Results 31 to 40 of about 8,886 (197)
Upregulated UHRF1 promotes bladder cancer cell invasion by epigenetic silencing of KiSS1. [PDF]
PLoS ONE, 2014 Ubiquitin-like with PHD and RING finger domains 1 (UHRF1), as an epigenetic regulator, plays important roles in the tumorigenesis and cancer progression.
Yu Zhang +7 more
doaj +1 more source
Dax1 modulates ERα-dependent hypothalamic estrogen sensing in female mice
Nature Communications, 2023 Coupling the release of pituitary hormones to the developmental stage of the oocyte is essential for female fertility. It requires estrogen to restrain kisspeptin (KISS1)-neuron pulsatility in the arcuate hypothalamic nucleus, while also exerting a surge-
Jose M. Ramos-Pittol +14 more
doaj +1 more source
Sex-specific pubertal and metabolic regulation of Kiss1 neurons via Nhlh2
eLife, 2021 Hypothalamic Kiss1 neurons control gonadotropin-releasing hormone release through the secretion of kisspeptin. Kiss1 neurons serve as a nodal center that conveys essential regulatory cues for the attainment and maintenance of reproductive function ...
Silvia Leon +11 more
doaj +1 more source
Association of the KiSS1 gene with litter size in Cyprus and Iraqi black goats [PDF]
Veterinary World, 2021 Aim: The study investigated the genetic polymorphism of the kisspeptin (KiSS1) gene and its relationship with litter size in Cyprus and Iraqi black goats.
M. A. Rahawy +1 more
doaj +1 more source
Scientific Reports, 2023 The gonadotropin-releasing hormone (GnRH) pulse and surge are considered to be generated by arcuate kisspeptin/neurokinin B/dynorphin A (KNDy) neurons and anteroventral periventricular nucleus (AVPV) kisspeptin neurons, respectively, in female rodents ...
Mayuko Nagae +13 more
doaj +1 more source
Novel insights into the metabolic action of Kiss1 neurons [PDF]
Endocrine Connections, 2020 Kiss1 neurons are essential regulators of the hypothalamic–pituitary–gonadal (HPG) axis by regulating gonadotropin-releasing hormone (GnRH) release. Compelling evidence suggests that Kiss1 neurons of the arcuate nucleus (Kiss1 ARC ), recently identified as the hypothalamic GnRH pulse ...
Rajae Talbi, Victor M Navarro
openaire +3 more sources
EGF stimulates human trophoblast cell invasion by downregulating ID3-mediated KISS1 expression
Cell Communication and Signaling, 2021 Background During pregnancy, trophoblast cell invasion needs to be finely controlled. Aberrant trophoblast cell invasion is associated with placental diseases.
Lanlan Fang +7 more
doaj +1 more source
, 2023 Introduction: Most male pigs are surgically castrated to avoid puberty-derived boar taint and aggressiveness. However, this surgical intervention represents a welfare concern in swine production.
Uyanga Ganbaatar (14325111) +15 more
core +1 more source
Sexually dimorphic gene expression and neurite sensitivity to estradiol in fetal arcuate Kiss1 cells [PDF]
, 2020 International audienceKiss1 neurons of the arcuate (ARC) nucleus form an interconnected network of cells that communicate via neurokinin B (encoded by Tac2) and its receptor (encoded by Tacr3) and play key roles in the control of the reproductive axis ...
Poissenot, Kevin +7 more
core +2 more sources
KiSS1 inhibits growth and invasion of osteosarcoma cells through inhibition of the MAPK pathway
European Journal of Histochemistry, 2013 As a metastasis suppressor, KiSS1 has been implicated in numerous human cancers. However, recent studies have demonstrated that KiSS1 promotes tumor growth and metastasis in breast cancer, and it is unclear about the expression and function of KiSS1 in ...
Y. Zhang +5 more
doaj +1 more source