Results 31 to 40 of about 105,994 (204)

The Drosophila histone variant H2A.V works in concert with HP1 to promote kinetochore-driven microtubule formation [PDF]

, 2015
Unlike other organisms that have evolved distinct H2A variants for different functions, Drosophila melanogaster has just one variant which is capable of filling many roles.
Cenci, Giovanni, Verni', Fiammetta
core   +1 more source

Subcellular Euclidean distance measurements with multicolor fluorescence localization imaging in cultured cells

STAR Protocols, 2021
Summary: This protocol measures the 3D Euclidean distance (Δ3D) between two/three fluorescently labeled kinetochore components in fixed samples using Kinetochore Delta software (KiDv1.0.1, MATLAB based).
Tsvetelina E. Germanova, Emanuele Roscioli, Jonathan U. Harrison, Andrew D. McAinsh, Nigel J. Burroughs   +4 more
doaj   +1 more source

Prime movers : mechanochemistry of mitotic kinesins [PDF]

, 2014
Mitotic spindles are self-organizing protein machines that harness teams of multiple force generators to drive chromosome segregation. Kinesins are key members of these force-generating teams.
A Blangy, A Groen, A Hutterer, A Jannasch, A Karabay, A Toso, A Yildiz, AA Levesque, AB Asenjo, AC Groen, AE Butterfield, AF Huxley, AF Straight, AJ Roberts, AM Mulder, AM Saunders, Andrew McAinsh, AS Kashina, AS Khalil, B Gigant, B Owens, B Wickstead, BH Kwok, BH Kwok, BJ Grant, BT Schaar, C Antonio, C Hentrich, C Peters, C Thiede, C Wandke, CA Watts, CC Leduc, CE Walczak, CJ Lawrence, CK Hu, CL Parke, CL Rieder, CL Rieder, CM Whitehead, CTC Friel, CV Sindelar, CV Sindelar, D Vanneste, D Vanneste, DA Compton, E Doménech, E Karsenti, E Vladimirou, EG Sturgill, ER Hildebrandt, FJ Kull, FJ Kull, G Fink, GC Rogers, GJ Brouhard, GJ Gorbsky, GJPL Kops, H Aizawa, H Boleti, H Drechsler, H Funabiki, H Yardimci, HS Sardar, HS Sardar, HYK Kaan, I Brust-Mascher, I Brust-Mascher, I Minoura, IM Crevel, IM-TC Crevel, J Espeut, J Helenius, J Roostalu, J Roostalu, J Rosenblatt, J Stumpff, J Stumpff, J Stumpff, J Yajima, JC Cochran, JC Gatlin, JC Waters, JM Scholey, JPI Welburn, JR Aist, JR Cooper, JR McIntosh, JRJ Stout, JS Allingham, JS Weinger, K Hahlen, K Jaqaman, K Kaseda, K Kaseda, K Samejima, KE Gascoigne, KJ Verhey, KS Burbank, KW Wood, KW Wood, KY Lee, L Wordeman, LC Kapitein, LC Kapitein, LN Weaver, LR Sproul, M Braun, M Braun, M Glotzer, M Joshi, M Kikkawa, M Klejnot, M Mishima, M Nishiyama, M Wagenbach, MA Hoyt, MA Seeger, MC Alonso, ME Douglas, ME Tanenbaum, ME Tanenbaum, ME Tanenbaum, MI Mayr, MJ Korneev, ML Gupta, MT Valentine, MT Valentine, N Gudimchuk, N Hirokawa, N Hirokawa, N Joseph, NF Endres, NJ Carter, NJ Ganem, OO Rath, P Bieling, Q Chang, R Nitta, R Nunes Bastos, R Uehara, RB Case, RD Vale, Robert A. Cross, S Acar, S Cai, S Cane, S Debonis, S Diez, S Dumont, S Highsmith, S Inoué, S Oh, S Rice, S Rice, S Shastry, SF Bakhoum, SS Rosenfeld, SS Rosenfeld, SW Grill, T Krzysiak, T Maney, T Surrey, TJ Mitchison, TJ Mitchison, TM Kapoor, TT Ogawa, V Fridman, V Magidson, V Mountain, V Varga, VV Bormuth, W Saunders, WW Wang, X Su, X Su, Y Du, Y Kim, Y Kurasawa, Y Oguchi, Y Zhai, YF Dufrene, YM Lee, YY Okada, Z Yang   +184 more
core   +1 more source

