Results 41 to 50 of about 2,520,144 (213)
Kynurenic acid and cancer: facts and controversies [PDF]
Cellular and Molecular Life Sciences, 2019 Abstract Kynurenic acid (KYNA) is an endogenous tryptophan metabolite exerting neuroprotective and anticonvulsant properties in the brain. However, its importance on the periphery is still not fully elucidated. KYNA is produced endogenously in various types of peripheral cells, tissues and by gastrointestinal microbiota.
Katarzyna Walczak +3 more
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Kynurenic Acid and Acupuncture on Chronic Pain [PDF]
, 2023 Introduction: Approximately 20% of the population experiences chronic pain. Chronic pain is characterized as a persistent sensation of discomfort that lasts for a duration exceeding three months subsequent to the experience of a traumatic incident or ...
Karina Pratiwi, Nancy Margarita Rehatta, Ario Imandiri, Wiwiek Indriyani Maskoep, Pungky Mulawardhana
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Cells, 2022 Glutamate-receptor-mediated hyperexcitability contributes to seizure generation in temporal lobe epilepsy (TLE). Tryptophan–kynurenine pathway (TKP) metabolites regulate glutamate receptor activity under physiological conditions.
Soumil Dey +5 more
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Vagus Nerve Stimulation in Refractory Epilepsy: Effects on Pro- and Anti-Inflammatory Cytokines in Peripheral Blood [PDF]
, 2010 Objective: The vagus nerve has important immunological functions that may be relevant for its anticonvulsive action. We postulate that this anticonvulsive action is activated by a shift in the immune system resulting in a reduction of neurotoxic and an ...
J.S.H. Vles +15 more
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Naphthalene-functionalized resorcinarene as selective, fluorescent self-quenching sensor for kynurenic acid† [PDF]
, 2022 Kynurenic acid is a by-product of tryptophan metabolism in humans, with abnormal levels indicative of disease. There is a need for water-soluble receptors that selectively bind kynurenic acid, allowing for detection and quantification. We report here the
Karle, Anna +8 more
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European Psychiatry, 2021 Introduction The tryptophan pathway along with its two branches of metabolism to serotonin and kynurenine seems to be affected in major depression.
R. Colle +4 more
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Metabolites, 2017 The aim of this pilot study is to evaluate sarcosine, uracil, and kynurenic acid in urine as potential biomarkers in prostate cancer detection and progression monitoring. Sarcosine, uracil, and kynurenic acid were measured in urine samples of 32 prostate
Georgios Gkotsos +6 more
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Chestnut honey - a source of kynurenic acid
U ovom radu je opisan med od kestena, njegov kemijski sastav i svojstva. Med od kestena se posebno ističe visokim sadržajem kinurenske kiseline u usporedbi s ostalim izvorima poput, ribe, rajčica i drugih prehrambenih proizvoda.
Strunje, Josip
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BMC Psychiatry, 2023 Previous studies reported significantly altered tryptophan catabolite concentrations in major depression. Thus, tryptophan catabolites were considered as potential biomarkers of depression and their modulators as potential targets for ...
Matthias Michal +13 more
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Distress Intolerance, Kynurenic Acid, and Schizophrenia [PDF]
JAMA Psychiatry, 2014 We are all intuitively aware that when we are under stress, we think differently and often less well than when we are calmer. The study by Chiapelli et al1 in this issue of the journal addresses some of the critical links underlying the effects of stress on cognition.
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