Results 101 to 110 of about 1,992 (211)
Thyroid hormone and seasonal rhythmicity
Living organisms show seasonality in a wide array of functions such as reproduction, fattening, hibernation and migration. At temperate latitudes, changes in photoperiod maintain the alignment of annual rhythms with predictable changes in the environment.
Hugues eDardente +5 more
doaj +1 more source
Background Polycystic Ovary Syndrome (PCOS) is a complex endocrine disorder that is characterized by neuroendocrine dysfunction. While gonadotropin dysregulation is well established, the roles of neuropeptides, such as kisspeptin and neudesin, remain ...
Ammar Jabbar Taama +1 more
doaj +1 more source
Background Kisspeptins (Kiss) are prime players in the control of reproductive function through their regulation of gonadotropin-releasing hormone (GnRH) expression in the brain.
Selvaraj Sethu +7 more
doaj +1 more source
Hyperalgesic Activity of Kisspeptin in Mice
Background: Kisspeptin is a neuropeptide known for its role in the hypothalamic regulation of the reproductive axis. Following the recent description of kisspeptin and its 7-TM receptor, GPR54, in the dorsal root ganglia and dorsal horns of the spinal cord, we examined the role of kisspeptin in the regulation of pain sensitivity in mice.
Spampinato S +9 more
openaire +4 more sources
The neuroendocrine control of reproduction in mammals is governed by a neural hypothalamic network of nearly 1500 gonadotropin-releasing hormone (GnRH) secreting neurons that modulate the activity of the reproductive axis across life.
Hernan G VALDES-SOCIN +5 more
doaj +1 more source
Kisspeptins and kisspeptin neurons: Effects on reproductive system and hypothalamic localizations
Bu çalışmanın bir kısmı Uluslararası Katılımlı X. Ulusal Histoloji ve Embriyoloji Kongresi‘nde “Tematik Bildiri” olarak sunulmuşturKISS-1 geni (1q32) tarafından üretilen 145 aminoasitlik bir öncül proteinden türeyen ve GPR54 reseptörü üzerinden ...
core
Natural peptides displaying agonist activity on the orphan G protein-coupled receptor GPR54 were isolated from human placenta. These 54-, 14,- and 13-amino acid peptides, with a common RF-amide C terminus, derive from the product of KiSS-1, a metastasis ...
Parmentier, Marc +13 more
core +1 more source
Background: Since kisspeptin (KISS1) in the hypothalamus is affected by the inhibitory effect of dynorphin, it raises questions about the controlled balance of these 2 neuropeptides in women with and without polycystic ovary syndrome (PCOS).
Andon Hestiantoro +7 more
doaj +1 more source
Kisspeptin-10 is a potent stimulator of LH and increases pulse frequency in men [PDF]
Kisspeptins stimulate GnRH and thus gonadotropin secretion. Kisspeptin-10 is the minimal kisspeptin sequence with full intrinsic bioactivity, but it has not been studied in ...
Anderson, Richard A. +20 more
core +1 more source
Orphan G-protein-coupled receptors that have recently been paired with their cognate ligand are an often untapped resource for novel drug development.
Mead, Emma J +7 more
core +1 more source

