Results 1 to 10 of about 414,201 (353)

l-Lactate treatment by photosynthetic cyanobacteria expressing heterogeneous l-lactate dehydrogenase [PDF]

Scientific Reports, 2023
l-Lactate is a major waste compound in cultured animal cells. To develop a sustainable animal cell culture system, we aimed to study the consumption of l-lactate using a photosynthetic microorganism.
Yuichi Kato, Kosuke Inabe, Yuji Haraguchi, Tatsuya Shimizu, Akihiko Kondo, Tomohisa Hasunuma   +5 more
doaj   +5 more sources

The mitochondrial L-lactate dehydrogenase affair [PDF]

Frontiers in Neuroscience, 2014
The existence of a mitochondrial L-lactate dehydrogenase (m-L-LDH) suggested by Dianzani (1951), was shown by Baba and Sharma (1971) with the enzyme located in the mitochondrial matrix; later Brooks et al.
SALVATORE ePASSARELLA, Gianluca ePaventi, Roberto ePizzuto   +2 more
doaj   +7 more sources

Characterization of the L-lactate dehydrogenase from Aggregatibacter actinomycetemcomitans. [PDF]

PLoS ONE, 2009
Aggregatibacter actinomycetemcomitans is a Gram-negative opportunistic pathogen and the proposed causative agent of localized aggressive periodontitis. A.
Stacie A Brown, Marvin Whiteley
doaj   +18 more sources

NAD-Independent L-Lactate Dehydrogenase Required for L-Lactate Utilization in Pseudomonas stutzeri A1501. [PDF]

J Bacteriol, 2015
ABSTRACTNAD-independentl-lactate dehydrogenases (l-iLDHs) play important roles inl-lactate utilization of different organisms. All of the previously reportedl-iLDHs were flavoproteins that catalyze the oxidation ofl-lactate by the flavin mononucleotide (FMN)-dependent mechanism.
Gao C, Wang Y, Zhang Y, Lv M, Dou P, Xu P, Ma C.   +6 more
europepmc   +6 more sources

The Core of Allosteric Motion in Thermus caldophilus l-Lactate Dehydrogenase* [PDF]

Journal of Biological Chemistry, 2014
For Thermus caldophilus L-lactate dehydrogenase (TcLDH), fructose 1,6-bisphosphate (FBP) reduced the pyruvate S(0.5) value 10(3)-fold and increased the V(max) value 4-fold at 30 °C and pH 7.0, indicating that TcLDH has a much more T state-sided allosteric equilibrium than Thermus thermophilus L-lactate dehydrogenase, which has only two amino acid ...
Y. Ikehara, Kazuhito Arai, N. Furukawa, T. Ohno, T. Miyake, S. Fushinobu, M. Nakajima, A. Miyanaga, H. Taguchi   +8 more
semanticscholar   +5 more sources

Substrate Channeling via a Transient Protein-Protein Complex: The case of D-Glyceraldehyde-3-Phosphate Dehydrogenase and L-Lactate Dehydrogenase. [PDF]

Sci Rep, 2020
Substrate channeling studies have frequently failed to provide conclusive results due to poor understanding of this subtle phenomenon. We analyzed the mechanism of NADH-channeling from D-glyceraldehyde-3-phosphate dehydrogenase (GAPDH) to L-lactate ...
Svedružić ŽM, Odorčić I, Chang CH, Svedružić D.   +3 more
europepmc   +2 more sources

NAD-independent L-lactate dehydrogenase is required for L-lactate utilization in Pseudomonas stutzeri SDM. [PDF]

PLoS ONE, 2012
BACKGROUND: Various Pseudomonas strains can use L-lactate as their sole carbon source for growth. However, the L-lactate-utilizing enzymes in Pseudomonas have never been identified and further studied. METHODOLOGY/PRINCIPAL FINDINGS: An NAD-independent L-
Chao Gao, Tianyi Jiang, Peipei Dou, Cuiqing Ma, Lixiang Li, Jian Kong, Ping Xu   +6 more
doaj   +5 more sources

Enantioselective Biosynthesis of L-Phenyllactic Acid From Phenylpyruvic Acid In Vitro by L-Lactate Dehydrogenase Coupling With Glucose Dehydrogenase [PDF]

Frontiers in Bioengineering and Biotechnology, 2022
As a valuable versatile building block, L-phenyllactic acid (L-PLA) has numerous applications in the fields of agriculture, pharmaceuticals, and biodegradable plastics. However, both normally chemically synthesized and naturally occurring PLA are racemic,
Dong Zhang, Ting Zhang, Yuqing Lei, Wenqian Lin, Xingyi Chen, Minchen Wu   +5 more
doaj   +2 more sources

Lactic dehydrogenase enzyme and L-lactate in preeclampsia. A review [PDF]

, 2023
Background Preeclampsia is the most important hypertensive disease complicating human pregnancy in the world. It is a condition of placental origin with adverse effects on the placenta itself, the fetus and the mother. Its pathophysiology is complex and incompletely known.
Juan Gustavo Vázquez Rodríguez
openaire   +3 more sources

D- and L-lactate dehydrogenases during invertebrate evolution [PDF]

BMC Evolutionary Biology, 2008
The L-lactate and D-lactate dehydrogenases, which are involved in the reduction of pyruvate to L(-)-lactate and D(+)-lactate, belong to evolutionarily unrelated enzyme families. The genes encoding L-LDH have been used as a model for gene duplication due to the multiple paralogs found in eubacteria, archaebacteria, and eukaryotes.
Cristescu, M.E., Innes, D., Stillman, Jonathon H., Crease, T.J.   +3 more
openaire   +6 more sources