Results 31 to 40 of about 105,050 (263)
Tumor Biology, 2017 Spindle and kinetochore–associated protein 1 is a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation.
Kai Wang +5 more
doaj +1 more source
Spatiotemporal dynamics of Spc105 regulates the assembly of the Drosophila kinetochore [PDF]
Open Biology, 2012 The formation of kinetochores shortly before each cell division is a prerequisite for proper chromosome segregation. The synchronous mitoses of Drosophila syncytial embryos have provided an ideal in vivo system to follow kinetochore assembly kinetics and
Zsolt Venkei +7 more
doaj +1 more source
STAR Protocols, 2021 Summary: This protocol measures the 3D Euclidean distance (Δ3D) between two/three fluorescently labeled kinetochore components in fixed samples using Kinetochore Delta software (KiDv1.0.1, MATLAB based).
Tsvetelina E. Germanova +4 more
doaj +1 more source
Checkpoint proteins come under scrutiny [PDF]
, 2013 Details are emerging of the interactions between the kinetochore and various spindle checkpoint proteins that ensure that sister chromatids are equally divided between daughter cells during cell ...
Millar, Jonathan B. A. +1 more
core +1 more source
How to halve ploidy : lessons from budding yeast meiosis [PDF]
, 2012 Maintenance of ploidy in sexually reproducing organisms requires a specialized form of cell division called meiosis that generates genetically diverse haploid gametes from diploid germ cells.
Arumugam, Prakash +2 more
core +1 more source
The Drosophila histone variant H2A.V works in concert with HP1 to promote kinetochore-driven microtubule formation [PDF]
, 2015 Unlike other organisms that have evolved distinct H2A variants for different functions, Drosophila melanogaster has just one variant which is capable of filling many roles.
Cenci, Giovanni, Verni', Fiammetta
core +1 more source
eLife, 2023 At each cell division, nanometer-scale components self-organize to build a micron-scale spindle. In mammalian spindles, microtubule bundles called kinetochore-fibers attach to chromosomes and focus into spindle poles.
Manuela Richter +5 more
doaj +1 more source
Cell Division: Kinetochores SKAdaddle [PDF]
Current Biology, 2013 Accurate chromosome segregation during cell division requires that kinetochores couple microtubule dynamics to chromosome movement. New research reveals that the kinetochore-associated Ska1 complex hangs on to depolymerizing microtubules and brings some important friends along for the ride.
Ye, Anna A., Maresca, Thomas J.
openaire +2 more sources
Chromosome Oscillations in Mitosis [PDF]
, 2005 Successful cell division requires a tight regulation of chromosome motion via the activity of molecular motors. Many of the key players at the origin of the forces generating the movement have been identified, but their spatial and temporal organization ...
A. P. Joglekar +8 more
core +2 more sources
Studying Kinetochore Kinases [PDF]
, 2016 Mitotic kinetochores are signaling network hubs that regulate chromosome movements, attachment error-correction, and the spindle assembly checkpoint. Key switches in these networks are kinases and phosphatases that enable rapid responses to changing conditions.
Saurin, Adrian T., Kops, Geert J. P. L.
openaire +4 more sources