Results 81 to 90 of about 15,338,333 (210)

Structure and dynamics of macrophage infectivity potentiator proteins from pathogenic bacteria and protozoans bound to fluorinated pipecolic acid inhibitors [PDF]

Macrophage infectivity potentiator (MIP) proteins are present in many microbial pathogens, both of pro- and of eukaryotic origin. MIP proteins play important roles in microbial virulence, facilitating processes like host cell infection, pathogen ...
Jean-Martin, Harder, Albert, Guskov, Theresa, Lohr, Nicholas, Harmer, Christoph, Wiedemann, Ulrike , Holzgrabe, Victor Hugo, Pérez Carrillo, Jacob, Whittaker, Marina, Dajka, Benedikt, Goretzki, Ute, Hellmich, Anil, Jamithireddy, Benesh, Joseph   +12 more
core   +2 more sources

Transcriptomic Screening of Alternaria oxytropis Isolated from Locoweed Plants for Genes Involved in Mycotoxin Swainsonine Production

Journal of Fungi
Locoweed is a collective name for a variety of plants, such as Oxytropis and Astragalus L. When these plants are infected by some fungi or endophytes, they will produce an alkaloid (swainsonine) that is harmful to livestock.
Shuangjie Yuan, Qingmei Zhao, Kun Yu, Ying Gao, Zhengbing Ma, Huanyu Li, Yongtao Yu   +6 more
doaj   +1 more source

Rational Design of the Soluble Variant of l-Pipecolic Acid Hydroxylase using the α-Helix Rule and the Hydropathy Contradiction Rule. [PDF]

ACS Omega, 2022
Shinoda S, Itakura A, Sasano H, Miyake R, Kawabata H, Asano Y.   +5 more
europepmc   +1 more source

Pyridoxine-Dependent Epilepsy and Pipecolic Acid

, 2000
Two neonates with pyridoxine-dependent epilepsy and significant elevation of pipecolic acid in plasma and CSF are reported from the University Hospital Vienna ...
J Gordon Millichap
core   +1 more source

Synthesis of enantiopure α-Tfm-proline and α-Tfm-pipecolic acid from oxazolo-pyrrolidines and -piperidines

, 2021
International audienceScalable synthesis of enantiopure ( R ) and ( S )-α-Tfm-proline and α-Tfm-pipecolic ...
Gadais, Charlène, Diarra, Sitan, Sanchez, Clément,, Bordessa, Andrea, Sanchez, Clément, A, Lensen, Nathalie, Brigaud, Thierry, Chelain, Evelyne   +7 more
core   +1 more source

Pipecolic Acid-Catalyzed Direct Asymmetric Mannich Reactions

, 2016
Mannich reactions between aldehydes and N-p-methoxyphenyl-protected α-imino ethyl glyoxylate have been performed using (S)-pipecolic acid as catalyst. The reactions give both syn- and anti-products (dr = 1.4−2:1) with high enantioselectivities (>98% ee).
Fujie Tanaka (2329276), Rajee Thayumanavan (2649142), Paul Ha-Yeon Cheong (1642720), K. N. Houk (1247004), Haile Zhang (2317696), Carlos F. Barbas (19478)   +5 more
core   +1 more source

An economically and environmentally acceptable synthesis of chiral drug intermediate l-pipecolic acid from biomass-derived lysine via artificially engineered microbes

, 2018
Deficiency in petroleum resources and increasing environmental concerns have pushed a bio-based economy to be built, employing a highly reproducible, metal contaminant free, sustainable and green biomanufacturing method.
Qinhong Wang, Yuding Huang, Wujiu Chen, Jie Cheng, Le Mi, Dan Wang   +5 more
core   +1 more source

Pipecolic Acid and Novel Insights Into Cerebral Malaria [PDF]

Cerebral malaria (CM), a severe manifestation of Plasmodium infection, prompts our investigation into the nuanced role of pipecolic acid in its pathophysiology.
Mensah, Akua E
core   +1 more source

Conversion of D-Lysine to ʟ-Lysine via L-Pipecolic Acid in Neurospora crassa

Zeitschrift für Naturforschung C, 1975
Abstract Neurospora crassa, Biosynthesis, ᴅ-Lysine, ʟ-Lysine, Role of ʟ-Pipecolic Acid Neurospora crassa converts ᴅ-lysine to ʟ-pipecolic acid and the latter to ʟ-lysine by a pathway outlined herein and different from mechanisms hitherto known to be involved in interconversions of enantiomers of amino acids.
W.-U. Müller, E. Leistner
openaire   +1 more source

The lysine-ketoglutarate reductase-saccharopine dehydrogenase is involved in the osmo-induced synthesis of pipecolic acid in rapeseed leaf tissus

, 2006
International audienceHigher plant responses to abiotic stresses are associated with physiological and biochemical changes triggering a number of metabolic adjustments.
Larher, François, R., Deleu, Carole, Bouchereau, Alain, Moulin, M.   +3 more
core   +1 more source