Results 21 to 30 of about 8,330 (205)
Transcriptomic Profiling of Hypothalamic Kiss1 Neurons [PDF]
, 2021 Kisspeptins, peptide products of the Kiss1 gene, are critical players in the reproductive function, particularly as major upstream neuroendocrine regulators of the Hypothalamic-Pituitary-Gonadal (HPG) axis.
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Evolutionary insights into the steroid sensitive kiss1 and kiss2 neurons in the vertebrate brain
Frontiers in Endocrinology, 2012 Kisspeptin was originally found as a peptide product of Kiss1gene and is now supposed to be an essential central regulator of reproduction in mammals. However, there is now a growing body of evidence to suggest that kiss2, the paralogous gene for kiss1 ...
Shinji eKanda, Yoshitaka eOka
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KISS1 Suppresses Apoptosis and Stimulates the Synthesis of E2 in Porcine Ovarian Granulosa Cells
Animals, 2019 Previous studies have strongly recommended that KISS-1 metastasis suppressor (KISS1) plays an essential gatekeeper of the initiation of reproductive maturation in mammals.
Xiaoping Xin +8 more
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KISS1 Metastasis Suppression and Emergent Pathways
Clinical & Experimental Metastasis, 2003 Metastatic disease is the most critical impediment to cancer patient survival. However, comparatively little is known concerning the intricate pathways which govern the complex phenotypes associated with metastasis.
Harms, John F. +2 more
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Role of Kiss1 in serotonergic modulation in the zebrafish
, 2017 KISS1/Kiss1 gene produces a neuropeptide, kisspeptin with the ability to activate its G-protein coupled receptor, GPR54 (Kiss-R), which is involved in the control of vertebrate reproduction.
Nathan , Fatima Megala (3770320)
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The Journal of Reproduction and Development, 2020 The present study aimed to evaluate whether novel conditional kisspeptin neuron-specific Kiss1 knockout (KO) mice utilizing the Cre-loxP system could recapitulate the infertility of global Kiss1 KO models, thereby providing further evidence for the ...
Kana IKEGAMI +15 more
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Inactivating KISS1 Mutation and Hypogonadotropic Hypogonadism [PDF]
Obstetrical & Gynecological Survey, 2012 Gonadotropin-releasing hormone (GnRH) is the central regulator of gonadotropins, which stimulate gonadal function. Hypothalamic neurons that produce kisspeptin and neurokinin B stimulate GnRH release. Inactivating mutations in the genes encoding the human kisspeptin receptor (KISS1R, formerly called GPR54), neurokinin B (TAC3), and the neurokinin B ...
Topaloglu, A. Kemal +9 more
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Dax1 modulates ERα-dependent hypothalamic estrogen sensing in female mice
Nature Communications, 2023 Coupling the release of pituitary hormones to the developmental stage of the oocyte is essential for female fertility. It requires estrogen to restrain kisspeptin (KISS1)-neuron pulsatility in the arcuate hypothalamic nucleus, while also exerting a surge-
Jose M. Ramos-Pittol +14 more
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Serum Kisspeptin Level in normal pregnancy and preeclampsia with and without obesity [PDF]
Zagazig University Medical Journal, 2021 Background:kisspeptin(kiss1) is a hypothalamic neuropeptide, expressed also peripherally in the placental trophoblast, pancreatic cells, liver and adipose tissue suggesting its role in regulating metabolic homeostasis as well as normal fetal implantation
ali asalah +4 more
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Frontiers in Oncology, 2023 Metastatic dissemination is still one of the major causes of death of melanoma’s patients. KiSS1 is a metastasis suppressor originally identified in melanoma cells, known to play an important physiological role in mammals’ development and puberty. It has
Carlotta Guzzetti +7 more
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