Results 171 to 180 of about 2,991,386 (293)

Immune Evasion of Helicobacter pylori and Extra‐Gastric Cancer Risk

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Helicobacter pylori (H. pylori) is a group 1 gastric carcinogen that plays a significant role in extra‐gastric digestive system cancers. H. pylori disrupts host cell homeostasis through expression of virulence factors leading to immune evasion as well as persistent gastric mucosal colonization. H. pylori infection has been shown to play a role
Evren Doruk Engin, Ayse Basak Engin, Atilla Engin   +2 more
wiley   +1 more source

Uncovering the Link Between Kynurenic Acid Pathway and Kidney Failure

Kidney International Reports
Introduction: Recent studies have focused on some uremic toxins, particularly those derived from tryptophan, as potential modifiable risk factors of chronic kidney disease (CKD) progression.
Carolla El Chamieh, Sophie Liabeuf, Islam Amine Larabi, Natalia Alencar De Pinho, Margaux Costes-Albrespic, Luc Frimat, Céline Lange, Yves-Édouard Herpe, Jean-Charles Martin, Pierre Letourneau, Benoit Bérengère, Christophe Soulage, Stéphane Burtey, Jean-Claude Alvarez, Laetitia Koppe, Ziad A. Massy, Prs T. Hannedouche, B. Moulin, Dr A. Klein, Pr C. Combe, Dr J.P. Bourdenx, Dr A. Keller, Dr C. Delclaux, Dr B. Vendrely, Dr B. Deroure, Dr A. Lacraz, Dr T. Lobbedez, Dr I. Landru, Pr Z. Massy, Pr P. Lang, Dr X. Belenfant, Pr E. Thervet, Dr P. Urena, Dr M. Delahousse, Dr C. Vela, Pr M. Essig, Dr D. Clément, Dr H. Sekhri, Dr M. Smati, Dr M. Jamali, Dr B. Hacq, Dr V. Panescu, Dr M. Bellou, Pr Luc Frimat, Pr N. Kamar, Prs C. Noël et F. Glowacki, Dr N. Maisonneuve, Dr R. Azar, Dr M. Hoffmann, Pr M. Hourmant, Dr A. Testa, Dr D. Besnier, Pr G. Choukroun, Dr G. Lambrey, Pr S. Burtey, Dr G. Lebrun, Dr E. Magnant, Pr M. Laville, Pr D. Fouque, L. Juillard, Dr C. Chazot, Pr P. Zaoui, Dr F. Kuentz   +62 more
doaj   +1 more source

The vesicle trafficking R‐SNARE VAMP714 connects auxin responses, ROS and ion homeostasis in Arabidopsis under salt stress

New Phytologist, EarlyView.
Network of VAMP714‐dependent interactions during salt stress. Summary Plant responses to salt stress include an altered root architecture mediated by ion imbalances, reactive oxygen species (ROS) accumulation, and altered hormonal responses. Auxin is implicated in these processes.
Jialei Sun, Julien Agneessens, Jennifer F. Topping, Keith Lindsey   +3 more
wiley   +1 more source

Does the kynurenine pathway play a pathogenic role in autism spectrum disorder?

Brain, Behavior, & Immunity - Health
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in communication, sociability, and repetitive/stereotyped behavior.
Danielle Santana-Coelho
doaj   +1 more source

LUCID: An Integrative Approach for Target Discovery and dsRNA Design in Plant Fungal Pathogens

Plant Biotechnology Journal, EarlyView.
LUCID: A computational pipeline for RNAi‐based biofungicide design. ABSTRACT Phytopathogenic fungi pose an escalating threat to global food security and ecosystem stability, as resistance and environmental concerns diminish the effectiveness of conventional fungicides.
Lucía Jiménez‐Castro, Alba López‐Laguna, Dolores Férnandez‐Ortuño, Alejandro Pérez‐García, Álvaro Polonio   +4 more
wiley   +1 more source

From Infection to Anxiety: A Sequential Model Linking Latent Toxoplasmosis to Psychological Distress via Health and Stress

Scandinavian Journal of Psychology, EarlyView.
ABSTRACT Identifying the drivers of chronic stress is crucial for understanding its impact on mental health. Latent toxoplasmosis, a widespread parasitic infection, has been linked to various psychological changes. The Stress‐Coping Hypothesis proposes that at least some of these changes are consequences of chronic stress arising from the infection's ...
Jaroslav Flegr, Ashkan Latifi, Šárka Kaňková   +2 more
wiley   +1 more source

[Enzymes of the kynurenine pathway].

Postepy higieny i medycyny doswiadczalnej, 2002
In this review, the role of kynurenine pathway enzymes (tryptophan 2,3-dioxygenase, indoleamine 2,3-dioxygenase, formamidase, kynurenine aminotransferase, kynurenine 3-hydroxylase, kynureninase, 3-hydroxyanthranilic acid oxygenase, picolinic carboxylase, quinolinic acid phosphoribosyltransferase) in the synthesis of tryptophan products degradation was ...
A, Tankiewicz, D, Pawlak, W, Buczko
openaire   +1 more source

Intramuscular pathways of maladaptation in overtraining syndrome

The Journal of Physiology, EarlyView.
Abstract figure legend The transition from adaptive overreaching to maladaptive overtraining and mechanisms through which excessive training load can lead to performance decline. Four interconnected pathophysiological domains are highlighted: neural fatigue, involving both central and peripheral components such as altered sensory feedback and reflex ...
Emily Shorter, Oscar Horwath, Sabrina Tzivia Barsky, Ferdinand von Walden, Johanna T. Lanner   +4 more
wiley   +1 more source

Changes in kynurenine metabolites in the gray and white matter of the dorsolateral prefrontal cortex of individuals affected by schizophrenia

Schizophrenia
Alterations in the kynurenine pathway of tryptophan metabolism have been implicated in the pathophysiology of schizophrenia. Here, we performed an in-depth analysis of all metabolites of the kynurenine pathway, i.e., tryptophan (TRY), kynurenic acid ...
Nico Antenucci, Giovanna D’Errico, Francesco Fazio, Ferdinando Nicoletti, Valeria Bruno, Giuseppe Battaglia   +5 more
doaj   +1 more source

The mediating role of the kynurenine pathway in longitudinal associations between dietary intake and quality of life in colorectal cancer survivors up to 12 months posttreatment

International Journal of Cancer, Volume 159, Issue 1, Page 122-143, 1 July 2026.
What's New? Many colorectal cancer survivors experience reduced health‐related quality of life (HRQoL), often lasting years after diagnosis. Healthy dietary patterns and even individual macro‐ and micronutrients, however, can potentially improve HRQoL.
Daniëlle D. B. Holthuijsen, Judith J. M. Rijnhart, Eline H. van Roekel, Martijn J. L. Bours, Per M. Ueland, Stéphanie O. Breukink, Maryska L. G. Janssen‐Heijnen, Joop L. Konsten, Eric T. P. Keulen, Adrian McCann, Stefanie Brezina, Biljana Gigic, Jennifer Ose, Matty P. Weijenberg, Simone J. P. M. Eussen   +14 more
wiley   +1 more source