Results 21 to 30 of about 7,724 (208)

Comparative Analysis of Kisspeptin Levels and KISS1 Gene Polymorphism in Patients with Polycystic Ovary Syndrome (PCOS): Correlation with the Luteinizing Hormone-Follicle-Stimulating Hormone Ratio and PCOS-Associated Variables. [PDF]

Cureus
Talukdar C, Choudhary SS, Talukdar PM, Borah MS, Baishya AC.   +4 more
europepmc   +3 more sources

Kiss1 expressed in the amygdala in rodents [PDF]

Nature Reviews Endocrinology, 2011
Carol Wilson
openalex   +2 more sources

The molecular phenotype of kisspeptin neurons in the medial amygdala of female mice

Frontiers in Endocrinology, 2023
Reproduction is regulated through the hypothalamic-pituitary-gonadal (HPG) axis, largely via the action of kisspeptin neurons in the hypothalamus. Importantly, Kiss1 neurons have been identified in other brain regions, including the medial amygdala (MeA).
Katherine M. Hatcher, Leah Costanza, Alexander S. Kauffman, Shannon B. Z. Stephens, Shannon B. Z. Stephens   +4 more
doaj   +1 more source

CRISPR/Cas9-editing of KISS1 to generate pigs with hypogonadotropic hypogonadism as a castration free trait

Frontiers in Genetics, 2023
Introduction: Most male pigs are surgically castrated to avoid puberty-derived boar taint and aggressiveness. However, this surgical intervention represents a welfare concern in swine production.
Julio M. Flórez, Julio M. Flórez, Kyra Martins, Staci Solin, Jonathan R. Bostrom, Paula Rodríguez-Villamil, Felipe Ongaratto, Sabreena A. Larson, Uyanga Ganbaatar, Alexander W. Coutts, Doug Kern, Thomas W. Murphy, Eui-Soo Kim, Daniel F. Carlson, Abe Huisman, Tad S. Sonstegard, Clay A. Lents   +16 more
doaj   +1 more source

Role of Kiss1 in serotonergic modulation in the zebrafish

, 2017
KISS1/Kiss1 gene produces a neuropeptide, kisspeptin with the ability to activate its G-protein coupled receptor, GPR54 (Kiss-R), which is involved in the control of vertebrate reproduction. Previously, two forms of genes encoding kisspeptin (kiss1 and kiss2) and its respective receptor (kissr1 and kissr2) were identified in the zebrafish (Danio rerio).
Fatima Megala Nathan
  +4 more sources

Gallium-68-Labeled KISS1-54 Peptide for Mapping KISS1 Receptor via PET: Initial Evaluation in Human Tumor Cell Lines and in Tumor-Bearing Mice

Pharmaceuticals, 2023
Kisspeptins (KPs, KISS1) and their receptor (KISS1R) play a pivotal role as metastasis suppressor for many cancers. Low or lost KP expression is associated with higher tumor grade, increased metastatic potential, and poor prognosis.
Ina Israel, Gabriele Riehl, Elke Butt, Andreas K. Buck, Samuel Samnick   +4 more
doaj   +1 more source

Visualisation of Kiss1 Neurone Distribution Using a Kiss1‐CRE Transgenic Mouse [PDF]

Journal of Neuroendocrinology, 2016
Kisspeptin neuropeptides are encoded by the Kiss1 gene and play a critical role in the regulation of the mammalian reproductive axis. Kiss1 neurones are found in two locations in the rodent hypothalamus: one in the arcuate nucleus (ARC) and another in the RP3V region, which includes the anteroventral periventricular nucleus (AVPV).
Yeo, SH, Kyle, V, Morris, PG, Jackman, S, Sinnett-Smith, LC, Schacker, M, Chen, C, Colledge, W. H.   +7 more
openaire   +4 more sources

AVPV Kiss1 neuron-specific knockdown of purinergic P2X2 receptor suppresses LH surge and ovulation in Kiss1-Cre rats

The Journal of Reproduction and Development
Ovulation disorders are a major cause of low pregnancy rates and infertility in humans and livestock. Kisspeptin neurons located in the anteroventral periventricular nucleus (AVPV) are responsible for the generation of the gonadotropin-releasing hormone (
Safiullah HAZIM, Shunsuke SEKI, Ryoya YABUSHITA, Mayuko NAGAE, Hitomi TSUCHIDA, Masumi HIRABAYASHI, Yoshihisa UENOYAMA, Hiroko TSUKAMURA, Naoko INOUE   +8 more
doaj   +3 more sources

GnRH-Deficient Phenotypes in Humans and Mice With Heterozygous Variants in KISS1/Kiss1 [PDF]

Obstetrical & Gynecological Survey, 2011
KISS1 is a candidate gene for GnRH deficiency.Our objective was to identify deleterious mutations in KISS1.DNA sequencing and assessment of the effects of rare sequence variants (RSV) were conducted in 1025 probands with GnRH-deficient conditions.Fifteen probands harbored 10 heterozygous RSV in KISS1 seen in less than 1% of control subjects.
Chan YM, Broder-Fingert S, Paraschos S, Lapatto R, Au M, Hughes V, Bianco SD, Min L, Plummer L, Cerrato F, De Guillebon A, Wu IH, Wahab F, Dwyer A, Kirsch S, Quinton R, Cheetham T, Ozata M, Ten S, Chanoine JP, Pitteloud N, Martin KA, Schiffmann R, Van der Kamp HJ, Nader S, Hall JE, Kaiser UB, Seminara SB   +27 more
openaire   +3 more sources

Inducible Kiss1 knockdown in the hypothalamic arcuate nucleus suppressed pulsatile secretion of luteinizing hormone in male mice

The Journal of Reproduction and Development, 2020
Accumulating evidence suggests that kisspeptin-GPR54 signaling is indispensable for gonadotropin-releasing hormone (GnRH)/gonadotropin secretion and consequent reproductive functions in mammals. Conventional Kiss1 knockout (KO) mice and rats are reported
Shiori MINABE, Sho NAKAMURA, Eri FUKUSHIMA, Marimo SATO, Kana IKEGAMI, Teppei GOTO, Makoto SANBO, Masumi HIRABAYASHI, Junko TOMIKAWA, Takuya IMAMURA, Naoko INOUE, Yoshihisa UENOYAMA, Hiroko TSUKAMURA, Kei-Ichiro MAEDA, Fuko MATSUDA   +14 more
doaj   +1 more source