Results 31 to 40 of about 3,640 (219)
Novel Psychoactive Substances 14Recent Progress on Neuropharmacological Mechanisms of Action for Selected Drugs [PDF]
, 2017 A feature of human culture is that we can learn to consume chemical compounds, derived from natural plants or synthetic fabrication, for their psychoactive effects.
Boris B. , Quednow +8 more
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Substance Abuse: Research and Treatment, 2022 Background: Kratom is taken to self-treat pain and symptoms of psychiatric disorders, including substance-use disorders (SUDs) and opioid withdrawal. Before COVID-19, kratom use was increasing in the US, however, there are few published data on whether ...
Jeffrey M Rogers +3 more
doaj +1 more source
Is there a potential of misuse for Magnolia officinalis compounds/metabolites? [PDF]
, 2017 © 2017 John Wiley & Sons, Ltd.Objective: Magnolia bark contains magnolol, metabolized to tetrahydromagnolol and honokiol, with both GABA-ergic/cannabimimetic activities, hence of possible attraction to vulnerable individuals/recreational misusers ...
Alexeev +32 more
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Current and Future Potential Impact of COVID-19 on Kratom (Mitragyna speciosa Korth.) Supply and Use
Frontiers in Psychiatry, 2020 Kratom (Mitragyna speciosa Korth., Rubiaceae) is native to and has traditional use in Southeast Asia. The number of kratom users outside of Southeast Asia has increased significantly in recent decades with use spreading to the Unites States (US) and ...
Darshan Singh +15 more
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Mitragynine/Corynantheidine Pseudoindoxyls As Opioid Analgesics with Mu Agonism and Delta Antagonism, Which Do Not Recruit beta-Arrestin-2. [PDF]
, 2016 Natural products found in Mitragyna speciosa, commonly known as kratom, represent diverse scaffolds (indole, indolenine, and spiro pseudoindoxyl) with opioid activity, providing opportunities to better understand opioid pharmacology.
Borics, Attila +5 more
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International Journal of Risk and Recovery, 2020 Substance Use Disorder is a major concern for public health. Legal substances are often misused to get “high”. Beside the risk of developing subsequent mental health and physical conditions, one of major risk is related to behavioural changes leading to criminal behaviour.
Sebastien S Prat +2 more
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384 Motives for kratom self-medication: contents of public comments solicited by the FDA
Journal of Clinical and Translational Science, 2022 OBJECTIVES/GOALS: The present study sought to investigate kratom use motives among the U.S population with the goal of discovering previously unknown health-related reasons for kratom use by the general public.
Julia Tobacyk, Brian Parks, Lisa Brents
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Investigating the Impact of Kratom (Mitragyna speciosa) Use Upon Male Sexual Health
Research and Reports in Urology, 2023 Nicholas A Deebel,1 Kyle Scarberry,2 Collette A O’Connor,1 Rahul Dutta,1 Ethan Matz,1 Colleen A Hanlon,3 Ryan P Terlecki1 1Department of Urology, Atrium Health Wake Forest Baptist Medical Center, Winston-Salem, NC, USA; 2Department of Urology, University
Deebel NA +6 more
doaj
Kratom (Mitragyna speciosa)-Induced Hepatitis
ACG Case Reports Journal, 2022 ABSTRACT Kratom is a plant with opioid-like properties known to produce stimulant and analgesic effects. Although there are numerous studies on the psychoactive components of kratom, less is known about the toxicity. Specifically, few reports describe kratom-induced hepatotoxicity and demonstrate histological features.
Devin R. Allison +3 more
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Frontiers in PharmacologyBackground“Kratom” refers to an array of bioactive products derived from Mitragyna speciosa, a tree indigenous to Southeast Asia. Most kratom consumers report analgesic and stimulatory effects, and common reasons for use are to address mental and ...
Jeffrey M. Rogers +5 more
doaj +1 more source