Results 61 to 70 of about 4,369 (260)

Measuring Treatment Effectiveness in Real‐World Substance Use Care: A Community‐Based Program Evaluation

Journal of Addictions &Offender Counseling, Volume 47, Issue 2, Page 195-204, October 2026.
ABSTRACT This study reports findings from a community‐based program evaluation examining treatment effectiveness in a real‐world outpatient substance use care setting. Using a within‐program pre–post design, changes in alcohol and drug use were assessed among clients receiving intensive outpatient services.
Jessie A. Brown, Taryn M. Akgul, Todd F. Lewis, Patti Senn   +3 more
wiley   +1 more source

Human Mitragynine and 7-Hydroxymitragynine Pharmacokinetics after Single and Multiple Daily Doses of Oral Encapsulated Dried Kratom Leaf Powder

Molecules
Kratom leaves, consumed by millions worldwide as tea or ground leaf powder, contain multiple alkaloids, with mitragynine being the most abundant and responsible for most effects.
M. Huestis, M. Brett, John Bothmer, Ramsey Atallah   +3 more
semanticscholar   +1 more source

Novel Histopathologic Features of Diffuse Blue‐Gray Hyperpigmentation Associated With Kratom Use: A Case Report and Literature Review

Journal of Cutaneous Pathology, Volume 53, Issue 10, Page 887-892, October 2026.
ABSTRACT Background Drug‐induced hyperpigmentation accounts for 10%–20% of acquired pigmentary disorders and can be misdiagnosed for other causes such as melasma, post inflammatory changes, or heavy metal deposition. Kratom (Mitragyna speciosa), a Southeast Asian plant with an opioid‐like profile, has been increasingly used in the United States for ...
Rita Kamoua, Kristen Paradine, Craig A. Rohan, Mary McDaniel, Diane Perkins   +4 more
wiley   +1 more source

Kratom use disorder as a gateway to an opioid use disorder

European Psychiatry, 2023
Introduction Kratom (Mitragyna speciosa) is a psychoactive substance native to Thailand and Southeast Asia with stimulant-like effects at lower doses and opioid-like effects at higher doses.
A. C. Borges, D. Machado
doaj   +1 more source

Ecological Momentary Assessment of Self-Reported Kratom Use, Effects, and Motivations Among US Adults

JAMA Network Open
Key Points Question When people use kratom regularly, how and why do they do so and with what effects? Findings Among the 357 kratom consumers surveyed using ecological momentary assessment in this cross-sectional study, most reported using kratom daily ...
Kirsten E. Smith, Leigh V. Panlilio, J. Feldman, O. Grundmann, Kelly E. Dunn, Christopher R. McCurdy, A. Garcia-Romeu, David H. Epstein   +7 more
semanticscholar   +1 more source

Potensi Farmakologi Tanaman Kratom (Mitragyna speciosa Korth.): Review [PDF]

Indonesia sebagai negara tropis memiliki keragaman hayati yang melimpah, termasuk tanaman kratom (Mitragyna speciosa Korth.) yang dikenal memiliki aktivitas farmakologis potensial.
Purwaniati, Purwaniati, Suryanti, Wulan Maulani, Sutrisno, Entris   +2 more
core   +1 more source

Kratom addiction per DSM-5 SUD criteria, and kratom physical dependence: Insights from dosing amount versus frequency

Drug and Alcohol Dependence
Background: Kratom products are widely used in the United States, with inadequate understanding of how dosing amounts/frequencies relate to outcomes.
Jeffrey M. Rogers, S. Weiss, David H. Epstein, O. Grundmann, Katherine Hill, Kirsten E. Smith   +5 more
semanticscholar   +1 more source

Extended‐release buprenorphine in adults with opioid use disorder involving poppy seed tea: An 18‐month retrospective case series

The American Journal on Addictions, Volume 35, Issue 5, Page 638-642, September 2026.
Abstract Background and Objectives Poppy seed tea (PST) contains unpredictable opioid concentrations, destabilising tolerance and increasing overdose risk. Extended‐release buprenorphine (BUP‐XR) provides sustained coverage without daily dosing. Methods Eighteen‐month follow‐up of adults (N = 3) with opioid use disorder (OUD) involving PST in Australia.
John McMaster, Saumiya Seshakumaran, Hesitha Abeysundera, Isha Tipirneni, Rita Hormiz   +4 more
wiley   +1 more source

Kratom: A Narrative Review of the Possible Clinical Uses and Dangers of This Opioid-Like Plant [PDF]

The term kratom refers to a plant species formally known as Mitragyna speciosa. Kratom is composed of over 40 alkaloids, a type of organic compound that contains nitrogen.
Cornett, Elyse M, Mahoney, Taylor C, Edinoff, Amber N, Gong, Jay, Murnane, Kevin S, Varrassi, Giustino, Kaufman, Sarah E, Upshaw, William C, Kaye, Adam M, Kaye, Alan D, Shekoohi, Sahar   +10 more
core   +1 more source

Successful Management of Kratom Use Disorder With Buprenorphine and Naloxone.

, 2023
Kratom is an unregulated herbal supplement that is growing in popularity in the United States. Its primary active ingredients, mitragynine, and 7-hydroxymitragynine, are partial agonists that act on mu- and delta-opioid receptors in the central nervous ...
Mobley, Julian, Hamad, Hamad, Remick, Paul, Arhin, Martin   +3 more
core   +1 more source