Results 61 to 70 of about 6,477 (171)

Canine Leishmaniasis in Rio de Janeiro, Brazil (2000–2015): Taxonomic Characterisation of Etiological Agents and Geospatial Case Analysis

Zoonoses and Public Health, Volume 73, Issue 4, Page 314-325, June 2026.
ABSTRACT Introduction Canine Leishmaniasis is a vector‐borne zoonotic disease caused by several species of protozoa of the genus Leishmania. In the state of Rio de Janeiro (RJ), Leishmania braziliensis is the most prevalent species causing tegumentary leishmaniasis (TL) and Leishmania infantum is the main causative agent of visceral leishmaniasis (VL).
Luciana de Freitas Campos Miranda, Laryssa Fabiano do Rosário Coelho, Samanta Cristina das Chagas Xavier, Artur Augusto Velho Mendes Junior, Renan Nunes Albuquerque, Aline Fagundes da Silva, Andreza Pain Marcelino, Fernanda Nunes Santos, Sandro Antonio Pereira, Rodrigo Caldas Menezes, Armando de Oliveira Schubach   +10 more
wiley   +1 more source

Biological activities of 1,4-naphthoquinones derivatives against T. cruzi and L. amazonensis

Revista Colombiana de Ciencias Químico-Farmacéuticas, 2022
Introduction: Chagas disease and Leishmaniasis are neglected diseases caused bythe Trypanosoma cruzi and kentoplastid parasites Leishmania spp. Parasitic diseasescause great impact on social and economic, affecting millions of people in the worldand represent a major global health problem.
Adriano Olímpio da Silva, Rosangela Da Silva Lopes, Aline Alves dos Santos Naujorks, Celso Vataru Nakamura, Dênis Pires de Lima   +4 more
openaire   +1 more source

In vitro evaluation of the anti-leishmanial activity and toxicity of PK11195

Memorias do Instituto Oswaldo Cruz, 2018
BACKGROUND Leishmaniasis, one of the most neglected diseases, is a serious public health problem in many countries, including Brazil. Currently available treatments require long-term use and have serious side effects, necessitating the development of new
Carlos Eduardo Sampaio Guedes, Beatriz Rocha Simões Dias, Antonio Luis de Oliveira Almeida Petersen, Kercia Pinheiro Cruz, Niara de Jesus Almeida, Daniela Rodrigues Andrade, Juliana Perrone Bezerra de Menezes, Valéria de Matos Borges, Patricia Sampaio Tavares Veras   +8 more
doaj   +1 more source

Structural basis of secreted acid phosphatase polymerization in the Leishmania parasite

Protein Science, Volume 35, Issue 5, May 2026.
Abstract Enzymes that assemble into filaments typically transition between protomeric and polymeric states in response to cellular conditions. In contrast, the secreted acid phosphatase (SAP) of Leishmania, one of the most abundant extracellular glycoproteins produced by the parasite and regarded as a major virulence factor in the neglected tropical ...
Priyanka Bose, Irit Dahan, Alexander Upcher, Ran Zalk, Iris Grossman‐Haham   +4 more
wiley   +1 more source

Effects of medicinal plant extracts on growth of Leishmania (L.) amazonensis and Trypanosoma cruzi [PDF]

Revista Brasileira de Ciências Farmacêuticas, 2005
This study describes the screening of extracts obtained from 19 species of plants used in Brazilian traditional medicine for treatment of a variety of diseases. The extracts were tested against axenic amastigote and promastigote forms of Leishmania (L.) amazonensis, and epimastigote forms of Trypanosoma cruzi in vitro at a concentration of 100 mg/ml ...
Luize, Patrícia Shima, Tiuman, Tatiana Shioji, Morello, Luis Gustavo, Maza, Paloma Korehiza, Ueda-Nakamura, Tânia, Dias Filho, Benedito Prado, Cortez, Diógenes Aparício Garcia, Mello, João Carlos Palazzo de, Nakamura, Celso Vataru   +8 more
openaire   +2 more sources

Osteopontin in the host response to Leishmania amazonensis

BMC Microbiology, 2019
Background Leishmania (L.) spp are intracellular eukaryotic parasites responsible for cutaneous or visceral leishmaniasis, replicating predominantly in macrophages (MF). In C57BL/6 mice virulence with L. amazonensis has been associated with inhibition of
Emilie Giraud, Eline Rouault, Laurence Fiette, Jean-Hervé Colle, Despoina Smirlis, Evie Melanitou   +5 more
doaj   +1 more source

Nano‐Encapsulated Cinnamomum cassia Essential Oil in Combination With Fluconazole Exhibits Synergistic Activity Against Fluconazole‐Resistant Nakaseomyces glabratus and Pichia kudriavzevii

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Nano‐encapsulated Cinnamomum cassia essential oil (nano‐CC‐EO) showed in vitro antifungal activity against fluconazole‐resistant Nakaseomyces glabratus and Pichia kudriavzevii clinical isolates. Checkerboard assays revealed synergistic or additive interactions between nano‐CC‐EO and fluconazole in several isolates, without evidence of antagonism. These
Mehrdad Seifi, Mohammad Ali Esfandiary, Negar Hemmati, Javad Malakootikhah, Donya Nikaein, Ali Reza Khosravi   +5 more
wiley   +1 more source

Studies on the relationship between lectin binding carbohydrates and different strains of Leishmania from the New World

Memorias do Instituto Oswaldo Cruz, 1982
The culture forms of L. mexicana pifanoi (LRC L-90), L. mexicana mexicana (LRC L-94, M-379); L. braziliensis braziliensis (LRC L-77, L-1, M-2903, H-LSS) and L.
J. Schottelius, S. C. Gonçalves da Costa   +1 more
doaj   +1 more source

Antigenic differences among Leishmania amazonensis isolates and their relationship with distinct clinical forms of the disease

Memorias do Instituto Oswaldo Cruz, 1992
Immunoblot analysis was used to investigate antigenic differences among clinical isolates of Leishmania amazonensis and their role in the etiology of the diseases. Western blots of promastigote homogenates were analyzed with either monoclonal antibodies (
Leonor L. Leon, Gerzia M. C. Machado, Aldina Barral, Luiz E. de Carvalho-Paes, Gabriel Grimaldi Júnior   +4 more
doaj   +1 more source

Tegumentary Leishmaniasis Associated With Immune Reconstitution in an HIV Patient—A Case Report

Parasite Immunology, Volume 48, Issue 5, May 2026.
ABSTRACT HIV‐associated Immune Reconstitution Inflammatory Syndrome (IRIS) may significantly alter the immunopathological presentation of American Tegumentary Leishmaniasis (ATL), occasionally causing paradoxical clinical exacerbations. We report the long‐term follow‐up of a 39‐year‐old female coinfected with HIV and disseminated mucocutaneous ...
Marilia Brasil Xavier, Claudia Maria de Castro Gomes, Rita Catarina Medeiros Sousa, Edna Aoba Yassui Ishikawa, Elza Baía de Brito, Silvia Ferreira Rodrigues Müller, Lucas dos Santos Fontes, João Augusto Gomes de Souza Monteiro de Brito, Larissa dos Santos Alcantara, Carlos Eduardo Pereira Corbett   +9 more
wiley   +1 more source