Results 111 to 120 of about 2,975 (220)

Temporal dynamics and diagnostic utility of kisspeptin and neudesin across the menstrual cycle in polycystic ovary syndrome

Middle East Fertility Society Journal
Background Polycystic Ovary Syndrome (PCOS) is a complex endocrine disorder that is characterized by neuroendocrine dysfunction. While gonadotropin dysregulation is well established, the roles of neuropeptides, such as kisspeptin and neudesin, remain ...
Ammar Jabbar Taama, Haider Abd Jabbar Alammar   +1 more
doaj   +1 more source

Reproduction, Smell and Neurodevelopmental disorders: Genetic defects in different hypogonadotropic hypogonadal syndromes.

Frontiers in Endocrinology, 2014
The neuroendocrine control of reproduction in mammals is governed by a neural hypothalamic network of nearly 1500 gonadotropin-releasing hormone (GnRH) secreting neurons that modulate the activity of the reproductive axis across life.
Hernan G VALDES-SOCIN, Matilde eRUBIO ALMANZA, Mariana eTOME FERNANDEZ-LADREDA, François Guillaume DEBRAY, Vincent eBOURS, Albert eBeckers   +5 more
doaj   +1 more source

Evolutionally Conserved Function of Kisspeptin Neuronal System Is Nonreproductive Regulation as Revealed by Nonmammalian Study [PDF]

, 2018
The kisspeptin neuronal system, which consists of a neuropeptide kisspeptin and its receptor Gpr54, is considered in mammals a key factor of reproductive regulation, the so-called hypothalamic–pituitary–gonadal (HPG) axis.
Akazome, Yasuhisa, Kanda, Shinji, Karigo, Tomomi, Kobayashi, Makito, Nakajo, Mikoto, Okamoto, Yoshitaka, Takahashi, Akiko, Uenoyama, Yoshihisa   +7 more
core  

Congenital Hypogonadotropic Hypogonadism and Kallmann Syndrome: Past, Present, and Future [PDF]

, 2015
The proper development and coordination of the hypothalamic-pituitary-gonadal (HPG) axis are essential for normal reproductive competence. The key factor that regulates the function of the HPG axis is gonadotrophin-releasing hormone (GnRH).
Achermann, Andersson, Au, Avbelj Stefanija, Ballabio, Boehm, Bulow, Canto, Chan, Costa-Barbosa, De Morsier, de Roux, de Roux, Ding, Dode, Falardeau, Farooqi, Fechner, Forni, Franco, Hanchate, Hu, Jackson, Kallmann, Kaplan, Kim, Kuiri-Hanninen, Laitinen, Leroy, Maestre de San Juan, Maione, Matsuo, Mayer, Meczekalski, Miraoui, Navarro, Pingault, Pinilla, Pinto, Pitteloud, Pitteloud, Quennell, Quinton, Schwanzel-Fukuda, Schwarting, Segal, Sidhoum, Sykiotis, Topaloglu, Tornberg, Vermeulen, Watanabe, Wierman, Xu, Zhao   +54 more
core   +2 more sources

Afferent Neuronal Control of Type-I Gonadotropin Releasing Hormone Neurons in the Human. [PDF]

, 2013
Understanding the regulation of the human menstrual cycle represents an important ultimate challenge of reproductive neuroendocrine research. However, direct translation of information from laboratory animal experiments to the human is often complicated ...
Hrabovszky, Erik, Liposits, Zsolt
core   +1 more source

Central precocious puberty: From genetics to treatment [PDF]

, 2018
Central precocious puberty (CPP) results from early activation of the hypothalamic - pituitary -gonadal (HPG) axis and follows the same sequence as normal puberty.
Eugster, Erica A., Schneider Aguirre, Rebecca   +1 more
core   +1 more source

Weak evidence of bright light effects on human LH and FSH [PDF]

, 2010
Background Most mammals are seasonal breeders whose gonads grow to anticipate reproduction in the spring and summer. As day length increases, secretion increases for two gonadotropins, luteinizing hormone (LH) and follicle stimulating hormone (FSH). This
Daniel F Kripke, Jeffrey A Elliott, Shawn D Youngstedt, Barbara L Parry, Richard L Hauger, Katharine M Rex   +5 more
core   +1 more source

Altered expression of kisspeptin, dynorphin, and related neuropeptides in polycystic ovary syndrome: A cross-sectional study

International Journal of Reproductive BioMedicine
Background: Since kisspeptin (KISS1) in the hypothalamus is affected by the inhibitory effect of dynorphin, it raises questions about the controlled balance of these 2 neuropeptides in women with and without polycystic ovary syndrome (PCOS).
Andon Hestiantoro, Rachellina Noor Al Maghfira, Ratna Fathmasari, Ririn Rahmala Febri, Ericko Ongko Joyo, Raden Muharam, Gita Pratama, Anom Bowolaksono   +7 more
doaj   +1 more source

Deficiency of Prdm13, a dorsomedial hypothalamus-enriched gene, mimics age-associated changes in sleep quality and adiposity [PDF]

, 2014
The dorsomedial hypothalamus (DMH) controls a number of essential physiological responses. We have demonstrated that the DMH plays an important role in the regulation of mammalian aging and longevity.
Brace, Cynthia S, Imai, Shin-ichiro, Rensing, Nick, Satoh, Akiko   +3 more
core   +2 more sources

Central regulation of food intake and reproduction

, 2011
The work described in this thesis investigates the actions of hypothalamic neuropeptides involved in the control of energy homeostasis and reproduction.
Beale, Kylie Emma Louise, Beale, Kylie Emma Louise   +1 more
core   +1 more source