Krebs-cycle-deficient hereditary cancer syndromes are defined by defects in homologous-recombination DNA repair. [PDF]
Nat Genet, 2018 The hereditary cancer syndromes hereditary leiomyomatosis and renal cell cancer (HLRCC) and succinate dehydrogenase–related hereditary paraganglioma and pheochromocytoma (SDH PGL/PCC) are linked to germline loss-of-function mutations in genes encoding ...
Sulkowski PL +14 more
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Instability and invariant measure in the mathematical model for oxidative phosphorylation and ATP synthesis in the cell [PDF]
The Ukrainian Biochemical Journal, 2023 The aim of this work was to analyze the process of oxidative phosphorylation and ATP synthesis in a cell using a mathematical model. The scenario of occurrence of the autoperiodic and chaotic modes depending on the ATP dissipation values was determined ...
V. I. Grytsay
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Fermentation, 2023 This article describes the effect of organic acids and ultrasound on the physiological and biochemical properties of yeast, which was used to obtain biologically active peptides. The research featured brewer’s yeast S. cerevisiae W-34/70 cultivated in 11%
L. Permyakova +7 more
semanticscholar +1 more source
Nobel prize winners in metabolism history and diabetology
Сахарный диабет, 2023 The 20th century was the time of large-scale discoveries and their widespread recognition. Metabolism studies and their role in living organisms deserve special attention.
Y. A. El-Taravi +4 more
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Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle
Nature, 2019 Koen H. G. Verschueren +10 more
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Sulfate radicals enable a non-enzymatic Krebs cycle precursor. [PDF]
Nat Ecol Evol, 2017 The evolutionary origins of the Krebs cycle (tricarboxylic acid cycle) are not currently clear. Despite the existence of a simple non-enzymatic Krebs cycle catalyst being dismissed only a few years ago as ‘an appeal to magic’, citrate and other ...
Keller MA +3 more
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Tricarboxylic Acid (TCA) Cycle Intermediates: Regulators of Immune Responses
Life, 2021 The tricarboxylic acid cycle (TCA) is a series of chemical reactions used in aerobic organisms to generate energy via the oxidation of acetylcoenzyme A (CoA) derived from carbohydrates, fatty acids and proteins.
Inseok Choi, Hyewon Son, Jea-Hyun Baek
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Enzyme expression in indica and japonica rice cultivars under saline stress=Expressão de enzimas em cultivares de arroz indica e japonica sob estresse salino [PDF]
Acta Scientiarum: Biological Sciences, 2012 The southern State of Rio Grande do Sul (RS) is the main rice producer in Brazil with a 60% participation of the national production and 86% participation of the region. Rice culture irrigation system is done by flooding, which leads to soil salinization,
Cristina Rodrigues Mendes +5 more
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The Nobel laureates’ contributions to the study of carbohydrate metabolism and its regulation. A. Harden, H. Euler-Chelpin, C. F. Cori, G. T. Cori, E. Sutherland, L. F. Leloir, H. Krebs, F. Lipmann, P. Mitchell [PDF]
The Ukrainian Biochemical Journal, 2020 Carbohydrate metabolism is a complex and multi-stage process. Many scientists (biochemists, physiologists, chemists) worked on deciphering this process, but only some of them were awarded the Nobel Prize.
R. P. Vynogradova +2 more
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Fragmentation of Dicarboxylic and Tricarboxylic Acids in the Krebs Cycle Using GC-EI-MS and GC-EI-MS/MS. [PDF]
Mass Spectrom (Tokyo), 2019 Isotope labeling measurements using mass spectrometry can provide informative insights on the metabolic systems of various organisms. The detailed identification of carbon positions included in the fragment ions of dicarboxylic and tricarboxylic acids in
Okahashi N +4 more
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