Results 51 to 60 of about 14,268,580 (205)

Uji Antikanker Isolat Bioaktif L-Asparaginase dari Kunyit Putih (Curcuma mangga Val.) terhadap Sel Kanker Serviks

Jurnal Kimia Sains dan Aplikasi, 2011
Kunyit putih (Curcuma mangga Val.) merupakan salah satu sumber L-asparaginase yang berpotensi sebagai bioaktif antikanker. Tujuan penelitian ini adalah untuk menentukan nilai LC50 dan potensi antikanker enzim L-asparaginase dari kunyit putih pada kultur ...
Citrawati Octavia Suprobo, Suprihati Suprihati, Wuryanti Wuryanti   +2 more
doaj   +1 more source

Imaging of Abdominal Complications in Children With Acute Lymphoblastic Leukaemia

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Acute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy and remains one of the most common causes of cancer‐related death in children and adolescents. Five‐year overall survival rates now exceed 90% with current multidrug chemotherapeutic regimens. This improvement, coupled with the toxicity of chemotherapy, has led to the
Luke R. Holmes, Rishi S. Kotecha, Derek J. Roebuck   +2 more
wiley   +1 more source

A Comparative Study on Pseudomonal and Bacillus L. asparaginases

Journal of Pure and Applied Microbiology, 2019
The enzyme L-asparaginase is commonly used in treatment of acute lymphoblastic leukemia (ALL). Due to its therapeutic importance and growing demands in medical and food industry much of the research have been focused to produce this enzyme with better ...
Nuzhath Fatima, Mohd Mazhar Uddin Khan, Noha Emad, Khadija Al-Khadir, Amany Marwan, Ayesha Alvi   +5 more
doaj   +1 more source

The new production method of bacterial L-asparaginase enzyme from different soil environments in Egypt as an anticancer agent

Ain Shams Medical Journal, 2022
BackgroundAsparagine degrading enzymes are necessary for the treatment of auxotrophic cancers such as acute lymphoblastic leukemia. Auxotrophic cancers do have not the ability to synthesize asparagine but normal cells can synthesize it.
Mohammed Kassab
doaj   +1 more source

Updated EAACI Statement on Drug Hypersensitivity Skin Testing: Methodology and Non‐Irritative Concentrations

Allergy, EarlyView.
ABSTRACT These updated EAACI guidelines aim to standardize skin testing methodologies for both immediate and non‐immediate drug hypersensitivity reactions. For immediate reactions, the optimal testing window is 4–6 weeks post‐reaction; whereas beyond 6 months, false‐negative results increase.
Annick Barbaud, Lene Heise Garvey, Elizabeth Phillips, Michael Ardern‐Jones, Sevim Bavbek, Patrizia Bonadonna, Jean‐Christoph Caubet, Ana‐Maria Copaescu, Valentina Gueli, Jose Julio Laguna, Ricardo Madrigal‐Burgaleta, Francesca Mori, Vito Sabato, Maria J Torres, Knut Brockow   +14 more
wiley   +1 more source

Isolation and Purification of L-Asparaginase from Persian Gulf Streptomyces Isolates and Evaluation of It’s Cloned Gene Expression in Escherichia Coli by Real-Time and SDS-PAGE [PDF]

Journal of Advanced Biomedical Sciences, 2020
Background & Objective: Asparaginase enzymes are effective in treating lymphoblastic leukemia cancer. This enzyme is isolated from bacterial sources and commercially available as an anticancer drug.
Hadiseh Soofer, Kumarss Amini, Seyed Mohammad Masoud Shushtarian   +2 more
doaj  

Radiation therapy for persistent or progressive mediastinal lymphoma after chemotherapy in FeLV‐positive cats: a retrospective case series of four cats

Australian Veterinary Journal, EarlyView.
Background Mediastinal lymphoma in feline leukaemia virus (FeLV)‐positive cats is associated with a poor prognosis, and therapeutic options may be limited when adequate disease control is not achieved with chemotherapy. The efficacy of radiation therapy in this setting has not been established.
A Uno, T Hasegawa, T Mori
wiley   +1 more source

Polyethylene Glycol-conjugated L-asparaginase versus native L-asparaginase in combination with standard agents for children with acute lymphoblastic leukemia in second bone marrow relapse: a Children's Oncology Group Study (POG 8866).

, 2022
BackgroundAdministration of L-asparaginase is limited by hypersensitivity reactions mediated by anti-asparaginase antibodies. To overcome this problem, native Escherichia coli L-asparaginase was conjugated to polyethylene glycol (PEG) to formulate PEG-L ...
Bernstein, Mark, Camitta, Bruce M, Asselin, Barbara, Pollock, Brad H, Kurtzberg, Joanne, Buchanan, George R   +5 more
core   +1 more source

Somatostatin therapy in L-asparaginase-induced pancreatitis

, 1994
L-Asparaginase-induced pancreatitis is an uncommon but potentially lethal complication. An 8-year-old girl with acute lymphoblastic leukaemia developed acute pancreatitis following treatment with asparaginase.
Y. F. Cheung, Lee, CW, K. L. Chan, Lau, YL, Yeung, CY, Cheung, YF, C. F. Chan, Chan, CF, Chan, KL, C. W. Lee, Y. L. Lau, C. Y. Yeung   +11 more
core   +1 more source

Emerging insights into amino acid metabolism in the heart: implications for cardiovascular diseases and therapeutic targeting

British Journal of Pharmacology, EarlyView.
As a metabolically versatile organ, the heart is capable of generating energy from a wide range of substrates. Although fatty acid and glucose metabolism in the heart have been extensively studied, the contribution of amino acid metabolism to cardiac physiology and disease is gaining increasing attention.
Tayyiba Azam, Hongyuan Zhang, Min Zi, Chen Chen, Junfang Wu, Andreas Papapetropoulos, Xin Wang   +6 more
wiley   +1 more source