Results 51 to 60 of about 8,330 (205)

Reversibility and safety of KISS1 metastasis suppressor gene vaccine in immunocastration of ram lambs [PDF]

open access: yesAsian-Australasian Journal of Animal Sciences, 2018
Objective The aim of this study was to investigate the reversibility and safety of KISS1 metastasis suppressor (KISS1) gene vaccine in immunocastration. Methods Six eight-week old ram lambs were randomly divided into vaccinated and control groups.
Yan-Guo Han   +8 more
doaj   +1 more source

Toxic Effects of Bisphenol A and Its Analogs on Ovarian Structure and Function: A Narrative Review of Ovary‐Focused Studies

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) is a widely used industrial chemical found in polycarbonate plastics and epoxy resins and is recognized for its endocrine‐disrupting properties. Human exposure is common due to its presence in food packaging and everyday products. As BPA use has been restricted, structurally similar compounds such as BPS, BPB, BPAF, and BADGE
Nurbanu Zengin   +4 more
wiley   +1 more source

Proprotein convertases are required for KISS1 processing.

open access: yes, 2014
A. Amino acid sequence of KISS1 showing three predicted PC cleavage sites − RK, RR and KR in bold. Note: DYKDDDDK at position 68 is the FLAG epitope tag used for several of the studies described in this manuscript. B. Treatment of C8161.9, MelJuSo, HeLa,
Danny R. Welch (160661)   +4 more
core   +1 more source

A dual fluorescence reporter system for high throughput screening of effectors of Kiss1 gene expression

open access: yesFEBS Open Bio, 2018
Kisspeptin is a multifunctional peptide encoded by the Kiss1 gene that plays critical roles in mammalian puberty onset modulation and fertility maintenance in the hypothalamus.
Xiaoning Li   +7 more
doaj   +1 more source

Advent of NK3R Antagonists for the Treatment of Menopausal Hot Flushes: A Narrative Review

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT The menopause transition is marked by symptoms predominantly attributed to declining oestrogen levels. Approximately 80% of women experience associated symptoms, and 25% experience severe symptoms. The commonest are vasomotor symptoms (VMS), collectively referring to hot flushes and/or night sweats.
Aaran H. Patel   +5 more
wiley   +1 more source

The metastasis suppressor KISS1 is an intrinsically disordered protein slightly more extended than a random coil. [PDF]

open access: yesPLoS ONE, 2017
The metastasis suppressor KISS1 is reported to be involved in the progression of several solid neoplasias, making it a promising molecular target for controlling their metastasis.
Alain Ibáñez de Opakua   +8 more
doaj   +1 more source

Novel Insight into the Role of the Kiss1/GPR54 System in Energy Metabolism in Major Metabolic Organs

open access: yesCells, 2022
The Kiss1/GPR54 system is a multifunctional genetic system with an essential role in regulating energy balance and metabolic homeostasis. In the mammalian hypothalamus, two major populations of neurons, the rostral periventricular region of the third ...
Xuehan Li, Chunyu Liang, Yi Yan
doaj   +1 more source

Identification of MEF2A, MEF2C, and MEF2D interactomes in basal and Fsk‐stimulated mouse MA‐10 Leydig cells

open access: yesAndrology, EarlyView.
Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos   +4 more
wiley   +1 more source

Estradiol Priming Potentiates the Kisspeptin-Induced Release of LH in Ovariectomized Cows

open access: yesAnimals, 2021
The present study examined whether priming with estradiol benzoate (EB) for 12 h increased both the peak and duration of LH release in response to kisspeptin (KISS1, KP) in cows.
Gustavo Guerino Macedo   +4 more
doaj   +1 more source

Analisis Genetik Gen KiSS1 pada Kambing Berdasarkan Sekuen DNA GenBank [PDF]

open access: yes, 2020
Gen KiSS1 merupakan kandidat gen yang berpengaruh pada sifat reproduksi kambing. Tujuan penelitian ini untuk identifikasi SNP, perubahan asam amino dan phylogenetic tree kambing berdasarkan data sekuen DNA gen KiSS1 GenBank.
Guntur, Achmad   +3 more
core  

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