Results 221 to 230 of about 773,972 (346)

Elevated blood pressure in resting daytime-phase in A170/p62-knockout mice, a newly established obese model

, 2013
Satoshi Sakai, Eiji Warabi, Toru Yanagawa, Taizo Kimura, Kazuko Tajiri, Satoshi Homma, Keisuke Kuga, Kazutaka Aonuma, Tetsuro Ishii, Takashi Miyauchi   +9 more
openalex   +1 more source

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

Advanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu, Xue Li, Tong Wu, Dan Ji, Yugang Bai, Xuezhi Zhou   +5 more
wiley   +1 more source

Integrated multi‑omics analysis of liver metabolic dysregulation in ACE2 knockout mice. [PDF]

Int J Mol Med
Xiao S, Guo J, Yu B, Zhao S, Shang Y, Li N, Cui J, Song F, Jiang P.   +8 more
europepmc   +1 more source

3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research

Advanced Functional Materials, EarlyView.
A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram, Majd Machour, Janette Zavin, Roy Meretzki, Reut Lev‐Ari, Shulamit Levenberg   +5 more
wiley   +1 more source

Wheat-Based Protein Slows Disease Progression in Pkd1 Knockout Mice. [PDF]

Function (Oxf)
Sedaka R, Huang J, Yamaguchi S, Hallit E, Moran-Reyna A, Hsu JS, Lovelady C, Fujihashi A, Sako M, Kasztan M, Benavides G, Wilson L, Darley-Usmar V, Barnes S, Saigusa T.   +14 more
europepmc   +1 more source

Ileal mucosal bile acid absorption is increased in Cftr knockout mice

, 2019
Matthias Stelzner, Siva G. Somasundaram, Sum P. Lee, Rahul Kuver   +3 more
openalex   +1 more source

CLICK: one-step generation of conditional knockout mice [PDF]

, 2018
Yoshiki Miyasaka, Yoshihiro Uno, Kazuto Yoshimi, Yayoi Kunihiro, Takuji Yoshimura, Tomohiro Tanaka, Harumi Ishikubo, Yuichi Hiraoka, Norihiko Takemoto, Takao Tanaka, Yoshihiro Ooguchi, Paul Skehel, Tomomi Aida, Junji Takeda, Tomoji Mashimo   +14 more
openalex   +1 more source

Enzyme‐Regulated Extended Swelling of Hydrogels for Dehiscence‐Less Tissue Expansions

Advanced Functional Materials, EarlyView.
An interpenetrating hydrogel network with swelling under regulation by enzymatic degradation (INSURED) is fabricated to avoid dehiscence. INSURED remains structurally intact post‐implantation, while HYAL injection enables control over the onset and rate of swelling.
Byung Ik Park, Dong‐yup Lee, Sungsoo Lim, JangHyuk Kim, Min‐Gyu Lee, Chang Seo Park, Hyeonuk Na, Yong Eun Cho, Yun Hyeok Lee, Junsang Doh, Jeong‐Yun Sun   +10 more
wiley   +1 more source

p2rx3 Knockout Mice Have Altered Energy Metabolism in Hippocampal Neurons. [PDF]

Acta Naturae
Zelentsova AS, Pokrovskii MV, Patrakhanov EA, Shmigerova VS, Skorkina MY, Deykin AV.   +5 more
europepmc   +1 more source

Host‐Directed Biomaterials for Combatting Bloodstream Infections: From Macrocyclic Peptides to Immune‐Activating Cell Backpacks

Advanced Functional Materials, EarlyView.
Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou, Jagadish Krishnappa, Justin B. Schaal, Prasad Tongaonkar, Dat Q. Tran, Wenchao Gu, Yung‐Fu Chang, Michael E. Selsted, Shaoyi Jiang, Samir Mitragotri, Michael Super, Christopher J. Bettinger   +11 more
wiley   +1 more source