Arabidopsis kinetochore fiber-associated MAP65-4 cross-links microtubules and promotes microtubule bundle elongation [PDF]

, 2010
The acentrosomal plant mitotic spindle is uniquely structured in that it lacks opposing centrosomes at its poles and is equipped with a connective preprophase band that regulates the spatial framework for spindle orientation and mobility.
Fache, Vincent, Gaillard, Jérémie, Van Damme, Daniël, Geelen, Danny, Neumann, Emmanuelle, Stoppin-Mellet, Virginie, Vantard, Marylin   +6 more
core   +3 more sources

Kinetochore-fiber lengths are maintained locally but coordinated globally by poles in the mammalian spindle

eLife, 2023
At each cell division, nanometer-scale components self-organize to build a micron-scale spindle. In mammalian spindles, microtubule bundles called kinetochore-fibers attach to chromosomes and focus into spindle poles.
Manuela Richter, Lila Neahring, Jinghui Tao, Renaldo Sutanto, Nathan H Cho, Sophie Dumont   +5 more
doaj   +1 more source

The Dam1 ring binds to the E-hook of tubulin and diffuses along the microtubule. [PDF]

, 2011
There has been much effort in recent years aimed at understanding the molecular mechanism by which the Dam1 kinetochore complex is able to couple microtubule depolymerization to poleward movement. Both a biased diffusion and a forced walk model have been
Barnes, Georjana, Drubin, David, Liu, Jian, Nakajima, Yuko, Nogales, Eva, Ramey, Vincent H, Wang, Hong-Wei, Wong, Amanda   +7 more
core   +2 more sources

Cell Division: Kinetochores SKAdaddle [PDF]

Current Biology, 2013
Accurate chromosome segregation during cell division requires that kinetochores couple microtubule dynamics to chromosome movement. New research reveals that the kinetochore-associated Ska1 complex hangs on to depolymerizing microtubules and brings some important friends along for the ride.
Ye, Anna A., Maresca, Thomas J.
openaire   +2 more sources

Structural plasticity of the living kinetochore [PDF]

, 2017
The kinetochore is a large, evolutionarily conserved protein structure that connects chromosomes with microtubules. During chromosome segregation, outer kinetochore components track depolymerizing ends of microtubules to facilitate the separation of ...
Akiyoshi, Al-Bassam, Aravamudhan, Aravamudhan, Asbury, Biggins, Biggins, Boris Rubinstein, Brian D. Slaughter, Chan, Cheeseman, Culotti, Daniel, De Wulf, Desai, Duffy, Field, Foley, Gandhi, Gao, Gardner, Gestaut, Grishchuk, Guimaraes, Hartwell, He, Hedges, Hill, Hornung, Hornung, Jaspersen, Jay R. Unruh, Jeffrey J. Lange, Jennifer L. Gerton, Jin, Jin, Joglekar, Joglekar, Joglekar, Joglekar, Karthik Dhatchinamoorthy, Kim, Kosco, Lampert, Liu, Longtine, Mallavarapu, Malvezzi, Manjunatha Shivaraju, Mayer, McAinsh, McIntosh, McKinney, Meng, Mieck, Miller, Miranda, Ng, Obuse, Pavelka, Pearson, Pfau, Podolski, Powers, Ramey, Sarangapani, Schleiffer, Schmidt, Severin, Shivaraju, Smith, Stephens, Su, Suzuki, Tanaka, Tien, Tytell, Umbreit, Usui, van Breugel, van Hooff, Visintin, Walczak, Wang, Welburn, Westermann, Westermann, Winey, Wisniewski, Wolyniak, Yuen   +90 more
core   +1 more source

Studying Kinetochore Kinases [PDF]

, 2016
Mitotic kinetochores are signaling network hubs that regulate chromosome movements, attachment error-correction, and the spindle assembly checkpoint. Key switches in these networks are kinases and phosphatases that enable rapid responses to changing conditions.
Saurin, Adrian T., Kops, Geert J. P. L.
openaire   +4 more sources

Balancing the kinetochore ledger [PDF]

Journal of Cell Biology, 2012
Reduction of polo-like kinase-1 (Plk1) at kinetochores as cells progress from prometaphase to metaphase is surprising given that the kinase is thought to stabilize kinetochore–microtubule (kt–MT) attachments. In this issue, Liu et al. (2012. J. Cell Biol.
Cane, Stuart, Maresca, Thomas J.
openaire   +2 more sources