Results 61 to 70 of about 8,886 (197)
UHRF1 increases bladder cancer cell invasion by inhibiting KiSS1.
, 2014 (A and B) RT4 cells were treated with KiSS1-siRNA and invasion assay was performed after KiSS1 knockdown. Representative figures of each experiment are shown.
Xin Zheng (104081) +7 more
core +1 more source
Anteroventral Periventricular Kiss1 Gene Expression is Regulated by Estradiol through Estrogen Response Elements [PDF]
, 2020 In females, estrogen signaling is necessary for coordinating ovulation and the menstrual cycle. KISS1, a gene expressed by kisspeptin neurons and critical for reproduction, is positively and negatively regulated by 17β-estradiol (E2), an endogenous ...
Chou, Teresa
core +1 more source
Estradiol Priming Potentiates the Kisspeptin-Induced Release of LH in Ovariectomized Cows
Animals, 2021 The present study examined whether priming with estradiol benzoate (EB) for 12 h increased both the peak and duration of LH release in response to kisspeptin (KISS1, KP) in cows.
Gustavo Guerino Macedo +4 more
doaj +1 more source
Journal of Neuroendocrinology, Volume 38, Issue 11, November 2026.Abstract The pattern of gonadotropin‐releasing hormone (GnRH) release controls reproduction in vertebrates and is regulated by feedback from the gonads. Evidence is accumulating that steroid‐sensitive hypothalamic arcuate kisspeptin–neurokinin B–dynorphin (KNDy) neurons drive GnRH pulses.
R. Anthony DeFazio +4 more
wiley +1 more source
Advanced Healthcare Materials, Volume 15, Issue 39, 23 October 2026.Living donor heart valves offer superior durability for pediatric patients but trigger immune rejection. Lentiviral delivery of viral immune‐evasion genes US2 and Serpin b9 into donor valve cells and valve tissue suppresses HLA expression, reduces PBMC clustering and cytotoxic killing, and induces transcriptional immune‐tolerance programs, paving the ...
Abraham van Wijk +11 more
wiley +1 more source
Cell Biochemistry and Function, Volume 44, Issue 10, October 2026.ABSTRACT Melanoma is a type of skin cancer associated with the uncontrolled growth of melanocytes, the pigment‐producing cells. This type of skin cancer continues to be a major concern owing to its strong tendency to spread. Melanoma progression is influenced by the activation of various signalling pathways, such as PI3K/AKT/mTOR, MAPK/ERK, and Wnt/β ...
Tivoli Visser +3 more
wiley +1 more source
Proprotein convertases are required for KISS1 processing.
, 2014 A. Amino acid sequence of KISS1 showing three predicted PC cleavage sites − RK, RR and KR in bold. Note: DYKDDDDK at position 68 is the FLAG epitope tag used for several of the studies described in this manuscript. B. Treatment of C8161.9, MelJuSo, HeLa,
Danny R. Welch (160661) +4 more
core +1 more source
eLife, 2018 The neuropeptides tachykinin2 (Tac2) and kisspeptin (Kiss1) in hypothalamic arcuate nucleus Kiss1 (Kiss1ARH) neurons are essential for pulsatile release of GnRH and reproduction.
Jian Qiu +7 more
doaj +1 more source
Endocrine Connections, 2022 Kisspeptin system was shown to be a key factor in mediating social stress and reproduction. Yellowtail clownfish, Amphiprion clarkii, is a hermaphrodite fish, whose sex determination and gonadal development are affected by the social status of ...
Yan-yu Zhang +7 more
doaj +1 more source
Journal of Neuroendocrinology, Volume 38, Issue 10, October 2026.Abstract To describe clinical presentation and genetic findings in a cohort of infants with congenital hypogonadotropic hypogonadism (CHH) diagnosed before 2 years of age. From a large cohort of patients who underwent next‐generation sequencing (NGS) for CHH between 2019 and 2025, we identified all patients tested at ≤2 years of age.
Karine Aouchiche +16 more
wiley +1 more source