Results 91 to 100 of about 15,338,333 (210)

Structural basis for recognition of L-lysine, L-ornithine, and L-2,4-diamino butyric acid by lysine cyclodeaminase [PDF]

, 2018
L-pipecolic acid is a non-protein amino acid commonly found in plants, animals, and microorganisms. It is a well-known precursor to numerous microbial secondary metabolites and pharmaceuticals, including anticancer agents, immunosuppressants, and several
H.H. Lee, Kim, Yong Hwan, Min, Kyungjin, A. Matsuura, Lee, Hyung Ho, H.J. Yoon, Y.H. Kim, Yoon, Hye-Jin, Matsuura, Atsushi, K.J. Min   +9 more
core   +1 more source

Synthesis of Extracellular L-lysine-α-oxidase along with Degrading Enzymes by Trichoderma cf. aureoviride Rifai VKM F-4268D: Role in Biocontrol and Systemic Plant Resistance

Journal of Fungi
When cultivating on wheat bran or deactivated fungal mycelium as a model of “natural growth”, the ability of Trichoderma to synthesize extracellular L-lysine-α-oxidase (LysO) simultaneously with cell-wall-degrading enzymes (proteases, xylanase ...
Anna Yu. Arinbasarova, Alexander S. Botin, Alexander G. Medentsev, Kirill V. Makrushin, Alexandre A. Vetcher, Yaroslav M. Stanishevskiy   +5 more
doaj   +1 more source

Seven conformers of pipecolic acid identified in the gas phase [PDF]

, 2016
The multiconformational landscape of the non-proteinogenic cyclic amino acid pipecolic acid has been explored in the gas phase. Solid pipecolic acid (m.p.
Alonso, José L.
core  

Optimized conversion of L-lysine to L-pipecolic acid using recombinant lysine cyclodeaminase from Streptomyces pristinaespiralis

, 2015
Lysine cyclodeaminase (LCD; EC: 4.3.1.28) is a beta-nicotinamide adenine dinucleotide-dependent enzyme that catalyzes the beta-deamination of L-lysine to produce L-pipecolate.
Cho, Dae Haeng, Kim, Yong Hwan, Jeong, Seong Wook, Byun, Sung Min   +3 more
core   +1 more source

Integrated network pharmacology and metabolomics to study the potential mechanism of Jiawei Yinchenhao decoction in chronic hepatitis B

Heliyon
Chronic hepatitis B infection (CHB) is a major risk factor for the development of hepatocellular carcinoma (HCC) globally and continues to pose a significant global health challenge. Jiawei Yinchenhao decoction (JWYCH) is a modified version of Yinchenhao
Xinyi Xu, Jin Liu, Xue Li, QuanSheng Feng, Yue Su   +4 more
doaj   +1 more source

Ethanol extract of propolis relieves exercise-induced fatigue via modulating the metabolites and gut microbiota in mice

Frontiers in Nutrition
BackgroundPropolis, a natural mixture rich in bioactive compounds, has shown the potential to relieve exercise-induced fatigue. However, the underlying mechanism remains unclear.
Shan Huang, Xiaofei Yang, Jingxuan Ma, Chen Li, Yajing Wang, Zhaoxia Wu   +5 more
doaj   +1 more source

Multi-omics reveals microbiota, metabolite, and immunological heterogeneity of age-related endotypes in type 1 diabetes

Signal Transduction and Targeted Therapy
Type 1 diabetes (T1D) exhibits age-related heterogeneity in clinical progression and immune pathology, yet the underlying molecular mechanisms remain poorly understood. Here, we integrate microbiome, metabolome, lipidome, and transcriptome profiling from
Lanxin Pan, Huiling Tan, Tong Yue, Yu Ding, Zhaohe Gu, Xulin Wang, Jing Wang, Tian Wei, Xiaoya Zhang, Yu Shi, Shiru Chang, Chuang Guo, Xueying Zheng, Jianping Weng   +13 more
doaj   +1 more source

Pipecolic Acid, a Drought Stress Modulator, Boosts Chlorophyll Assimilation, Photosynthetic Performance, Redox Homeostasis, and Osmotic Adjustment of Drought-Affected Hordeum vulgare L. Seedlings

Plants
While pipecolic acid (Pip) mediates morpho-physiological and molecular responses during biotic stress, its roles under drought remain an inexpressible mystery.
Nagihan Aktas, Saad Farouk, Amal Ahmed Mohammed Al-Ghamdi, Ahmed S. Alenazi, Mona Abdulaziz Labeed AlMalki, Burcu Seckin Dinler   +5 more
doaj   +1 more source

Recycling the Versatile Pipecolic Linker

, 2010
International audienceThe Pipecolic linker is a new highly versatile handle which immobilizes on solid support through a carboxylic acid function a wide range of amines, alcohols, and hydrazines.
Jean Martinez, Pawlowski, Maciej, Martinez, Jean, Sanchez, Pierre, Nicolas Masurier, Muriel Amblard, Christine Enjalbal, Pawel Zajdel, Enjalbal, Christine, Amblard, Muriel, Subra, Gilles, Gilles Subra, Nomezine, Gaël, Pierre Sanchez, Kreiter, Aude, Zajdel, Pawel, Maciej Pawlowski, Aude Kreiter, Masurier, Nicolas, Gaël Nomezine   +19 more
core   +1 more source

Integrated Transcriptomic and Metabolomic Provide Insights into Strawberry Bioactive Compounds and Antioxidant Activities Under Varying Ecological Conditions

Horticulturae
Strawberries are nutrient-rich fruits containing beneficial phytochemicals and bioactive compounds with significant health benefits. Among secondary metabolites, the polyphenolic compounds have been extensively studied.
Mingzheng Duan, Huaizheng Wang, Kangjian Song, Honggao Liu, Shu Jiang, Jieming Feng, Shiping Jiang, Muhammad Junaid Rao, Abdul Rauf, Muhammad Ikram, Muhammad Faizan Khurram, Maryam Tahira, Shunqiang Yang, Xiande Duan   +13 more
doaj   +1 more source