synostosis is based on the molecular pathways of the genes involved: (1) chondrogenesis and osteogenesis; (2) limb development and patterning; (3) genome regulation. Thus, pathologies belonging to the same molecular type may have overlapping clinical phenotypes, helping to structure the diagnostic ...
Fiona Leduc+5 more
wiley +1 more source
White–Sutton Syndrome: Insight of an Italian Cohort of 19 Subjects
New insights into White–Sutton syndrome with a collection of 19 Italian patients. Due to its complexity, we stress the importance of a systematic evaluation following the diagnosis and a thoughtful management of patients. Preliminary genotype–phenotype correlation analysis suggests the association between disruptive splicing variants and more severe ...
Anna Facchini+14 more
wiley +1 more source
Cell cycle dependent methylation of Dam1 contributes to kinetochore integrity and faithful chromosome segregation. [PDF]
Mishra PK+11 more
europepmc +1 more source
Active nucleoli have the capability to release perinuclear heterochromatin, which is a novel event of iPSC reprogramming. ABSTRACT Ribosome biogenesis occurs within the nucleolus, with the initial step being the transcription of ribosomal DNA (rDNA). Although rDNA transcription is limited in somatic cells, it is more active in stem cells. Nevertheless,
Yuchen Sun+7 more
wiley +1 more source
MPS1 promotes timely spindle bipolarization to prevent kinetochore-microtubule attachment errors in oocytes. [PDF]
Yoshida S+3 more
europepmc +1 more source
Mesenchymal stem cell‐mediated mitochondrial transfer regulates the fate of B lymphocytes
Mesenchymal stem cells (MSCs) modulate immune responses by transferring mitochondria to immune cells, including B lymphocytes. This study demonstrates that mitochondrial transfer to CD19+ cells is linked to reactive oxygen species levels, mitophagy and activation. Mitochondria acquisition enhances B cell viability and proliferation while downregulating
Veronika Somova+8 more
wiley +1 more source
Phosphorylation of CENP-C by PLK1 ensures accurate chromosome congression during mitosis. [PDF]
He S+11 more
europepmc +1 more source