Results 41 to 50 of about 15,338,333 (210)
Metabolism of lysine in alpha-aminoadipic semialdehyde dehydrogenase-deficient fibroblasts: Evidence for an alternative pathway of pipecolic acid formation [PDF]
, 2010 The mammalian degradation of lysine is believed to proceed via two distinct routes, the saccharopine and the pipecolic acid routes, that ultimately converge at the level of α-aminoadipic semialdehyde (α-AASA).
Jakobs, C. +3 more
core +1 more source
Gut microbiota signatures and fecal metabolites in postmenopausal women with osteoporosis
Gut Pathogens, 2023 Background Women suffer from various distress and disturbances after menopause, including osteoporosis, a risk factor associated with multiple diseases. Altered gut microbiota has been implicated in postmenopausal osteoporosis.
Han Wang +11 more
doaj +1 more source
Inherited metabolic epilepsies–established diseases, new approaches
Epilepsia Open, EarlyView.Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
Journal of Translational Medicine, 2022 Background Antibody-mediated rejection (AMR) remains one of the major barriers for graft survival after kidney transplantation. Our previous study suggested a gut microbiota dysbiosis in kidney transplantation recipients with AMR.
Xin Li +5 more
doaj +1 more source
Journal of the Science of Food and Agriculture, EarlyView.Abstract BACKGROUND Plants harbor complex microbial communities that are fundamental to their health and productivity. Among them, endophytic fungi such as Purpureocillium lilacinum establish mutualistic associations, offering dual benefits as plant growth promoters and biocontrol agents.
Sana Bouzembila +5 more
wiley +1 more source
Biocatalytic Syntheis of L‐Pipecolic Acid by a Lysine Cyclodeaminase: Batch and Flow Reactors [PDF]
L-Pipecolic Acid (L-PA) is a valuable building block for the synthesis of pharmaceuticals such as anesthetics and immunosuppressants. Thus, more efficient and greener strategies are desired for its production.
Paradisi, Francesca +2 more
core +1 more source
Sensitivity and specificity of salivary pipecolic acid in head and neck squamous cell carcinoma [PDF]
, 2023 Aim: The aim of the present preliminary case-control study was to test the sensitivity and specificity of salivary pipecolic acid in predicting head and neck squamous cell carcinoma (HNSCC).
Alexander Thomas +12 more
core +1 more source
, 2016 A convergent approach to highly functionalized diketopiperazines (DKPs) using enantioenriched pipecolic acids is described. Scandium triflate-catalyzed [4 + 2] aza-annulation was employed to produce stereochemically well-defined building blocks. A resin “
John A. Porco, (2496631) +7 more
core +4 more sources
The Application of Amino Acids as a Sustainable Strategy for Managing Water Stress in Vineyards
Remote SensingWater scarcity increasingly threatens viticulture in the Macaronesian region due to climatic variability and recurrent droughts. This study evaluated the physiological and productive responses of grapevines (Vitis vinifera L.) to foliar applications of ...
Fabrício Lopes Macedo +7 more
doaj +1 more source
Frontiers in Veterinary Science, 2021 The effects of dietary supplementation with guava leaf extracts (GE) on intestinal barrier function and serum and fecal metabolome in weaned piglets challenged by enterotoxigenic Escherichia coli (ETEC) were investigated.
Dingfa Wang +3 more
doaj +1 more source