Results 101 to 110 of about 2,088 (213)

Increased expression of kisspeptin and GnRH forms in the brain of scombroid fish during final ovarian maturation and ovulation

Reproductive Biology and Endocrinology, 2012
Background Kisspeptins (Kiss) are prime players in the control of reproductive function through their regulation of gonadotropin-releasing hormone (GnRH) expression in the brain.
Selvaraj Sethu, Kitano Hajime, Amano Masafumi, Ohga Hirofumi, Yoneda Michio, Yamaguchi Akihiko, Shimizu Akio, Matsuyama Michiya   +7 more
doaj   +1 more source

Kisspeptin and Endometriosis—Is There a Link?

Journal of Clinical Medicine
This article presents a narrative review that explores the potential link between kisspeptin—a key regulator of the hypothalamic-pituitary-gonadal axis—and the pathogenesis of endometriosis. Kisspeptin plays a significant role in regulating reproductive functions by modulating the release of gonadotropin-releasing hormone (GnRH), which in turn ...
Blazej Meczekalski, Agata Nowicka, Stefania Bochynska, Aleksandra Szczesnowicz, Gregory Bala, Anna Szeliga   +5 more
openaire   +2 more sources

First evidence for a direct inhibitory effect of kisspeptins on LH expression in the eel, Anguilla anguilla

, 2011
International audienceThe kisspeptin system has emerged as one of the main puberty gatekeepers among vertebrates. The European eel (Anguilla anguilla) is a remarkable model due to its phylogenetical position at the basis of teleosts, and its unique life ...
H. Vaudry, Rousseau, Karine, Vaudry, Hubert, A.-G. Lafont, Dufour, Sylvie, K. Rousseau, Lafont, Anne-Gaëlle, Pasquier, Jérémy, Leprince, Jérôme, S. Dufour, J. Pasquier, J. Leprince   +11 more
core   +1 more source

Reproduction, Smell and Neurodevelopmental disorders: Genetic defects in different hypogonadotropic hypogonadal syndromes.

Frontiers in Endocrinology, 2014
The neuroendocrine control of reproduction in mammals is governed by a neural hypothalamic network of nearly 1500 gonadotropin-releasing hormone (GnRH) secreting neurons that modulate the activity of the reproductive axis across life.
Hernan G VALDES-SOCIN, Matilde eRUBIO ALMANZA, Mariana eTOME FERNANDEZ-LADREDA, François Guillaume DEBRAY, Vincent eBOURS, Albert eBeckers   +5 more
doaj   +1 more source

Hyperalgesic Activity of Kisspeptin in Mice

Molecular Pain, 2011
Background: Kisspeptin is a neuropeptide known for its role in the hypothalamic regulation of the reproductive axis. Following the recent description of kisspeptin and its 7-TM receptor, GPR54, in the dorsal root ganglia and dorsal horns of the spinal cord, we examined the role of kisspeptin in the regulation of pain sensitivity in mice.
Spampinato S, Trabucco A, Biasiotta A, Biagioni F, Cruccu G, COPANI, Agata Graziella, Colledge WH, SORTINO, Maria Angela, Nicoletti F, CHIECHIO, SANTINA   +9 more
openaire   +4 more sources

The Expression of Kisspeptins and Matrix Metalloproteinases in Extragenital Endometriosis

Biomedicines
Endometriosis is characterized by a condition where endometrial tissue grows outside the uterine cavity. The mechanisms of endometrium growth during endometriosis might be similar to the development of a tumor.
Tatiana Kleimenova, Victoria Polyakova, Natalia Linkova, Anna Drobintseva, Dmitriy Medvedev, Alexander Krasichkov   +5 more
doaj   +1 more source

Altered expression of kisspeptin, dynorphin, and related neuropeptides in polycystic ovary syndrome: A cross-sectional study

International Journal of Reproductive BioMedicine
Background: Since kisspeptin (KISS1) in the hypothalamus is affected by the inhibitory effect of dynorphin, it raises questions about the controlled balance of these 2 neuropeptides in women with and without polycystic ovary syndrome (PCOS).
Andon Hestiantoro, Rachellina Noor Al Maghfira, Ratna Fathmasari, Ririn Rahmala Febri, Ericko Ongko Joyo, Raden Muharam, Gita Pratama, Anom Bowolaksono   +7 more
doaj   +1 more source

A KiSS to remember

, 2005
The Kiss1 gene encodes a family of neuropeptides named kisspeptins, which bind to a (former orphan) G-protein-coupled receptor called GPR54. Recent investigations suggest that kisspeptins play a vital role in regulating the secretion
Clifton, Donald K., Steiner, Robert A., Popa, Simina M.   +2 more
core  

The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54

, 2001
Natural peptides displaying agonist activity on the orphan G protein-coupled receptor GPR54 were isolated from human placenta. These 54-, 14,- and 13-amino acid peptides, with a common RF-amide C terminus, derive from the product of KiSS-1, a metastasis ...
Parmentier, Marc, Brezillion, Stephane, Kotani, M., Detheux, Michel, Vandeput, F., Communi, David, Schiffmann, Serge N., Vanderwinden, Jean-Marie, Suarez Gonzalez, Nathalie, Blanpain, Cédric, Le Poul, Emmanuel, Vandenbogaerde, A., Tyldesley, R., Vassart, Gilbert   +13 more
core   +1 more source

The role of kisspeptin system in cancer biology

, 2019
Kisspeptins are a family of neuropeptides that are known to be critical in puberty initiation and ovulation. Apart from that kisspeptin derived peptides (KPs) are also known for their antimetastatic activities in several malignancies.
Syrigos, N., Koutsilieris, M., Armakolas, A., Stathaki, M., Simantiris, S., Magioris, G., Dourakis, S., Stamatiou, M.E.   +7 more
core   +1 more source