Evaluating kratom alkaloids using PHASE
Kratom is a botanical substance that is marketed and promoted in the US for pharmaceutical opioid indications despite having no US Food and Drug Administration approved uses. Kratom contains over forty alkaloids including two partial agonists at the mu opioid receptor, mitragynine and 7-hydroxymitragynine, that have been subjected to the FDA's ...
Christopher R. Ellis +9 more
openaire +4 more sources
Medication experiences in the treatment of opioid use disorders: Insights from Reddit
Abstract Background and Aims Better understanding the challenges faced by patients on medications for opioid use disorder (MOUD), including methadone and buprenorphine, is critical to increasing their use/retention. Social media platforms such as Reddit offer a space for patients to share their experiences with medications.
Alexandra Almeida +5 more
wiley +1 more source
Uji Efek Sedatif Fraksi Etanol Daun Kratom (Mitragyna Speciosa Korth.) Pada Mencit Jantan Galur Balb/c [PDF]
Kratom (Mitragyna speciosa Korth.) is one of traditional medical plant that canproduces both stimulant effects (in low doses) and sedative effects (in high doses).
Ridayani, Y. (Yeni)
core +1 more source
Novel psychoactive substances of interest for psychiatry [PDF]
Novel psychoactive substances include synthetic cannabinoids, cathinone derivatives, psychedelic phenethylamines, novel stimulants, synthetic opioids, tryptamine derivatives, phencyclidine-like dissociatives, piperazines, GABA-A/B receptor agonists, a ...
Corkery, John +3 more
core +1 more source
Studies on the phase I and II metabolism and the toxicological analysis of the alkaloids of the herbal drug of abuse Mitragyna speciosa Korth. (Kratom) using gas chromatography-mass spectrometry and liquid chromatography coupled to low- and high-resolution linear ion trap mass spectrometry [PDF]
In the presented studies, the herbal drug Kratom (Mitragyna speciosa) was investigated regarding its metabolism and its toxicological analysis in rat and human urine.
Philipp, Anika-Anina
core
Abstract Introduction National surveillance data in Malaysia has observed a marked reduction in the number of new HIV cases among people who inject drugs (PWID) in the past decade. This study sought to estimate the current prevalence and associated risk factors of HIV and hepatitis C virus (HCV) among PWID in suburban areas of Klang Valley, Malaysia ...
Joselyn Pang +5 more
wiley +1 more source
Uji Efek Sedatif Ekstrak N-heksan Dari Daun Kratom (Mitragyna Speciosa Korth.) Pada Mencit Jantan Galur Balb/c [PDF]
Insomnia is a sleep disorder that can cause a variety of serious health problemsrequiring treatment. The using of synthetic drugs have dangerous side effects than therapywhich is resulted. Therefore, alternative treatments which derived from natural such
Hidayati, A. (Anna)
core +1 more source
An adolescent with an altered state of mind [PDF]
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Moressa, Valentina +3 more
core +1 more source
Abstract Background U.S. construction workers experience high rates of injury that can lead to chronic pain. This pilot study examined nonpharmacological (without medication prescribed by healthcare provider) and pharmacological (e.g., prescription opioids) pain management approaches used by construction workers.
Aurora B. Le +5 more
wiley +1 more source
Kratom (Mitragyna speciosa): ¿droga emergente o bala mágica? [PDF]
En los últimos años, un número indeterminado y creciente de sustancias con actividad psicotrópica están siendo introducidas en contextos recreativos a través del mercado tecnológico que suponen internet y las nuevas tecnologías, tratando de franquear ...
Giner García, Ricardo +1 more
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