Results 191 to 200 of about 1,141,006 (274)

On the correlation of tryptophan and its kynurenine pathway metabolites level in blood, saliva and urine in systemic sclerosis patients. [PDF]

Rheumatol Int
Turska-Kozłowska M, Wielgosz A, Stachniuk A, Fornal E, Parada-Turska J.   +4 more
europepmc   +1 more source

Metabolism in Tumor: Mechanisms and Therapeutic Perspectives

MedComm, Volume 7, Issue 9, September 2026.
Tumor metabolic reprogramming converges on three hubs—the SREBP1/2–FASN–SCD1 lipogenic axis, the HIF‐1α–GLUT1–LDHA glycolytic axis, and the LDLR–SCARB1–LXR cholesterol system—which integrate transcriptional, epigenetic (histone lactylation, m6A), and microenvironmental inputs to generate metabolic plasticity, immune evasion, and therapy resistance ...
Jia‐Chen Cheng, Yi‐Xuan Hu, Xiang‐Chun Huang, Shan Jiang, Jie‐Lin Wang, Yang Zhao, Shuo Chen   +6 more
wiley   +1 more source

Docking Analysis of Drugs Used in the Treatment of Alzheimer's Disease, Using Cell Membrane Receptors and Enzymes of the Kynurenine Pathway: A Pilot Study. [PDF]

Int J Mol Sci
Badawy AAB, Dawood S, Clanchy FIL, Williams RO, Stone TW.   +4 more
europepmc   +1 more source

Amino Acid Metabolism in Health and Disease

MedComm, Volume 7, Issue 9, September 2026.
This graphical abstract delineates the multifaceted role of amino acid metabolism in health and disease. It illustrates how amino acids sustain physiological homeostasis across the liver, kidney, brain, heart, intestine, muscle, skeleton, and immune system.
Zhiwei Su, Jinyu Liu, Xiaoliang Deng, Yanqun Luo, Haiping Xue, Lei Wang, Lianjun Xing, Tao Wu   +7 more
wiley   +1 more source

Integrated biomarkers of oxidative stress NLRP3 inflammasome and kynurenine pathway reflect disease severity and diagnostic discrimination in depression. [PDF]

Sci Rep
AlRasheed HA, El-Hanafy AA, Bahaa MM, Hamza E, Kamel MM, El-Hanafy DA, Eltantawy N, Yasser M, Al-Dhelaan RA, Radwan KH, El-Sayed AA, Eladaroussy MM, Kamaleldein Rizk KA, Ebrahim MHE, Elshorbagi N.   +14 more
europepmc   +1 more source

Metabolic Syndrome: From Mechanisms to Therapeutic Interventions

MedComm, Volume 7, Issue 9, September 2026.
A comprehensive overview of molecular mechanisms delves into the potential disease mechanisms of metabolic syndrome, including complex mechanisms such as insulin resistance, chronic low‐grade inflammation, oxidative stress, and epigenetic modifications, and how these mechanisms contribute to the development of metabolic syndrome. Here, the relationship
Mengyao Yan, Qian Xiang
wiley   +1 more source

Modulation of the Kynurenine Pathway: A New Approach for Treating Neurodegeneration. [PDF]

Life (Basel)
Banaszkiewicz JK, Kukiełka A, Kudyk E, Walczak ŁJ, Wicha-Komsta K, Herbet M, Piątkowska-Chmiel I, Nowicki G, Mielnik CE, Kocki T.   +9 more
europepmc   +1 more source

Neurocardiology: Brain–Heart Interactions in the Heart

MedComm, Volume 7, Issue 9, September 2026.
The heart and brain maintain systemic homeostasis through bidirectional communication involving neural, biochemical, and mechanical pathways. Dysregulation of these pathways contributes to a spectrum of conditions involving heart–brain interactions, including Takotsubo syndrome, the epileptic heart, stroke–heart syndrome, heart failure, cardiac ...
Wentao Wang, Hao Jia, Han Han, Jiangping Song   +3 more
wiley   +1 more source

Targeting the AHR-IDO1-kynurenine pathway in TREM2⁺ macrophages restores antitumor immunity in thyroid cancer. [PDF]

Front Immunol
Le F, Huang X, Jiang Y, Lv S, Chen Y.
europepmc   +1 more source

Handbook for safe and ethical peer mentoring with women surviving domestic abuse

A handbook and associated policy documents for Pathway Project, Lichfield, Staffordshire. including process, confidentiality statement and processes to be followed when acting as a volunteer peer mentoring with women surviving domestic ...
Pathway Project, Lichfield, Gilbert, Beverley   +1 more
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