Results 81 to 90 of about 6,477 (171)

Peptide selection via phage display to inhibit Leishmania-macrophage interactions

Frontiers in Microbiology
IntroductionLeishmaniasis comprises a complex group of diseases caused by protozoan parasites from the Leishmania genus, presenting a significant threat to human health.
Juliane Buzzon Meneghesso Verga, Márcia A. S. Graminha, Marcelo Jacobs-Lorena, Sung-Jae Cha   +3 more
doaj   +1 more source

Antileishmanial activity of lapachol analogues

Memorias do Instituto Oswaldo Cruz, 2004
The antileishmanial activity of lapachol, isolapachol, and dihydrolapachol, along with soluble derivatives (potassium salt) and acetate was obtained. All the compounds were assayed against metacyclic promastigotes of two different species of Leishmania ...
Nadja MF Lima, Clariane S Correia, Leonor L Leon, Gérzia MC Machado, Maria de Fátima Madeira, Antônio Euzébio G Santana, Marília OF Goulart   +6 more
doaj   +1 more source

Toll-like receptors 2, 4, and 9 expressions over the entire clinical and immunopathological spectrum of American cutaneous leishmaniasis due to Leishmania(V.) braziliensis and Leishmania (L.) amazonensis.

PLoS ONE, 2018
Leishmania (V.) braziliensis and Leishmania(L.) amazonensis are the most pathogenic agents of American Cutaneous Leishmaniasis in Brazil, causing a wide spectrum of clinical and immunopathological manifestations, including: localized cutaneous ...
Marliane Batista Campos, Luciana Vieira do Rêgo Lima, Luciana Vieira do Rêgo Lima, Ana Carolina Stocco de Lima, Thiago Vasconcelos Dos Santos, Patrícia Karla Santos Ramos, Claudia Maria de Castro Gomes, Fernando Tobias Silveira   +7 more
doaj   +1 more source

Insights into Divergent Leishmaniasis Pathogenesis: A Quantitative Flagellar Proteomic Comparison of L. mexicana, L. amazonensis, and L. infantum

Microorganisms
Leishmaniasis, a neglected tropical disease endemic to 98 countries, affects more than 300 million people worldwide. The disease is transmitted through the bite of infected female phlebotomine sand flies harboring Leishmania parasites. Although infection initiates at the cutaneous inoculation site, Leishmania species exhibit distinct tissue tropisms ...
Diya Lalu Patel, Seok-Young Kim, Olga Uchakina, Niani Angelle Clermont, Jean Byung Hyun, Aleem Damji Patni, Manas Paresh Patel, Shan Khan, Dhruv K. Rana, Chan Hyun Na, Sung-Jae Cha   +10 more
openaire   +1 more source

Modulation of fibroblast behavior by Leishmania: a pathway to understanding disease progression in cutaneous leishmaniasis

BMC Microbiology
Leishmaniasis is a parasitic infection caused by obligatory intracellular protozoa of the Leishmania genus. Macrophages are the main cell for Leishmania parasites that play a key role in immune response against it.
Tarcisio Navegante de Queiroz Filho, Brenda Furtado Costa, Ana Paula Drummond Rodrigues   +2 more
doaj   +1 more source

Characterization of Leishmania (L.) amazonensis oligopeptidase B and its role in macrophage infection. [PDF]

Parasitology, 2022
Barbosa GR, Marana SR, Stolf BS.
europepmc   +1 more source

Inoculation of the Leishmania infantum HSP70-II Null Mutant Induces Long-Term Protection against L. amazonensis Infection in BALB/c Mice. [PDF]

Microorganisms, 2021
Soto M, Ramírez L, Solana JC, Cook ECL, Hernández-García E, Requena JM, Iborra S.   +6 more
europepmc   +1 more source

Leishmania amazonensis in dog with clinical diagnosis of visceral leishmaniasis in Paraná State, Brazil – a case report
Leishmania amazonensis em cão com quadro clínico de leishmaniose visceral no Estado do Paraná, Brasil – relato de caso

Semina: Ciências Agrárias, 2012
Leishmaniasis are antropozoonoses involving various species of Leishmania and hosts, with variable clinical presentations and considered of great importance to public health.
Patrícia Mendes Pereira, Regina Mitsuka Breganó, Eloiza Teles Caldart, Italmar Teodorico Navarro, Valdair Elemar Camargo Junior, Aline Rafaeli Hoffmann   +5 more
doaj  

Caffeic Acid Phenethyl Ester (CAPE) Inhibits Arginase Activity and Growth of Leishmania amazonensis Promastigotes and Intracellular Amastigotes

Pathogens
Caffeic acid phenethyl ester (CAPE) is a polyphenol produced by many plants and is found in red and green propolis. Here, we evaluated the antileishmanial activity of this natural product against Leishmania amazonensis. CAPE exhibited IC50 values of 8.07
Edson Roberto da Silva, André Mesquita, Claudia do Carmo Maquiaveli   +2 more
doaj   +1 more source

Effect of natural naphthoquinones in BALB/c mice infected with Leishmania amazonensis and L. venezuelensis.

Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1992
Plumbagin, 3,3'-biplumbagin and 8,8'-biplumbagin are naphthoquinones isolated by activity-directed fractionation from a Bolivian plant, Pera benensis, used in folk medicine as treatment of cutaneous leishmaniasis caused by Leishmania braziliensis. BALB/c mice were infected with L. mexicana or L.
/Fournet, Alain, Barrios, A.A., Munoz, V., Hocquemiller, R., Cavé, A.   +4 more
openaire   +2 more sources