Results 51 to 60 of about 8,886 (197)

Mapping neuronal inputs to Kiss1 neurons in the arcuate nucleus of the mouse.

open access: yesPLoS ONE, 2019
The normal function of the mammalian reproductive axis is strongly influenced by physiological, metabolic and environmental factors. Kisspeptin neuropeptides, encoded by the Kiss1 gene, are potent regulators of the mammalian reproductive axis by ...
Shel-Hwa Yeo   +4 more
doaj   +1 more source

A dual fluorescence reporter system for high throughput screening of effectors of Kiss1 gene expression

open access: yesFEBS Open Bio, 2018
Kisspeptin is a multifunctional peptide encoded by the Kiss1 gene that plays critical roles in mammalian puberty onset modulation and fertility maintenance in the hypothalamus.
Xiaoning Li   +7 more
doaj   +1 more source

The metastasis suppressor KISS1 is an intrinsically disordered protein slightly more extended than a random coil. [PDF]

open access: yesPLoS ONE, 2017
The metastasis suppressor KISS1 is reported to be involved in the progression of several solid neoplasias, making it a promising molecular target for controlling their metastasis.
Alain Ibáñez de Opakua   +8 more
doaj   +1 more source

Toxic Effects of Bisphenol A and Its Analogs on Ovarian Structure and Function: A Narrative Review of Ovary‐Focused Studies

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) is a widely used industrial chemical found in polycarbonate plastics and epoxy resins and is recognized for its endocrine‐disrupting properties. Human exposure is common due to its presence in food packaging and everyday products. As BPA use has been restricted, structurally similar compounds such as BPS, BPB, BPAF, and BADGE
Nurbanu Zengin   +4 more
wiley   +1 more source

Molecular cloning and characterization of KISS1 promoter and effect of KISS1 gene mutations on litter size in the goat

open access: yesGenetics and Molecular Research, 2013
Kisspeptins, the product of the KISS1 gene, play an essential role in the regulation of reproductive functions, acting primarily at the hypothalamic level of the gonadotropic axis. We detected polymorphisms of the goat KISS1 gene in 723 individuals from three goat breeds (Xinong Saanen, Guanzhong, and Boer) by DNA pooling, PCR-RFLP, and DNA sequencing ...
X P, An   +10 more
openaire   +2 more sources

PGR does not regulate Kiss1 gene expression.

open access: yes, 2016
Kiss1 mRNA expression level in 6-month-old WT (n = 9) and Kiss1-PgrKO (n = 4) mice.
Andrew Wolfe (703417)   +9 more
core   +1 more source

CRE-dependent PRV-GFP activation in Kiss1 neurons.

open access: yes, 2019
Stereotaxic delivery of the PRVINTRO virus into the arcuate (ARC) region of mice was associated with GFP expression only in Kiss1-CRE mice. PRVINTRO driven GFP expression (arrowed) at 24 h after delivery was restricted to Kiss1 neurons (A) but at 48 h ...
Clemence Blouet (6519428)   +4 more
core   +1 more source

Advent of NK3R Antagonists for the Treatment of Menopausal Hot Flushes: A Narrative Review

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT The menopause transition is marked by symptoms predominantly attributed to declining oestrogen levels. Approximately 80% of women experience associated symptoms, and 25% experience severe symptoms. The commonest are vasomotor symptoms (VMS), collectively referring to hot flushes and/or night sweats.
Aaran H. Patel   +5 more
wiley   +1 more source

Novel Insight into the Role of the Kiss1/GPR54 System in Energy Metabolism in Major Metabolic Organs

open access: yesCells, 2022
The Kiss1/GPR54 system is a multifunctional genetic system with an essential role in regulating energy balance and metabolic homeostasis. In the mammalian hypothalamus, two major populations of neurons, the rostral periventricular region of the third ...
Xuehan Li, Chunyu Liang, Yi Yan
doaj   +1 more source

Identification of MEF2A, MEF2C, and MEF2D interactomes in basal and Fsk‐stimulated mouse MA‐10 Leydig cells

open access: yesAndrology, Volume 14, Issue 8, Page 2401-2418, November 2026.
Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos   +4 more
wiley   +1 more source

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