Results 51 to 60 of about 6,100 (148)

Kinin B1 and B2 receptor deficiency protects against obesity induced by a high-fat diet and improves glucose tolerance in mice

Diabetes, Metabolic Syndrome and Obesity, 2015
Rafael L Morais,1 Elton D Silva,1 Vicência M Sales,1 Rafael Filippelli-Silva,1 Marcelo A Mori,1 Michael Bader,2 João B Pesquero1 1Department of Biophysics, Universidade Federal de São Paulo, São Paulo, Brazil; 2Max-Delbrü ...
Morais RL, Silva ED, Sales VM, Filippelli-Silva R, Mori MA, Bader M, Pesquero JB   +6 more
doaj  

Bradykinin Receptors in Metabolic Disorders: A Comprehensive Review

Drugs and Drug Candidates
The kallikrein–kinin system and its B1 and B2 receptors are key regulators in metabolic disorders such as obesity, diabetes, and insulin resistance. Obesity, a chronic and multifactorial condition often associated with comorbidities like type 2 diabetes ...
Jéssica Branquinho, Raquel Leão Neves, Michael Bader, João Bosco Pesquero   +3 more
doaj   +1 more source

Posterior Ciliary Artery Contraction by Bradykinin Receptor Subtypes and Implications for Retinal Blood Flow Dysfunction

Frontiers in Bioscience-Elite
Background: Low retinal blood flow and/or vasospasm represent major risk factors for the development of glaucomatous optic neuropathy (GON), a potentially blinding eye disease.
Najam A. Sharif, Sunny E Ohia, Madhura Kulkarni-Chitnis, Anthonia Okolie, Saima D. Chaudhry, Ya Fatou Njie-Mbye   +5 more
doaj   +1 more source

Mechanistic Insights into the Interaction Between Kinin Receptors and Histamine H2 Receptor Pathways in Oxidative Stress

Receptors
Reactive oxygen species (ROS) encompass various molecular oxygen derivatives naturally produced during aerobic metabolism, including superoxide anions, hydrogen peroxide, and hydroxyl radicals.
Marcos Fernandes Gregnani, Leonardo Martins, Wieslawa Agnieszka Fogel   +2 more
doaj   +1 more source

Reminiscences of Ervin G Erdös [PDF]

Scripta Medica, 2019
This article includes personal reminiscence of the great scientist Ervin G Erdös (1922-2019). Dr Erdös was born in Budapest, where he studied medicine. He finished his medical school in Munich, and obtained MD degree in 1952.
Igić Rajko
doaj  

Renin-angiotensin and kallikrein-kinin systems in diabetic retinopathy [PDF]

Scripta Medica, 2019
This brief review describes how two complex systems, the renin-angiotensin system (RAS) and the kallikrein-kinin system (KKS), affect the retina.
Igić Rajko
doaj  

Activation of Toll-like receptor 2 induces B₁ and B₂ kinin receptors in human gingival fibroblasts and in mouse gingiva. [PDF]

Sci Rep, 2019
Souza PPC, Lundberg P, Lundgren I, Magalhães FAC, Costa-Neto CM, Lerner UH.   +5 more
europepmc   +1 more source

Characterization of kinin receptors by bioassays.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica, 1995
1. Using the classical pharmacological criteria recommended by Schild, namely the order of potency of selective agonists (e.g., bradykinin, desArg9-bradykinin, [Hyp3]BK and [Aib7]BK) and the apparent affinity of competitive antagonists (e.g., DArg[Hyp3,DPhe7,Leu8]BK and WIN 64338), we have attempted to characterize B2 receptor subtypes.
F, Gobeil, D, Regoli
openaire   +1 more source

Antagonism of Kinin Receptors B1 and B2 Attenuates Folic Acid-Induced Tubulointerstitial Fibrosis in Mice. [PDF]

Basic Clin Pharmacol Toxicol
Estrela GR, Budu A, Silva J, Brito R, Wasinski F, Barrera-Chimal J, Araujo RC.   +6 more
europepmc   +1 more source

Expression of the genes encoding kinin receptors are increased in human carotid atherosclerotic plaques. [PDF]

Biomed Rep, 2015
Guo Y, Liu T, Li X, Zhang M, Shi L, Liu H.   +5 more
europepmc   +1 more source