Results 21 to 30 of about 3,640 (219)

An evaluation of adverse drug reactions and outcomes attributed to kratom in the US Food and Drug Administration Adverse Event Reporting System from January 2004 through September 2021

Clinical and Translational Science, 2023
Kratom is a widely used Asian botanical that has gained popularity in the United States due to a perception that it can treat pain, anxiety, and opioid withdrawal symptoms. The American Kratom Association estimates 10–16 million people use kratom. Kratom‐
Xiaotong Li, Patrick Ndungu, Sanya B. Taneja, Maryann R. Chapin, Susan B. Egbert, Krishi Akenapalli, Mary F. Paine, Sandra L. Kane‐Gill, Richard D. Boyce   +8 more
doaj   +1 more source

Kratom availability in California vape shops

Preventive Medicine Reports, 2023
Kratom products are derived from trees native to Southeast Asia and have dose-dependent stimulant and opioid-like effects. Despite being on the Drug Enforcement Administration “Drugs and Chemicals of Concern List,” kratom is legal for sale in most US ...
Molly A. Bowdring, Eric C. Leas, Monika Vishwakarma, Nina C. Schleicher, Judith J. Prochaska, Lisa Henriksen   +5 more
doaj   +1 more source

Lipid profile of regular kratom (Mitragyna speciosa Korth.) users in the community setting.

PLoS ONE, 2020
Background and aimKratom, or Mitragyna speciosa Korth., is a tropical plant that has been reported to exhibit opioid-like effects. Although opioids have been demonstrated to alter the lipid profile of regular users, data on the lipid-altering effects of ...
Mohammad Farris Iman Leong Bin Abdullah, Kok Leng Tan, Salbiah Mohd Isa, Nur Sabrina Yusoff, Nelson Jeng Yeou Chear, Darshan Singh   +5 more
doaj   +1 more source

Association between kratom (Mitragyna speciosa) use and metabolic syndrome

Heliyon, 2022
Background and aims: There are evidence about effects of kratom (Mitragyna speciosa) use on parameters related to metabolic syndrome (MetS). The present study aimed to determine the association between kratom use and MetS.
Aroon La-up, Paleeratana Wongrith, Wiraphon Chaichan, Apinun Aramrattana, Udomsak Saengow   +4 more
doaj   +1 more source

Herbal highs: review on psychoactive effects and neuropharmacology [PDF]

, 2017
Background: A new trend among users of new psychoactive substances’ the consumption of “herbal highs”: plant parts containing psychoactive substances.
Graziano, S, Orsolini, L, Pichini, S., Rotolo, Mc, Schifano, F, Tittarelli, R   +5 more
core   +1 more source

Public Health Implications and Possible Sources of Lead (Pb) as a Contaminant of Poorly Regulated Kratom Products in the United States

Toxics, 2022
Kratom (Mitragyna speciosa) is a tropical tree that is indigenous to Southeast Asia. Kratom leaf products have been used in traditional folk medicine for their unique combination of stimulant and opioid-like effects.
Walter Prozialeck, Alexandra Fowler, Joshua Edwards   +2 more
doaj   +1 more source

7‑hydroxymitragynine is an active metabolite of mitragynine and a key mediator of its analgesic effects [PDF]

, 2019
Mitragynina speciosa, more commonly known as kratom, is a plant native to Southeast Asia, the leaves of which have been used traditionally as a stimulant, analgesic, and treatment for opioid addiction.
Ansonoff, Michael, Gassaway, Madalee M., Grinnell, Steven G., Javitch, Jonathan A., Kruegel, Andrew C., Langreck, Cory, Le Rouzic, Valerie, Majumdar, Susruta, Pasternak, Gavril W., Pekarskaya, Elizabeth A., Pintar, John E., Sames, Dalibor, Uprety, Rajendra   +12 more
core   +3 more sources

Exploring of cardiac autonomic activity with heart rate variability in long-term kratom (Mitragyna speciosa Korth.) users: a preliminary study [PDF]

PeerJ, 2022
Background Kratom is a psychoactive plant used to enhance productivity among laborers in Southeast Asian countries. Previous findings from in vitro research of mitragynine, a major component of kratom, suggested a possible risk of heart function ...
Wanumaidah Saengmolee, Dania Cheaha, Nusaib Sa-ih, Ekkasit Kumarnsit   +3 more
doaj   +2 more sources

The Harm in Kratom [PDF]

The Oncologist, 2017
A case of severe hepatic toxicity associated with the use of kratom, a plant derivative increasingly used as a psychostimulant, is discussed.
Drago, Joshua Z., Lane, Bennett, Kochav, Jonathan, Chabner, Bruce   +3 more
openaire   +2 more sources

Kratom Use in the US: Both a Regional Phenomenon and a White Middle-Class Phenomenon? Evidence From NSDUH 2019 and an Online Convenience Sample

Frontiers in Pharmacology, 2021
Kratom products available in the United States are becoming increasingly diverse both in terms of content and in terms of how they are marketed.
Jeffrey M. Rogers, Kirsten E. Smith, Justin C. Strickland, David H. Epstein   +3 more
doaj   +1 more source