Mitochondrial Probe Methyltriphenylphosphonium (TPMP) Inhibits the Krebs Cycle Enzyme 2-Oxoglutarate Dehydrogenase. [PDF]
PLoS ONE, 2016 Methyltriphenylphosphonium (TPMP) salts have been widely used to measure the mitochondrial membrane potential and the triphenylphosphonium (TPP+) moiety has been attached to many bioactive compounds including antioxidants to target them into mitochondria
Moustafa Elkalaf +4 more
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GPR91: expanding the frontiers of Krebs cycle intermediates. [PDF]
Cell Commun Signal, 2016 Since it was discovered, the citric acid cycle has been known to be central to cell metabolism and energy homeostasis. Mainly found in the mitochondrial matrix, some of the intermediates of the Krebs cycle are also present in the blood stream. Currently, there are several reports that indicate functional roles for Krebs intermediates out of its cycle ...
de Castro Fonseca M +4 more
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Metabolites, 2021 Very long-chain acyl-CoA dehydrogenase deficiency (VLCADD, OMIM 609575) is associated with energy deficiency and mitochondrial dysfunction and may lead to rhabdomyolysis and cardiomyopathy.
Igor Radzikh +5 more
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Instability and invariant measure in the mathematical model for oxidative phosphorylation and ATP synthesis in the cell [PDF]
The Ukrainian Biochemical Journal, 2023 The aim of this work was to analyze the process of oxidative phosphorylation and ATP synthesis in a cell using a mathematical model. The scenario of occurrence of the autoperiodic and chaotic modes depending on the ATP dissipation values was determined ...
V. I. Grytsay
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The Impact of Krebs Cycle Intermediates on the Endocrine System and Immune System: A Comparison
Endocrines, 2023 Introduction: The Krebs cycle is an important set of reactions that synthesize different molecules and substances that affect various organs. The objective of this paper was to compare the effects of Krebs cycle intermediates on the endocrine system and ...
Borros M. Arneth
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Succinate and succinate dehydrogenase as a «foothold» in the Krebs cycle in critical conditions
Антибиотики и Химиотерапия, 2023 Purpose. Search and presentation of data from experimental and clinical studies reflecting the central role of succinate and succinate dehydrogenase in the regulation of adaptation mechanisms in critical conditions. Material and methods.
Yu. P. Orlov +9 more
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Nobel prize winners in metabolism history and diabetology
Сахарный диабет, 2023 The 20th century was the time of large-scale discoveries and their widespread recognition. Metabolism studies and their role in living organisms deserve special attention.
Y. A. El-Taravi +4 more
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The Nobel laureates’ contributions to the study of carbohydrate metabolism and its regulation. A. Harden, H. Euler-Chelpin, C. F. Cori, G. T. Cori, E. Sutherland, L. F. Leloir, H. Krebs, F. Lipmann, P. Mitchell [PDF]
The Ukrainian Biochemical Journal, 2020 Carbohydrate metabolism is a complex and multi-stage process. Many scientists (biochemists, physiologists, chemists) worked on deciphering this process, but only some of them were awarded the Nobel Prize.
R. P. Vynogradova +2 more
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Tricarboxylic Acid (TCA) Cycle Intermediates: Regulators of Immune Responses
Life, 2021 The tricarboxylic acid cycle (TCA) is a series of chemical reactions used in aerobic organisms to generate energy via the oxidation of acetylcoenzyme A (CoA) derived from carbohydrates, fatty acids and proteins.
Inseok Choi, Hyewon Son, Jea-Hyun Baek
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Enzyme expression in indica and japonica rice cultivars under saline stress=Expressão de enzimas em cultivares de arroz indica e japonica sob estresse salino [PDF]
Acta Scientiarum: Biological Sciences, 2012 The southern State of Rio Grande do Sul (RS) is the main rice producer in Brazil with a 60% participation of the national production and 86% participation of the region. Rice culture irrigation system is done by flooding, which leads to soil salinization,
Cristina Rodrigues Mendes +5 more
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