Results 31 to 40 of about 8,330 (205)
Transcriptional regulation of the human KiSS1 gene [PDF]
Molecular and Cellular Endocrinology, 2011 Kisspeptin, the product of the KiSS1 gene, has emerged as a key component of the mechanism by which the hypothalamus controls puberty and reproductive development. It does so by stimulating the secretion of gonadotropin releasing hormone (GnRH). Little is known about the transcriptional control of the KiSS1 gene.
Johanna K, Mueller +8 more
openaire +2 more sources
Altered placental expression of kisspeptin and its receptor in pre-eclampsia [PDF]
, 2012 Kisspeptin, originally identified as metastatin, important in preventing cancer metastasis, has more recently been shown to be important in pregnancy.
Williams, Paula Juliet +3 more
core +1 more source
Novel insights into the metabolic action of Kiss1 neurons [PDF]
Endocrine Connections, 2020 Kiss1 neurons are essential regulators of the hypothalamic–pituitary–gonadal (HPG) axis by regulating gonadotropin-releasing hormone (GnRH) release. Compelling evidence suggests that Kiss1 neurons of the arcuate nucleus (Kiss1 ARC ), recently identified as the hypothalamic GnRH pulse ...
Rajae Talbi, Victor M Navarro
openaire +2 more sources
Upregulated UHRF1 promotes bladder cancer cell invasion by epigenetic silencing of KiSS1. [PDF]
PLoS ONE, 2014 Ubiquitin-like with PHD and RING finger domains 1 (UHRF1), as an epigenetic regulator, plays important roles in the tumorigenesis and cancer progression.
Yu Zhang +7 more
doaj +1 more source
Association of the KiSS1 gene with litter size in Cyprus and Iraqi black goats [PDF]
Veterinary World, 2021 Aim: The study investigated the genetic polymorphism of the kisspeptin (KiSS1) gene and its relationship with litter size in Cyprus and Iraqi black goats.
M. A. Rahawy +1 more
doaj +1 more source
Scientific Reports, 2023 The gonadotropin-releasing hormone (GnRH) pulse and surge are considered to be generated by arcuate kisspeptin/neurokinin B/dynorphin A (KNDy) neurons and anteroventral periventricular nucleus (AVPV) kisspeptin neurons, respectively, in female rodents ...
Mayuko Nagae +13 more
doaj +1 more source
EGF stimulates human trophoblast cell invasion by downregulating ID3-mediated KISS1 expression
Cell Communication and Signaling, 2021 Background During pregnancy, trophoblast cell invasion needs to be finely controlled. Aberrant trophoblast cell invasion is associated with placental diseases.
Lanlan Fang +7 more
doaj +1 more source
Estradiol Regulation of Kiss1 Neurons [PDF]
, 2018 Kisspeptin, encoded by the Kiss1 gene, is required for reproductive function. There are several distinct Kiss1 populations in the brain, and how these kisspeptin neurons are regulated is still not fully understood.
Liaw, Reanna Beverly
core +1 more source
STAT4 targets KISS1 to promote the apoptosis of ovarian granulosa cells
Journal of Ovarian Research, 2020 Background In mammals, it is known that the estradiol-17β (E2) is mainly synthetized in ovarian granulosa cells (GCs), and the excessive apoptosis of GCs induces the follicular atresia.
Yao Jiang +6 more
doaj +1 more source
Clinical and Biological Significance of KISS1 Expression in Prostate Cancer [PDF]
, 2012 For men in the United States, prostate cancer (PCa) is the most frequent malignancy and the second leading cause of cancer mortality. The metastatic spread of PCa is responsible for most deaths related to PCa.
Wang, Honghe +7 more
core +1 more source