L-Citrulline in Neonates: From Bench to Bed Side. [PDF]
Children (Basel)L-citrulline (L-CIT), a precursor to L-arginine (L-ARG), is a key contributor to the nitric oxide (NO) signaling pathway. Endothelial dysfunction, characterized by deficient nitric oxide synthesis, is implicated in the pathogenesis of various neonatal conditions such as necrotizing enterocolitis (NEC) and bronchopulmonary dysplasia (BPD) associated ...
Mascarenhas D +5 more
europepmc +3 more sources
Journal of Pharmacological Sciences, 2015 l-Citrulline is an effective precursor of l-arginine produced by the l-citrulline/l-arginine cycle, and it exerts beneficial effects on the cardiovascular system by supporting enhanced nitric oxide (NO) production.
Asami Mori +5 more
doaj +1 more source
Nutritional L-Citrulline and Tetrahydrobiopterin in Peripheral Artery Disease: A Phase II Randomized Trial (CIPER Study). [PDF]
JACC AdvSedding D +27 more
europepmc +2 more sources
Watermelon Juice: Potential Functional Drink for Sore Muscle Relief in Athletes [PDF]
, 2013 L-Citrulline is an excellent candidate to reduce muscle soreness, and watermelon is a fruit rich in this amino acid. This study investigated the potential of watermelon juice as a functional drink for athletes.
Aguayo, Encarna +4 more
core +2 more sources
l-Citrulline Supplementation-Increased Skeletal Muscle PGC-1α Expression Is Associated with Exercise Performance and Increased Skeletal Muscle Weight [PDF]
, 2018 1 Scopel‐citrulline has recently been reported as a more effective supplement for promoting intracellular nitric oxide (NO) production compared to l‐arginine.
Isoda Hiroko +3 more
core +2 more sources
Biochemical, physiological, and performance response of a functional watermelon juice enriched in L-citrulline during a half-marathon race [PDF]
, 2017 Background: Watermelon is a rich natural source of l-citrulline. This non-essential amino acid increases exercise performance. Objective: Evaluate the effect of Fashion watermelon juice enriched in l-citrulline (CWJ) (3.45 g per 500 mL) in physical ...
Armstrong RB +41 more
core +2 more sources
The Correlation of L-citrulline Levels with Blood Pressure in Severe Preeclampsia
Indonesian Biomedical Journal, 2020 BACKGROUND: Based on 'vascular disorder of pregnancy' terminology, preeclampsia primarily was not a hypertensive disorder, but a vascular disorder (general vasospasm) in pregnancy due to idiopathic etiology. The overall incidence of preeclampsia was 5-14%
Hudila Rifa Karmia +4 more
doaj +1 more source
Kidney mass reduction leads to L‐arginine metabolism‐dependent blood pressure increase in mice [PDF]
, 2018 Background Uninephrectomy (UNX) is performed for various reasons, including kidney cancer or donation. Kidneys being the main site of L‐arginine production in the body, we tested whether UNX mediated kidney mass reduction impacts L‐arginine metabolism
Fingerhut, Ralph +6 more
core +2 more sources
Frontiers in Immunology, 2018 Arginine is a semiessential amino acid in healthy adult human, but is essential for preterm, newborn or critically ill patients. Arginine can be supplied from our diet or de novo synthesis from citrulline. In conditions of sepsis or endotoxemia, arginine
Yi-Chen Lee +5 more
doaj +1 more source
Respiratory Research, 2012 Background Hyperoxia is shown to impair airway relaxation via limiting L-arginine bioavailability to nitric oxide synthase (NOS) and reducing NO production as a consequence. L-arginine can also be synthesized by L-citrulline recycling.
Sopi Ramadan B +7 more
doaj +1 more source