The kynurenine pathway in depression and schizophrenia: convergent signals, divergent states, and clinical signatures. [PDF]
EXCLI JTanaka M, Vécsei L.
europepmc +1 more source
Second‐trimester multimetabolite panel for early preeclampsia rule‐out
International Journal of Gynecology &Obstetrics, Volume 174, Issue 3, Page 1644-1654, September 2026.Abstract Objective We aimed to establish a high‐sensitivity, multimetabolite rule‐out model for the development of preeclampsia (PE), prioritizing minimizing false negatives to exclude low‐risk individuals from intensive surveillance confidently. Methods In this prospective, nested case–control study, maternal serum samples were collected between 20+0 ...
Matthews Silva Martins +7 more
wiley +1 more source
Repetitive tooth-clenching triggers kynurenine pathway activation in masseter muscle of women with temporomandibular disorders myalgia. [PDF]
Pain RepBarjandi G +5 more
europepmc +1 more source
Targeting the intratumoral microbiota to overcome cancer immunotherapy resistance
Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.This review delineates the mechanisms of intratumoral microbiota in cancer immunotherapy resistance, and offers strategies for microbiota‐targeted precision immunotherapy. Abstract Cancer remains a significant global health threat. The tumor microenvironment (TME) is a sophisticated ecological niche that exerts a pivotal effect on treatment outcomes ...
Bufu Tang +14 more
wiley +1 more source
The Role of Downstream Kynurenine Pathway Metabolites in the Modulation of Cardiovascular Disease Development in Chronic Kidney Disease. [PDF]
Int J Tryptophan ResZabłudowska M +3 more
europepmc +1 more source
The Journal of Clinical Pharmacology, Volume 66, Issue 9, September 2026.Abstract Accurate drug concentration measurement is essential for precision pharmacotherapy, but conventional therapeutic drug monitoring (TDM) requires venous sampling, increasing patient burden, and potentially limiting participation in TDM and model‐informed precision dosing (MIPD).
Hari Prabhath Tummala +5 more
wiley +1 more source
Kynurenine pathway dysregulation in attention-deficit hyperactivity disorder: Impact on N-methyl-D-aspartate receptors and phasic dopamine maturation. [PDF]
World J Clin PediatrNagamine T.
europepmc +1 more source
JGH Open, Volume 10, Issue 9, September 2026.ABSTRACT With the consumption of protein consumption increasing globally, there are gaps in our understanding of the differences in protein sources, particularly between animal and plant proteins and their recommendations for patients with Inflammatory Bowel Disease (IBD).
Mustafa Mohamedrashed +4 more
wiley +1 more source
Pharmacological Modulation of the Kynurenine Pathway Using PF-04859989 Modulates PACAP Signaling in Migraine-Relevant Trigeminal Sensitization. [PDF]
BiomoleculesVágvölgyi-Sümegi E +9 more
europepmc +1 more source
Autoimmunity: Molecular Mechanisms, Biomarkers, and Therapeutic Opportunities
MedComm, Volume 7, Issue 9, September 2026.Major types of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming involved in autoimmune diseases. The roles of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming in autoimmune diseases have been a major research focus in recent years.
Jialong Kuang +10 more
wiley +1 more source