Results 81 to 90 of about 13,174,260 (209)
Effects of medicinal plant extracts on growth of Leishmania (L.) amazonensis and Trypanosoma cruzi [PDF]
Revista Brasileira de Ciências Farmacêuticas, 2005 This study describes the screening of extracts obtained from 19 species of plants used in Brazilian traditional medicine for treatment of a variety of diseases. The extracts were tested against axenic amastigote and promastigote forms of Leishmania (L.) amazonensis, and epimastigote forms of Trypanosoma cruzi in vitro at a concentration of 100 mg/ml ...
Luize, Patrícia Shima +8 more
openaire +2 more sources
Osteopontin in the host response to Leishmania amazonensis
BMC Microbiology, 2019 Background Leishmania (L.) spp are intracellular eukaryotic parasites responsible for cutaneous or visceral leishmaniasis, replicating predominantly in macrophages (MF). In C57BL/6 mice virulence with L. amazonensis has been associated with inhibition of
Emilie Giraud +5 more
doaj +1 more source
Chemical Biology &Drug Design, Volume 108, Issue 2, August 2026.This work highlights the satisfactory pharmacokinetic profile of two benzenesulfonylpiperazine lead candidates, followed by in vivo assessment in a murine model of visceral leishmaniasis. This assessment identified compound 2 as moderately active at a lower dose, but its efficacy increased at higher doses, though with concerns regarding safety.
Thibault Joseph William Jacques Dit Lapierre +13 more
wiley +1 more source
, 2014 aSNPs found in the reference strain (L. amazonensis M2269) compared to the isolate L. amazonensis 2506 and to the MF150.3 resistant clones (1–3) are indicated. Non-synonymous SNPs are in bold.bGene size in base pairs (bp).
Silvia R. B. Uliana (240903) +3 more
core +1 more source
Memorias do Instituto Oswaldo Cruz, 1992 Immunoblot analysis was used to investigate antigenic differences among clinical isolates of Leishmania amazonensis and their role in the etiology of the diseases. Western blots of promastigote homogenates were analyzed with either monoclonal antibodies (
Leonor L. Leon +4 more
doaj +1 more source
Thymus and Leishmania at the Crossroads: Autoimmunity and Cancer
Immunology, Volume 178, Issue 3, Page 377-386, July 2026.Conceptual ‘Crossroads Model’ linking Leishmania, thymic infection and immune dysregulation: an integrative model is proposed in which Leishmania infection disrupts thymic architecture and stromal–thymocyte interactions. These alterations converge to promote defective tolerance, increased autoimmune risk and a microenvironment permissive to malignant ...
Alef Batista Bezerra Barros +5 more
wiley +1 more source
Drosophila Model of Leishmania amazonensis Infection
, 2017 This protocol describes how to generate and harvest antibody-free L. amazonensis amastigotes, and how to infect adult Drosophila melanogaster with these parasites.
Kendi Okuda, Neal Silverman
core +1 more source
Memorias do Instituto Oswaldo Cruz, 1982 The culture forms of L. mexicana pifanoi (LRC L-90), L. mexicana mexicana (LRC L-94, M-379); L. braziliensis braziliensis (LRC L-77, L-1, M-2903, H-LSS) and L.
J. Schottelius +1 more
doaj +1 more source
International Wound Journal, Volume 23, Issue 6, June 2026.ABSTRACT Chronic wounds, exacerbated by infection, aging, diabetes, and oxidative stress, remain a significant challenge in clinical management and impose a substantial burden on healthcare systems. This study presents oregano‐derived plasma polymers (OPP) as a multifunctional surface coating for advanced wound healing applications.
Jesus Romo‐Rico +7 more
wiley +1 more source
Liposomes encapsulating L. amazonensis promastigotes.
, 2015 The liposome membrane is composed of a EPC-PEG lipid mixture. Five million of L. amazonensis promastigotes per ml were used for the encapsulation process. (A) Liposomes containing multiple parasites. (B) Liposome with a single parasite with its flagellum
Annie Viallat (779682) +4 more
core +1 more source