Results 101 to 110 of about 3,153,249 (347)

CD168 Identifies Proliferating Pancreatic Islet Cells in Murine and Human

Advanced Science, EarlyView.
This study identifies CD168 as a conserved surface marker for proliferating β‐cells in mouse, human islets, and pancreatic islet tumors. CD168⁺ cells show high proliferation and low insulin expression. CD168+ cells form mostly uni‐β lineage clones, and some of the clones are multi‐lineage.
Shubo Yuan, Jiafu Li, Min Shao, Haili Bao, Ajun Geng, Jialin Yang, Yu Tao, Xinyi Chen, Tianxiong Xiao, Chunye Liu, Zhiyao Xie, Wenqian Song, Qing Cissy Yu, Hongxing Fu, Xu Han, Taochen He, Wenquan Wang, Jianfeng Chen, Sheng Yan, Shaohua Song, Liang Liu, Yi Arial Zeng   +21 more
wiley   +1 more source

Targeting Itga8 Mitigates Neurogenic Bladder Fibrosis Driven by Trem2⁺ Macrophage‐Derived Fn1 via FAK/RhoA/ROCK Signaling

Advanced Science, EarlyView.
Normal bladders exhibit quiescent fibroblasts/macrophages, whereas neurogenic bladders show acute‐phase Itga8⁺ fibroblast expansion driven by Trem2⁺ macrophage‐secreted Fn1, which activates FAK/RhoA/ROCK signaling, promotes cytoskeletal remodeling, and upregulates pro‐fibrotic genes.
Jiaxin Wang, Siyuan Wang, Lida Ren, Xinqi Liu, Lei Zhang, Peng Hu, Wenchao Xu, Shuaixiang Zheng, Jihong Liu, Qing Ling   +9 more
wiley   +1 more source

Structure and function of the divalent anion/Na+ symporter from Vibrio cholerae and a humanized variant

Nature Communications, 2017
Divalent anion/Na+ symporter (DASS) transporters move intermediates of the Krebs cycle across the cell membrane. Here the authors present the substrate-bound structures of VcINDY, a DASS from Vibrio cholerae, which provide insights into the underlying ...
Rongxin Nie, Steven Stark, Jindrich Symersky, Ronald S. Kaplan, Min Lu   +4 more
doaj   +1 more source

Towards understanding the variability in biospheric CO2 fluxes:Using FTIR spectrometry and a chemical transport model to investigate the sources and sinks of carbonyl sulfide and its link to CO2 [PDF]

, 2016
Understanding carbon dioxide (CO2) biospheric processes is of great importance because the terrestrial exchange drives the seasonal and interannual variability of CO2 in the atmosphere. Atmospheric inversions based on CO2 concentration measurements alone
A. Wolf, B. Lejeune, E. Mahieu, I. Baker, J. Berry, J. E. Campbell, J. Hannigan, J. Mendonca, J. Notholt, K. Strong, M. Palm, N. Jones, N. M. Deutscher, N. M. Deutscher, P. Suntharalingam, S. Conway, S. Kremser, T. Warneke, Y. Wang   +18 more
core   +4 more sources

Wirelessly Powered Soft Magnetic Robot with Microneedle for Electrical Stimulation and Drug Delivery

Advanced Intelligent Systems, EarlyView.
A wirelessly powered soft magnetic robot integrates microneedles to enable dual functions: electrical stimulation (86.7% efficiency at 6 cm, tunable 0–20 V voltage, 0.4–50 ms pulses) and drug delivery. It switches surfaces via magnetic fields for gastrointestinal tract locomotion and treatment, with in vitro validation in fresh pig gut showing ...
Song Zhao, Liwen Zhang, Shengbin Zhang, Botao Ma, Meng Wang, Yipan Zuo, Xinzhao Zhou, Xueshan Jing, Huawei Chen   +8 more
wiley   +1 more source

Metabolomic Profiling Reveals PGPR-Driven Drought Tolerance in Contrasting Brassica juncea Genotypes

Metabolites
Background: Drought stress is a major abiotic factor limiting Brassica juncea productivity, resulting in significant yield reductions. Plant Growth-Promoting Rhizobacteria (PGPR) have shown potential in enhancing drought tolerance; however, the ...
Asha Rani Sheoran, Nita Lakra, Baljeet Singh Saharan, Annu Luhach, Yogesh K. Ahlawat, Rosa Porcel, Jose M. Mulet, Prabhakar Singh   +7 more
doaj   +1 more source

Bipolar polaron pair recombination in P3HT/PCBM solar cells [PDF]

, 2015
The unique properties of organic semiconductors make them versatile base materials for many applications ranging from light emitting diodes to transistors.
Behringer, Konstantin M., Brandt, Martin S., Corazza, Michael, Galfe, Natalie E., Gevorgyan, Suren A., Krebs, Frederik C, Kupijai, Alexander J., Schaeble, Florian G., Stutzmann, Martin   +8 more
core   +4 more sources

Mimicking Life: Autonomous Oscillating Artificial Cilia Driven by Chemical Power

Advanced Intelligent Systems, EarlyView.
The synthesis and motion analysis of chemically actuated, individually autonomous artificial cilia are presented. Driven by an internal chemical reaction, the self‐driven individual cilia require no external stimuli. They undergo periodic oscillatory motion with a 3D beat pattern and exhibit chemotactic shifts, reminiscent of biological systems.
Rajata Suvra Chakrovorty, Yaqeen Salatneh Ashqer, Suzanne Ahmed   +2 more
wiley   +1 more source

Time‐ and dose‐related pathological changes in knee osteoarthritis rat model induced by monosodium iodoacetate

Animal Models and Experimental Medicine, EarlyView.
Time‐ and dose‐related pathological changes of knee osteoarthritis rat model induced by monosodium iodoacetate. Abstract Knee osteoarthritis (KOA) is a chronic degenerative disease. Monosodium iodoacetate (MIA) induction is the most commonly used therapeutic effect evaluation and mechanism of action research model; we observed a lack of standardization
Wei Pu, Qi Liu, Shuyan Xue, Siyuan Li, Nan Nan, Yang Liu, Huiqin Hao   +6 more
wiley   +1 more source

Myocardial infarct-sparing effect of ischemic preconditioning abrogated in cirrhotic rat through involvement of mitochondrial permeability transition pore [PDF]

, 2012
Despite all studies undertaken mechanism of cirrhotic cardiomyopathy the role of cirrhosis on ischemia-reperfusion (I/R) injury and ischemic preconditioning (IPC) phenomenon hasn't been explored yet.
Dehpour, A.R., Jafrazedeh, F., Khori, V., Mohimani, H.R., Mohsen, N.   +4 more
core