Results 61 to 70 of about 15,338,333 (210)

Multiple biochemical indices and metabolomics of Clonorchis sinensis provide a novel interpretation of biomarkers

Parasites & Vectors, 2022
Background Clonorchiasis, an infectious disease caused by the liver fluke Clonorchis sinensis, may lead to the development of liver and gallbladder diseases, and even cholangiocarcinoma (CCA).
Yang-Yuan Qiu, Qiao-Cheng Chang, Jun-Feng Gao, Ming-Jia Bao, Hai-Tao Luo, Jin-Ho Song, Sung-Jong Hong, Rui-Feng Mao, Yun-Yi Sun, Ying-Yu Chen, Ming-Yuan Liu, Chun-Ren Wang, Xiao-Lei Liu   +12 more
doaj   +1 more source

Metabolomics Based Biomarkers of Green Beans Intake

Molecular Nutrition &Food Research, Volume 70, Issue 19, 15 October 2026.
Identification of urinary food intake biomarkers of green beans using metabolomics applied to time response and dose response studies.This image was created with BioRender.com. ABSTRACT While there is considerable interest in legumes as a food source, there are no validated biomarkers for green beans (Phaseolus vulgaris, L.) intake.
Rebecca Finlay, Ya Gao, Qi Sun, Frank Hu, Jayne Woodside, Xiaofei Yin, Lorraine Brennan   +6 more
wiley   +1 more source

Methyl Jasmonate Seed Priming Mitigates the Defence‐Growth Trade‐Off and Tailors Plant Response to Specific Pests

Plant, Cell &Environment, Volume 49, Issue 10, Page 7558-7574, October 2026.
ABSTRACT Seed defence priming is emerging as a novel, cost‐efficient and environmentally safe tool for pest management. It has been proposed as a means to uncouple the defence‐growth trade‐off in plants by enhancing defence responses with minimal fitness costs, but the mechanisms underlying this role remain elusive.
Lucia Talavera‐Mateo, Adrian Sabater‐Gabriel, Alejandro Garcia, Marta Marina Perez‐Alonso, Rayko Halitschke, M. Estrella Santamaria   +5 more
wiley   +1 more source

841 L-PIPECOLIC ACID (PIP) CATABOLISM IN THE RABBIT: A MODEL FOR PIP METABOLISM IN MAN [PDF]

Pediatric Research, 1985
Elevated circulating levels of PIP, a putative neurotransmitter, are found in Zellweger syndrome (ZS) and hyperpipecolic acidemia (HPA). As these elevations and the mammalian PIP degradation pathway are poorly understood, we studied L-PIP degradation to α-aminoadipic acid (AAA) in the rabbit.
Stephanie J Mihalik, William J Rhead, Jean Robillard   +2 more
openaire   +1 more source

Dynamic changes of postprandial plasma metabolites after intake of corn-soybean meal or casein-starch diets in growing pigs

Journal of Animal Science and Biotechnology, 2019
Background Postprandial nutrients utilization and metabolism of a certain diet is a complicated process. The metabolic feature of pigs after intake of corn-soybean meal or casein-starch diets are largely unknown.
Tiantian Li, Shimeng Huang, Juntao Li, Hu Liu, Wei Wang, Na Li, Meng Shi, Shiyu Tao, Shuai Zhang, Zhen Li, Junjun Wang   +10 more
doaj   +1 more source

Experiencing 50 Years of Synergistic Development in Structural Biology and Enzymology

Journal of the Chinese Chemical Society, Volume 73, Issue 9, Page 1291-1306, September 2026.
Picture of Sunney Chan with Academia Sinica (AS) President James C. Liao and three Vice Presidents: Shin‐Kun Peng (left one), Tang K. Tang (right one), and Mei‐Yin Chou (right 2), taken at the annual Chinese New Year's Banquet of AS, February 7, 2025. This was likely Sunney's last appearance in formal activities of AS.
Ming‐Daw Tsai
wiley   +1 more source

Advances in large DNA fragment assembly for microbial cell factory engineering

Quantitative Biology, Volume 14, Issue 3, September 2026.
Abstract The efficient, rapid, and reliable assembly of DNA fragments is essential for advancing metabolic engineering and synthetic biology. With the rapid advancement of DNA synthesis and assembly technologies, the scale of DNA assembly has expanded from single genes to metabolic pathways and even genomes.
Yu Zhang, Wenqian Liu, Dongyuan Cheng, Jiazhang Lian, Xian Fu, Yue Shen   +5 more
wiley   +1 more source

An Efficient Approach to the Family of 4-Substituted Pipecolic Acids. Syntheses of 4-Oxo, cis-4-Hydroxy-, and trans-4-Hydroxy-L-pipecolic Acids from L-Aspartic Acid

, 1995
Golubev A, Sewald N, Burger K. An Efficient Approach to the Family of 4-Substituted Pipecolic Acids. Syntheses of 4-Oxo, cis-4-Hydroxy-, and trans-4-Hydroxy-L-pipecolic Acids from L-Aspartic Acid. Tetrahedron Letters.
Burger, Klaus, Golubev, Alexander, Sewald, Norbert ; https://orcid.org/   +2 more
core   +1 more source

Dengue Virus Molecular Targets and Antiviral Drug Development: Advances, Challenges and Therapeutic Perspectives

ChemistrySelect, Volume 11, Issue 33, 1 September 2026.
This narrative review analyzes DENV molecular targets, including structural proteins (C, prM/M, E), non‐structural components (NS1NS5), and host factors, alongside small‐molecule candidates in preclinical and clinical phases. Owing to high structural conservation, the NS2B‐NS3 protease and NS5 (RdRp/MTase) remain primary drug discovery focuses, while ...
Aryane Lucia da Silva Aguiar De Oliveira, José Arion Da Silva Moura, Pedro César de Souza, Marcelo Arthur Dias da Costa Santana, Matheus Vinicius Guimarães de Melo, Douglas Carvalho Francisco Viana, Marina Galdino Da Rocha Pitta, Isabella Luiza Ralph de Oliveira, Maira Galdino Da Rocha Pitta   +8 more
wiley   +1 more source

Asymmetric synthesis of pipecolic acid and derivatives

, 2012
The nonproteinogenic α-amino acid, l-pipecolic acid and its derivatives are components of a wide range of pharmacologically active compounds. The significant biological activity of these compounds has resulted in the development of many synthetic ...
Cant, A., Sutherland, A.
core   +1 more source