eLife, 2019 Lagging chromosome is a hallmark of aneuploidy arising from errors in the kinetochore–spindle attachment in animal cells. However, kinetochore components and cellular phenotypes associated with kinetochore dysfunction are much less explored in plants ...
Elena Kozgunova +2 more
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Ybp2 associates with the central kinetochore of Saccharomyces cerevisiae and mediates proper mitotic progression. [PDF]
PLoS ONE, 2008 The spindle checkpoint ensures the accurate segregation of chromosomes by monitoring the status of kinetochore attachment to microtubules. Simultaneous mutations in one of several kinetochore and cohesion genes and a spindle checkpoint gene cause a ...
Kentaro Ohkuni +4 more
doaj +1 more source
Compare and contrast the reaction coordinate diagrams for chemical reactions and cytoskeletal force generators. [PDF]
, 2013 Reaction coordinate diagrams are used to relate the free energy changes that occur during the progress of chemical processes to the rate and equilibrium constants of the process.
Scholey, Jonathan M
core +2 more sources
Exploring Plant Meiosis: Insights from the Kinetochore Perspective
Current Issues in Molecular Biology, 2023 The central player for chromosome segregation in both mitosis and meiosis is the macromolecular kinetochore structure, which is assembled by >100 structural and regulatory proteins on centromere DNA.
Kang-Di Zhou +8 more
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Chromosome segregation in plant meiosis [PDF]
, 2014 Faithful chromosome segregation in meiosis is essential for ploidy stability over sexual life cycles. In plants, defective chromosome segregation caused by gene mutations or other factors leads to the formation of unbalanced or unreduced gametes creating
De Storme, Nico +4 more
core +2 more sources
Molecular basis of outer kinetochore assembly on CENP-T
eLife, 2016 Stable kinetochore-microtubule attachment is essential for cell division. It requires recruitment of outer kinetochore microtubule binders by centromere proteins C and T (CENP-C and CENP-T).
Pim J Huis in 't Veld +8 more
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Identification of four unconventional kinetoplastid kinetochore proteins KKT22–25 in Trypanosoma brucei [PDF]
Open Biology, 2019 The kinetochore is a multi-protein complex that drives chromosome segregation in eukaryotes. It assembles onto centromere DNA and interacts with spindle microtubules during mitosis and meiosis. Although most eukaryotes have canonical kinetochore proteins,
Olga O. Nerusheva +2 more
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Kinetochore structure: electron spectroscopic imaging of the kinetochore. [PDF]
The Journal of cell biology, 1989 The structure of the kinetochore in thin section has been studied in the Indian muntjac by an electron spectroscopic imaging technique. This procedures allows the analysis of the distribution of phosphorus within the layers of the kinetochore. The results indicate that this element is a major component of both the inner and outer plates whereas it is ...
J B, Rattner, D P, Bazett-Jones
openaire +2 more sources
A comparison of the distribution of actin and tubulin in the mammalian mitotic spindle as seen by indirect immunofluorescence [PDF]
, 1977 Rabbit antibodies against actin and tubulin were used in an indirect immunofluorescence study of the structure of the mitotic spindle of PtK1 cells after lysis under conditions that preserve anaphase chromosome movement. During early prophase there is no
Cande, W. Zacheus +2 more
core +5 more sources
Plasmodium Condensin Core Subunits SMC2/SMC4 Mediate Atypical Mitosis and Are Essential for Parasite Proliferation and Transmission [PDF]
, 2020 Condensin is a multi-subunit protein complex regulating chromosome condensation and segregation during cell division. In Plasmodium spp., the causative agent of malaria, cell division is atypical and the role of condensin is unclear.
Abel, Steven +18 more
core +3 more sources