Results 61 to 70 of about 14,268,580 (205)

Shared dysregulation of complement and phosphorylation pathways in the cerebrospinal fluid of encephalitis, Aicardi–Goutières syndrome, and autism

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Abstract Aim To identify shared and disorder‐specific molecular alterations across encephalitis, Aicardi–Goutières syndrome (AGS), and autism spectrum disorder (ASD) using cerebrospinal fluid (CSF) proteomics. Method In this cross‐sectional case–control study, mass‐spectrometry‐based proteomics was performed on archived CSF samples collected between ...
Omar H. Shadid   +8 more
wiley   +1 more source

L-Asparaginase Encapsulation into Asymmetric Permeable Polymersomes [PDF]

open access: yes, 2020
This work reports, for the encapsulation of l-asparaginase, an anticancer enzyme into hybrid PMPC25–PDPA70/PEO16–PBO22 asymmetric polymersomes previously developed by our group, with loading capacities with over 800 molecules per vesicle.
Poma, A   +6 more
core   +1 more source

STATISTICAL ANALYSIS OF GROWTH CONDITIONS OF NEWLY ISOLATE BACILLUS SP. PRODUCING L-ASPARAGINASE

open access: yesInternational Islamic University Malaysia Engineering Journal, 2020
The concentrations of nutrient elements together with several physical parameters were screened to find out the significant factors for the production of L-asparaginase from newly isolated strain, Bacillus sp. from Sg Klah, Hot Spring, Perak.
Dzun Noraini Jimat   +3 more
doaj   +1 more source

Toxicity of Cytarabine Intravenous Constant Rate Infusion in Cats With Lymphoma

open access: yesVeterinary and Comparative Oncology, EarlyView.
ABSTRACT Cytarabine intravenous constant rate infusion (IV CRI) toxicity in cats with lymphoma has not been well documented. We aimed to assess toxicities following cytarabine IV CRI as a single‐agent or within a multiagent protocol in cats with lymphoma. Medical records of cats with lymphoma treated with cytarabine IV CRI, with documented dose, route,
Rachel Hanford   +5 more
wiley   +1 more source

Purification, Characterization and Anticancer Activity of L-asparaginase Produced by Marine Aspergillus terreus

open access: yes, 2018
L-asparaginase (E.C.3.5.1.1) is an enzyme responsible for hydrolysis of L-asparagine into aspartic acid and ammonia, and has its significant applications in the therapeutics and food technology.
Sahar W.M. Hassan   +2 more
core   +1 more source

Venous Thromboembolism in Hematologic Malignancies: Incidence, Risk Factors, and the Role of Direct Oral Anticoagulants

open access: yesEuropean Journal of Haematology, Volume 117, Issue 6, Page 1421-1441, December 2026.
ABSTRACT Thrombotic events, particularly venous thromboembolism (VTE), are a significant source of morbidity and mortality among patients with hematologic malignancies. These patients face unique challenges due to treatment‐related complications such as thrombocytopenia, coagulopathy, and heightened bleeding risk.
Mario Biglietto   +12 more
wiley   +1 more source

Extracytoplasmic secretion of recombinant L-asparaginase constructs.

open access: yes, 2018
Extracytoplasmic secretion of recombinant L-asparaginase constructs.
Josell Ramirez-Paz (3852553)   +7 more
core   +1 more source

Plant NAOGAT (ArgJ) Structure Reveals Mechanism of Ornithine Biosynthesis, Preference for Acetylornithine and Susceptibility to Mangotoxin

open access: yesPlant, Cell &Environment, Volume 49, Issue 12, Page 10283-10300, December 2026.
ABSTRACT Arginine metabolism in plants is targeted by phytopathogens such as Pseudomonas syringae strains, which produce toxins that affect enzymes of plant arginine metabolism, causing devastating infections in crops. In this work, the structural and functional properties of plant N‐acetylornithine glutamate acetyltransferase (NAOGAT), the key ...
Maciej Nielipinski   +3 more
wiley   +1 more source

Fungal endophyte diversity in the leaves of the medicinal plant Myracrodruon urundeuva in a Brazilian dry tropical forest and their capacity to produce L-asparaginase

open access: yes, 2018
We studied the fungal endophyte community of the leaves of Myracrodruon urundeuva in Brazil along with their potential to produce L-asparaginase. In total, 187 endophytes were isolated.
Leticia Francisca da Silva (5789228)   +26 more
core   +1 more source

Guinea Pig Serum L-asparaginase: Purification, and Immunological Relationship to Liver L-asparaginase and Serum L-asparaginases in Other Mammals

open access: yes, 1995
l-asparaginase, an enzyme used in the treatment of acute lymphocytic leukemia, is found in the serum of only a few mammalian groups, including the guinea pig and its close relatives in the superfamily Cavioidea. This report describes the purification and
Clarke, F   +4 more
core   +2 more sources

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