Results 51 to 60 of about 6,579 (265)

Molecular Bases and Genetic Design of Rice Disease Resistance for Optimized Yield and Sustainable Agriculture

Advanced Science, EarlyView.
This study integrates rice immune perception, signal transduction, and resistance output into a multi‐omics framework. By combining high‐throughput sequencing, phenomics, and AI‐assisted design with marker‐assisted selection, gene editing, and rapid domestication, we aim to accelerate the precise breeding of disease‐resistant rice varieties by ...
Xinyue Hou, Yuanjiang Cui, Chaoqing Ding, Qian Qian, Deyong Ren   +4 more
wiley   +1 more source

Plant Metabolites Screening Identifies 7‐epi‐10‐Deacetyltaxol Inhibiting Cell Division by Interfering With the Cell Cycle and Microtubule Organization

Advanced Science, EarlyView.
In this study, an efficient screening system is developed for plant metabolites to find a compound, 7‐epi‐10‐deacetyltaxol, inhibits tissue elongation. It suppresses plant growth through brassinosteroid and microtubule pathways. It is later applied to animal cells and human tumor organoids, resulting in similar cell division suppression. These findings
Yan‐Jie Zhang, Yu‐Xuan Bai, Geng G. Tian, Bin Zhang, Ding‐Yi Lu, Qing‐Ping Yao, Wen‐Hao Tian, Xiao‐Na Wei, Jing‐Ting Yang, Ze‐Yu Xiong, Yi Lu, Yu‐Tong Jiang, Chun‐Hui Cai, Yu‐Ming Lu, Xian‐Qing Jia, Li‐Li Jing, Bao‐Jun Yang, Ying‐Xin Qi, Xin‐Xin Han, Ji Wu, Wen‐Hui Lin   +20 more
wiley   +1 more source

High atmospheric pressure rescues plant growth under humidity stress: A model for climate‐resilient deep underground agriculture

Deep Underground Science and Engineering, EarlyView.
High atmospheric pressure (120 kPa) in deep underground counteracts humidity‐induced physiological stress in plants, stabilizing water balance and enhancing antioxidative defenses. This synergy boosts biomass despite elevated humidity, demonstrating sustainable deep underground agriculture potential under climate uncertainty.
Yuxin He, Linglu Xu, Xiao Tan, Wenhua Zhuang, Naiwen Li, Chao Liu, Bo Tan   +6 more
wiley   +1 more source

Theranostic Potential of a New ⁶⁴Cu-Labeled NOTA-R954 Peptide Conjugate for Kinin B1R Expressing Prostate Cancer

Pharmaceutics
Background/Objectives: This study explores the potential of the inducible G protein-coupled kinin B1 receptor (B1R) as a target for the diagnosis and treatment of prostate cancer (PCa) and aims to develop the first theranostic agent targeting hB1R for ...
Sadaf Ghanaatgar Kasbi, Martin Savard, Frédéric Couture, Céléna Dubuc, Véronique Dumulon-Perreault, Marie-Edith Nepveu-Traversy, Samia Ait-Mohand, Robert Sabbagh, Sameh Geha, Brigitte Guérin, Yves Dory, Fernand Gobeil   +11 more
doaj   +1 more source

In Vitro Modeling of Bradykinin-Mediated Angioedema States

Pharmaceuticals, 2020
Kinins (peptides related to bradykinin, BK) are formed from circulating substrates, the kininogens, by the action of two proteases, the kallikreins.
François Marceau, Hélène Bachelard, Xavier Charest-Morin, Jacques Hébert, Georges E. Rivard   +4 more
doaj   +1 more source

Dysregulation of the kallikrein-kinin system in bronchoalveolar lavage fluid of patients with severe COVID-19

EBioMedicine, 2022
Summary: Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds to the angiotensin-converting enzyme 2 (ACE2) receptor, a critical component of the kallikrein-kinin system.
Caroline P. Martens, Pierre Van Mol, Joost Wauters, Els Wauters, Tanja Gangnus, Bernard Noppen, Hanne Callewaert, Jean H.M. Feyen, Laurens Liesenborghs, Elisabeth Heylen, Sander Jansen, Leydi Carolina Velásquez Pereira, Sirima Kraisin, Ipek Guler, Matthias M. Engelen, Anna Ockerman, Anke Van Herck, Robin Vos, Christophe Vandenbriele, Philippe Meersseman, Greet Hermans, Alexander Wilmer, Kimberly Martinod, Bjoern B. Burckhardt, Marc Vanhove, Marc Jacquemin, Peter Verhamme, Johan Neyts, Thomas Vanassche   +28 more
doaj   +1 more source

Genetic and Molecular Basis of Processing Traits and Genetic Improvement Progress in Major Fruit Crops

Future Postharvest and Food, EarlyView.
Processing quality in fruit crops is governed by complex genetic networks controlling texture, sweetness, color, browning, aroma, and nutritional quality. Advances in genomics, genomic selection, and genome editing enable the development of processing‐oriented cultivars with improved industrial performance, reduced postharvest losses, and enhanced ...
M. Ranjani, Kaviya Dharshini U, Shalini Gaur Rudra   +2 more
wiley   +1 more source

Intracellular proteolysis of kininogen by malaria parasites promotes release of active kinins

Malaria Journal, 2012
Background The malaria burden remains a major public health concern, especially in sub-Saharan Africa. The complex biology of Plasmodium, the apicomplexan parasite responsible for this disease, challenges efforts to develop new strategies to control the ...
Bagnaresi Piero, Barros Nilana MT, Assis Diego M, Melo Pollyana MS, Fonseca Raphael G, Juliano Maria A, Pesquero João B, Juliano Luiz, Rosenthal Philip J, Carmona Adriana K, Gazarini Marcos L   +10 more
doaj   +1 more source

Effect of bio‐fertilization and edapho‐climatic conditions on chickpea nodulation, grain yields, and seed protein in a Mediterranean context: a meta‐analysis approach

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Chickpeas (Cicer arietinum L.) serve as a protein‐rich staple, particularly in Mediterranean countries, where they are often grown in marginal and water‐stressed areas. This meta‐analysis synthesized evidence from peer‐reviewed publications across Mediterranean countries to assess how chickpea rhizobial inoculation influences chickpea ...
Amira Hachana, Amir Souissi, Lewis Ziska, Katherine Morgan, Carina Yiu, Issam Achour, Asma Bouatrous, Imen Hemissi, Hanen Arfaoui, Anissa Riahi, Manel Bouraoui, Bouaziz Sifi   +11 more
wiley   +1 more source

Pharmacological studies of kinins in venous smooth muscles

, 1981
The myotropic effects of bradykinin (BK) and other kinins in two isolated veins, the rabbit jugular and the guinea pig anterior mesenteric, have been studied.
J. Barabé, D. Regoli, P. Gaudreau, S. St-Pierre   +3 more
core   +1 more source