Results 81 to 90 of about 2,756 (195)

Sexual Dimorphism in Kisspeptin and Kiss1R in the Ventrolateral Periaqueductal Gray [PDF]

, 2021
Chronic pain manifests as a debilitating pathological state that affects up to 10% of the global population. Previous investigations revealed a disproportionate distribution of pain experience between sexes with females reporting a higher prevalence of ...
Hernandez, Jacqueline
core  

Metabolic Reprogramming in Recurrent Spontaneous Abortion: Key Biomarkers Identification and Diagnostic Model Development

IET Systems Biology, Volume 20, Issue 1, January/December 2026.
This study aims to identify differentially expressed genes associated with metabolic reprogramming in RSA. Using both bulk and single‐cell RNA sequencing datasets from the Gene Expression Omnibus (GEO), we constructed a machine learning‐based diagnostic model and investigated cell‐type‐specific immune‐metabolic crosstalk.
Fan Wu, Chuanmei Qin, Xiaowei Wei, Qian Li, Yi Yuan, Weihong Zeng, Yi Lin   +6 more
wiley   +1 more source

A novel homozygous splice acceptor site mutation of KISS1R in two siblings with normosmic isolated hypogonadotropic hypogonadism

, 2010
Context: Loss-of-function mutations of the kisspeptin-1 receptor gene, KISS1R, have been identified in patients with normosmic isolated hypogonadotropic hypogonadism (nIHH).
Miami School of Medicine, Sao Paulo State, JORGE, A., BIANCO, S. D., A. C. Latronico, Mendonca, B B, M. G. Teles, Costa, E M, G. Guerra-Junior, BENEDUZZI, D., BAPTISTA, M. T., S. D. Bianco, E. M. Costa, Teles, M G, MENDONCA, B. B., De Castro, M, Harvard, A. Jorge, Trarbach, E B, S. D. Noel, D. Beneduzzi, Guerra-Junior, G, GUERRA-JUNIOR, G., M. T. Baptista, Castro, M De, COSTA, E. M., TRARBACH, E. B., Noel, S D, NOEL, S. D., Mukherjee, A, TELES, M. G., Beneduzzi, D, Baptista, M T, Jorge, A, Bianco, S D, Kaiser, U B, Latronico, A C, E. B. Trarbach, MUKHERJEE, A., A. Mukherjee, U. B. Kaiser, KAISER, U. B., B. B. Mendonca, LATRONICO, A. C., CASTRO, M. De, M. De Castro   +45 more
core   +1 more source

Studies of the mouse Kiss1r promoter and its regulation by estrogen [PDF]

, 2011
Kisspeptin, and its G-protein-coupled receptor, Kiss1r, participate in the regulation of gonadotropin-releasing hormone (GnRH) secretion, which regulates feedback pathways that control reproductive hormones.
Kose, Lara Tamar
core  

KISS1 and KISS1R are variably expressed in MSCs, OPCs, and tumor cell lines.

, 2016
Protein expression of the kisspeptin precursor KISS1 and the receptor KISS1R was investigated in primary MSCs (A) and OPCs (B). Specificity of the KISS1R antibody was confirmed by the addition of a blocking antigen (C).
Lorenz C. Hofbauer (759669), Sanjay Tiwari (1669654), Norbert Schütze (306441), Franz Jakob (133384), Claus C. Glüer (347285), Robert J. Tower (2736013), Andreas Brandl (668766), Marc Müller (2736016), Regina Ebert (133381), Andreas Beilhack (63291), Julia Dotterweich (2736019)   +10 more
core   +1 more source

Immunohistochemical study of KiSS1 and KiSS1R expression in human primary breast cancer: Association with breast cancer receptor status, proliferation markers and clinicopathological features [PDF]

, 2015
Recent studies have raised doubts about the protective role of KiSS1/KiSS1R in breast malignancy progression. However, the role of the KiSS1/KiSS1R system in primary breast cancer remains largely unknown.
Milewski, Robert, Kozlowski, Leszek, Koda, Mariusz, Wolczynsk, Slawomir, Jarzabek, Katarzyna   +4 more
core   +1 more source

Kallmann Syndrome in a 30‐Year‐Old Female With Primary Infertility: A Case Report

Case Reports in Obstetrics and Gynecology, Volume 2026, Issue 1, 2026.
Kallmann syndrome (KS) is a rare genetic disorder characterized by hypogonadotropic hypogonadism and anosmia. This case report highlights a 30‐year‐old woman with KS who presented with secondary amenorrhea and uterine hypoplasia after repeated use of combined oral contraceptives (COCs).
Arry Soryadharma, Mulyanusa Amarullah Ritonga, Wiryawan Permadi, Manvinder Singh   +3 more
wiley   +1 more source

Pancancer Analyses of KISS1 as a Potential Biomarker for Tumor Metastasis and Immunotherapy and Therapeutic Target for Breast Cancer

International Journal of Genomics, Volume 2026, Issue 1, 2026.
Emerging evidence highlights the pivotal role of KISS1 in cancer metastasis; however, there remains a dearth of pancancer analyses, particularly concerning immunotherapy. Here, we conducted a comprehensive investigation of KISS1 across various cancers, with a specific focus on breast cancer, using TCGA and GTEx datasets.
Chunbiao Wu, Hao Jiang, Wei Xu, Bo Li, Hao Zhang, Long Zhang, Zhenxi Li, Jianru Xiao, Pengpeng Zhang   +8 more
wiley   +1 more source

Expresión gestacional y postparto del receptor Kiss1R en el útero de rata Wistar [PDF]

