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Addiction and the Kynurenine Pathway: A New Dancing Couple?

Pharmacology & Therapeutics, 2021
Drug use poses a serious threat to health systems throughout the world and the number of consumers rises relentlessly every year. The kynurenine pathway, main pathway of tryptophan degradation, has drawn interest in this field due to its relationship ...
Esther O'Shea, Rebeca Vidal, Leticia Gil de Biedma-Elduayen   +2 more
exaly   +2 more sources

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Tryptophan Metabolism in Depression: A Narrative Review With a Focus on Serotonin and Kynurenine Pathways

International Journal of Molecular Sciences, 2022
Nuno Vale, Ana Salome Correia
exaly  

Evidence That a Deviation in the Kynurenine Pathway Aggravates Atherosclerotic Disease in Humans

Journal of Internal Medicine, 2021
Ulf Hedin, Daniel Ketelhuth, Thue W Schwartz   +2 more
exaly  

Dysregulation of Kynurenine Pathway and Potential Dynamic Changes of Kynurenine in Schizophrenia: A Systematic Review and Meta-Analysis

Neuroscience and Biobehavioral Reviews, 2021
Bing Cao, Zihang Pan, Dongfang Wang
exaly  

The Footprint of Kynurenine Pathway in Cardiovascular Diseases

International Journal of Tryptophan Research, 2022
Moein Ala, Seyed Parsa Eftekhar
exaly  

Recent Advances in Clinical Trials Targeting the Kynurenine Pathway

Pharmacology & Therapeutics, 2022
Gilles J. Guillemin, Benjamin Heng, Bruce J Brew   +2 more
exaly  

Kynurenine Pathway Metabolism in Human Astrocytes: A Paradox for Neuronal Protection

Journal of Neurochemistry, 2001
Gilles J. Guillemin, Stephen J. Kerr, Bruce J Brew   +2 more
exaly  

The Role of the Kynurenine Signaling Pathway in Different Chronic Pain Conditions and Potential Use of Therapeutic Agents

International Journal of Molecular Sciences, 2020
Nebojsa Nick Knezevic, Filip Jovanovic, Kenneth D Candido   +2 more
exaly  

Modulators of the Kynurenine Pathway of Tryptophan Metabolism: Synthesis and Preliminary Biological Evaluation of (S)-4-(Ethylsulfonyl)Benzoylalanine, a Potent and Selective Kynurenine Aminotransferase II (KAT II) Inhibitor

ChemMedChem, 2006
Maura Marinozzi, Robert Schwarcz, Gabriele Costantino   +2 more
exaly