Results 171 to 180 of about 105,405 (279)

Tetraopes Milkweed Beetle Genomes Elucidate the Adaptive Basis of a Temperate Coevolutionary Radiation

Molecular Ecology Resources, Volume 26, Issue 3, April 2026.
ABSTRACT The coevolutionary radiation of 27 species of Tetraopes longhorned beetles and their Asclepias milkweed hosts represents a classic example of adaptive evolution driven by plant chemical defences and herbivore counteradaptations. Investigations to date, however, have focused on a single species, Tetraopes tetrophthalmus, which feeds on the ...
Sangil Kim, Brian D. Farrell
wiley   +1 more source

M18BP1 valency and a distributed interaction footprint determine epigenetic centromere specification in humans. [PDF]

EMBO J
Walstein K, Hill L, Vogt D, Oberste-Lehn L, Janning P, Vetter IR, Pan D, Musacchio A.   +7 more
europepmc   +1 more source

Comparative Genomics Provide Insights Into Karyotype Evolution in Vespertilionid Bats (Vespertilionidae, Chiroptera)

Molecular Ecology Resources, Volume 26, Issue 3, April 2026.
ABSTRACT Studies elucidating the molecular basis and evolutionary consequences of karyotypic changes in mammals remain scarce. Here, we investigate chromosomal evolution by focusing on two contrasting lineages within the family Vespertilionidae (Chiroptera): the karyotypically variable tribe Pipistrellini and the highly conserved genus Myotis ...
Linjing Lan, Xin Zhang, Jinjin Xie, Xiaohui Lin, Xihong Hong, Wenhui Nie, Jinhuan Wang, Weiting Su, Fengtang Yang, Guimei He, Xiuguang Mao   +10 more
wiley   +1 more source

Identification and characterization of components of the Candida albicans inner kinetochore. [PDF]

Genetics
Xiong EH, Fu C, Lin ZY, Wong CJ, Nathwani K, Wang H, Gingras AC, Robbins N, Cowen LE.   +8 more
europepmc   +1 more source

Risdiplam Impact in Treatment Naïve and Non‐Naïve Pediatric and Adult Patients With Spinal Muscular Atrophy

European Journal of Neurology, Volume 33, Issue 4, April 2026.
This 36‐month prospective study of 34 symptomatic SMA patients (ages 6.9–50.9 years) found significant motor and quality of life improvements with risdiplam treatment. Treatment‐naïve patients showed notable gains in MFM‐32 and RULM scores, while those switching therapies improved in MFM‐32.
Pak On Patrick Yee, Hayley Hoi Ning Ip, Michael Kwan Leung Yu, Pui Kei Cheng, Wilfred Hing Sang Wong, Patrick Pak Hei Ng, Nathan Sheung Tat Kwong, Priscillia Lam, Mei Wun Cheung, Angel Tung, Stephen Chan, Shirley Ng, Wai Lan Yeung, Sheila Wong, Yuen Gao, Shirley Pang, Sophelia Hoi Shan Chan   +16 more
wiley   +1 more source

RB dependent transcriptional regulation at mitotic centromeres preserves genome stability. [PDF]

Life Sci Alliance
Crowley EA, Manning AL.
europepmc   +1 more source

Rearranging kinetochores [PDF]

Genome Biology, 2000
openaire   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, Volume 20, Issue 3, Page 727-752, March 2026.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Kinetochore mutations and histone phosphorylation pattern changes accompany holo- and macro-monocentromere evolution. [PDF]

Nat Commun
Kuo YT, Neumann P, Chen J, Fuchs J, Schubert V, Kumke K, Sader MA, Melzer M, Zhu Z, Himmelbach A, Hentrich H, Macas J, Houben A.   +12 more
europepmc   +1 more source

Transition From Juvenile Dermatomyositis to Spondyloarthritis: A Novel Overlapping Inflammatory Phenotype

ACR Open Rheumatology, Volume 8, Issue 3, March 2026.
Objective Juvenile dermatomyositis (JDM) is a rare childhood inflammatory myopathy, whereas spondyloarthritis (SpA) is an inflammatory arthropathy characterized by enthesitis and peripheral or axial involvement. We describe a series of patients diagnosed with JDM in childhood who later fulfilled classification criteria for SpA, a sequential phenotype ...
Austen Grooms, Ioannis Karageorgiou, Kerry Mychaliska, James Birmingham   +3 more
wiley   +1 more source