, 2021
"Durante los recambios celulares úterinos que se dan a lo largo del embarazo diversos factores que coadyuvan al inicio, desarrollo y término de la gestación.
Maqueda Bautista, Diego Jesús
core  

The Concise Guide to PHARMACOLOGY 2025/26: G protein‐coupled receptors

British Journal of Pharmacology, Volume 182, Issue S1, Page S24-S151, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Anthony P. Davenport, Eamonn Kelly, Alasdair J. Gibb, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Maria Pia Abbracchio, George R. Abraham, Alexander Agoulnik, Wayne Alexander, Khaled Al‐hosaini, Magnus Bäck, Jillian G. Baker, Nicholas M. Barnes, Ross Bathgate, Jean‐Martin Beaulieu, Annette G. Beck‐Sickinger, Maik Behrens, Kirstie A. Bennett, Kenneth E. Bernstein, Bernhard Bettler, Nigel J. M. Birdsall, Victoria A. Blaho, Pascal Bonaventure, Francois Boulay, Corinne Bousquet, Hans Bräuner‐Osborne, Andrew J. Brown, Geoffrey Burnstock, Marta Busnelli, Girolamo Caló, Vanni Caruso, Justo P. Castaño, Kevin J. Catt, Stefania Ceruti, Paul Chazot, Nan Chiang, Bice Chini, Arthur Christopoulos, Jerold Chun, Antonia Cianciulli, Olivier Civelli, Lucie H. Clapp, Réjean Couture, Helen M. Cox, Zsolt Csaba, Claes Dahlgren, Frank M. Dautzenberg, Gordon Dent, Steven D. Douglas, Pascal Dournaud, Margarita L. Dubocovich, Satoru Eguchi, Emanuel Escher, Edward J. Filardo, Tung Fong, Huamei Fu Forsman, Marta Fumagalli, Raul R. Gainetdinov, Michael L. Garelja, Marc de Gasparo, Florence Gbahou, Craig Gerard, Marvin Gershengorn, Michelle Glass, David E. Gloriam, Fernand Gobeil, Theodore L. Goodfriend, Cyril Goudet, Lukas Grätz, Karen J. Gregory, Christian Gruber, Andrew L. Gundlach, Jörg Hamann, Julien Hanson, Deborah S. Hartman, Richard L. Hauger, Debbie L. Hay, Akos Heinemann, Laura Heitman, Deron R. Herr, Morley D. Hollenberg, Nicholas D. Holliday, Birgitte Holst, Mastgugu Horiuchi, Daniel Hoyer, László Hunyady, Ahsan Husain, Adriaan P. IJzerman, Tadashi Inagami, Paul A. Insel, Kenneth A. Jacobson, Laura H. Jacobson, Robert T. Jensen, Ralf Jockers, Deepa Jonnalagadda, Sadashiva Karnik, Klemens Kaupmann, Jacqueline Kemp, Charles Kennedy, Yasuyuki Kihara, Julia Kinsolving, Takio Kitazawa, Pawel Kozielewicz, Hans‐Jürgen Kreienkamp, Jyrki P. Kukkonen, Luxmichan Laishram, Tobias Langenhan, Christopher J. Langmead, Dan Larhammar, Katie Leach, Davide Lecca, John D. Lee, Susan E. Leeman, Jérôme Leprince, Rob Leurs, Xaria X. Li, Ines Liebscher, Stephen J. Lolait, Amelie Lupp, Robyn Macrae, Janet J. Maguire, Davide Malfacini, Maurice Manning, Davide Marangon, Kirill Martemyanov, Jean Mazella, Craig A. McArdle, Shlomo Melmed, Martin C. Michel, Laurence J. Miller, Vincenzo Mitolo, Bernard Mouillac, Christa E. Müller, Philip M. Murphy, Jean‐Louis Nahon, Richard R. Neubig, Tony Ngo, Xavier Norel, Duuamene Nyimanu, Anne‐Marie O’Carroll, Stefan Offermanns, Maria Antonietta Panaro, Marc Parmentier, Nicole Perry‐Hauser, Roger G. Pertwee, Jean‐Philippe Pin, Eric R. Prossnitz, Helena Chengxue Qin, Mark Quinn, Stefano Raffaele, Rithwik Ramachandran, Manisha Ray, Rainer K. Reinscheid, Alejandro Romeral Buzón, Philippe Rondard, Mette M. Rosenkilde, G. Enrico Rovati, Chiara Ruzza, Gareth J. Sanger, Nicole Scholz, Torsten Schöneberg, Gunnar Schulte, Stefan Schulz, Deborah L. Segaloff, Charles N. Serhan, Arun K. Shukla, Khuraijam Dhanachandra Singh, Craig M. Smith, Nicola J. Smith, Claudia Stäubert, Leigh A. Stoddart, Yukihiko Sugimoto, Roger Summers, Valerie P. Tan, David M. Thal, Walter ( Wally) Thomas, Pieter B. M. W. M. Timmermans, Kalyan Tirupula, Lawrence Toll, Giovanni Tulipano, Hamiyet Unal, Thomas Unger, Celine Valant, Patrick Vanderheyden, David Vaudry, Hubert Vaudry, Joseph G. Verbalis, Jean‐Pierre Vilardaga, Christopher S. Walker, Ji Ming Wang, Donald T. Ward, Hans‐Jürgen Wester, Gary B. Willars, Tom Lloyd Williams, Trent M. Woodruff, Huixian Wu, Cheng Yang, Chengcan Yao, Richard D. Ye, Nathan Zaidman   +206 more
wiley   +1 more source