Results 61 to 70 of about 13,174,260 (209)
Innate Resistance to Leishmania amazonensis Infection in Rat Is Dependent on NOS2
Frontiers in Microbiology, 2021 Leishmania infection causes diverse clinical manifestations in humans. The disease outcome is complicated by the combination of many host and parasite factors.
Yun-Fu Chen +11 more
doaj +1 more source
ChemistrySelect, Volume 11, Issue 40, 27 October 2026.New anthranilate–naphthoquinone hybrids display potent inhibition of Leishmania (L.) amazonensis with low host cell toxicity. Molecular docking reveals key interactions with TR, GP63, and PTR1, suggesting a multitarget mechanism that contributes to parasite death.
Eduardo Miranda da Silva Magesfeste +7 more
wiley +1 more source
, 2013 Transcriptional signatures accounting for cholesterol metabolism in dendritic leukocytes (DLs) hosting live L. amazonensis amastigotes.
Marie-Christine Prévost (2280838) +4 more
core +1 more source
Cadernos de Saúde Pública, 1996 Inquérito envolvendo leishmaniose e doença de Chagas, por meio da Reação de Imunofluorescência Indireta, foi realizado com soros de 331 cães de Uberlândia e Coromandel, Municípios do Estado de Minas Gerais, Brasil. Para tal inquérito, utilizaram-se, como
Paula Guardenho Maywald +3 more
doaj +1 more source
Perillic Acid Synergizes With the Miltefosine Leishmanicidal Effect Against Leishmania amazonensis
Parasite Immunology, Volume 48, Issue 10, October 2026.ABSTRACT Perillic acid (PA), a monocyclic monoterpene derived from limonene, was evaluated for its leishmanicidal activity alone and in combination with miltefosine, as well as in its microemulsion‐based formulation. PA demonstrated synergistic activity with miltefosine and was effective against both promastigote and amastigote forms of Leishmania ...
C. Ferreira +6 more
wiley +1 more source
Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.Chamomile (Matricaria chamomilla) extract significantly reduced oocyst shedding and intestinal lesions in immunosuppressed mice infected with Cryptosporidium parvum, while enhancing antioxidant defences (GPx, TAC). These findings suggest chamomile as a promising phytotherapeutic agent for cryptosporidiosis. ABSTRACT Background Cryptosporidiosis, caused
Kousha Kiani +3 more
wiley +1 more source
Photodiagnosis and Photodynamic Therapy, 2018 This study investigated the activity of photosensitive phthalocyanines on promastigotes and amastigotes of Leishmania (L.) amazonensis. Aluminum phthalocyanine chloride (AlPcCl), Aluminum phthalocyanine hydroxide (AlPcOH) and zinc phthalocyanine (PcZn) were tested in the presence (matte red LED, potency of 2.5-2.3 μW for 30 min) and absence of light ...
V, Nesi-Reis +9 more
openaire +2 more sources
L. amazonensis ARG remains compartmentalized during macrophage in vitro infection.
, 2012 Cytological preparation probed for arginase immunolocalization via electron microscopy. (A) J774A 1 macrophages infected for 24 hours with L. amazonensis promastigotes in the stationary phase (4 different sections). (B) L.
Stephen M. Beverley (174720) +4 more
core +1 more source
Fusion between Leishmania amazonensis and Leishmania major parasitophorous vacuoles: live imaging of coinfected macrophages. [PDF]
PLoS Neglected Tropical Diseases, 2010 Protozoan parasites of the genus Leishmania alternate between flagellated, elongated extracellular promastigotes found in insect vectors, and round-shaped amastigotes enclosed in phagolysosome-like Parasitophorous Vacuoles (PVs) of infected mammalian ...
Fernando Real +2 more
doaj +1 more source
ChemMedChem, Volume 21, Issue 16, 27 August 2026.A novel pyridine–thiazole derivative, Compound 8, exhibited potent dual antitrypanosomatid activity. It demonstrated remarkable in vitro efficacy against Trypanosoma cruzi (IC50 = 1.0 µM) and L. amazonensis (IC50 = 3.9 µM). Molecular docking studies suggested interactions with heme and multiple molecular targets.
Anderson José Firmino Santos da Silva +10 more
wiley +1 more source