Results 31 to 40 of about 2,614 (160)

Disk Galaxies Are Self-similar: The Universality of the H i-to-Halo Mass Ratio for Isolated Disks

The Astrophysical Journal Letters, 2023
Observed scaling relations in galaxies between baryons and dark matter global properties are key to shed light on the process of galaxy formation and on the nature of dark matter.
Marie Korsaga, Benoit Famaey, Jonathan Freundlich, Lorenzo Posti, Rodrigo Ibata, Christian Boily, Katarina Kraljic, D. Esparza-Arredondo, C. Ramos Almeida, Jean Koulidiati   +9 more
doaj   +1 more source

cdc-Like/Dual-Specificity Tyrosine Phosphorylation–Regulated Kinases Inhibitor Leucettine L41 Induces mTOR-Dependent Autophagy: Implication for Alzheimer’s Disease [PDF]

Molecular Pharmacology, 2014
Leucettines, a family of pharmacological inhibitors of dual-specificity tyrosine phosphorylation regulated kinases and cdc-like kinases (CLKs), are currently under investigation for their potential therapeutic application to Down syndrome and Alzheimer's disease.
Fant, Xavier, Durieu, Emilie, Chicanne, Gaëtan, Payrastre, Bernard, Sbrissa, Diego, Shisheva, Assia, Limanton, Emmanuelle, Carreaux, François, Bazureau, Jean-Pierre, Meijer, Laurent   +9 more
openaire   +2 more sources

Identification of Mutations in Protein Kinase CKIIβ Subunit That Affect Its Binding to Ribosomal Protein L41 and Homodimerization

BMB Reports, 2003
Protein kinase CKII is composed of two catalytic (alpha or alpha') subunits and two regulatory (beta) subunits. The CKIIbeta subunit is thought to mediate the tetramer formation and interact with other target proteins. However, its physiological function remains obscure.
Bong-Hyun, Ahn, Ji-Hoon, Lee, Young-Seuk, Bae   +2 more
openaire   +3 more sources

Heterobeltiosis and interrelationship of some of important quantitative traits in oilseed rape genotypes

Open Agriculture, 2019
Half diallel crosses of eight spring genotypes of oilseed rape (Brassica napus L.) were considered to evaluate heterobeltiosis effects of plant height, yield component characters, seed yield and harvest index.
Rameeh Valiollah
doaj   +1 more source

Inducible expression of a gene encoding an L41 ribosomal protein responsible for the cycloheximide-resistant phenotype in the yeast Candida maltosa

Journal of Bacteriology, 1995
In a previous paper (S. Kawai, S. Murao, M. Mochizuki, I. Shibuya, K. Yano, and M. Takagi, J. Bacteriol. 174:254-262, 1992), we showed that in each genome of several yeast species, there is one of two types of L41 gene, one for an L41 (Q-type) protein which confers cycloheximide (CYH) resistance or one for an L41 (P-type) protein which does not.
E, Mutoh, M, Mochizuki, A, Ohta, M, Takagi   +3 more
openaire   +3 more sources

Prosocial CEOs and Accounting Manipulation Le comportement prosocial des PDG et la manipulation comptable

Contemporary Accounting Research, EarlyView.
ABSTRACT This paper examines the association between CEOs' prosocial tendency and their firms' likelihood of accounting manipulation. We measure CEOs' prosocial tendency based on their involvement with charitable organizations. We find that prosocial CEOs are less likely to engage in accounting manipulation, as proxied by material non‐reliance ...
Mei Feng, Weili Ge, Zhejia Ling, Wei Ting Loh   +3 more
wiley   +1 more source

Design and Synthesis of Thiazolo[5,4-f]quinazolines as DYRK1A Inhibitors, Part II

Molecules, 2014
The convenient synthesis of a focused library (forty molecules) of novel 6,6,5-tricyclic thiazolo[5,4-f]quinazolines was realized mainly under microwave irradiation.
Alicia Foucourt, Damien Hédou, Carole Dubouilh-Benard, Angélique Girard, Thierry Taverne, Anne-Sophie Casagrande, Laurent Désiré, Bertrand Leblond, Thierry Besson   +8 more
doaj   +1 more source

The Experience of Care in People With Palliative Needs and Their Families: A Qualitative Metasynthesis

Journal of Clinical Nursing, EarlyView.
ABSTRACT Aim To synthesise and reinterpret qualitative evidence on how people with palliative care needs and their family caregivers experience the care process. Background Palliative care aims to provide holistic, person‐ and family‐centred care.
Ana Gil Méndez, Caterina Checa Jiménez, Ingrid Bullich Marín, Laura Navarrete Reyes, Carolina Watson Badia, Nina Granel Gimenez, Lídia Ribera Barberan, Mireia Subirana Casacuberta, Juan M. Leyva‐Moral   +8 more
wiley   +1 more source

Integrative Insights Into DYRK1A From Molecular Function to Therapeutic Advancement

Chemical Biology &Drug Design, Volume 108, Issue 1, July 2026.
At the center the 3D structure of DYRK1A has been displayed. The dual‐function of DYRK1A involved in cancer and neurodegeneration, i.e., its overexpression drives Down syndrome, neurodegenerative disease etc., and underexpression causes intellectual disability, seizures, etc.
Sampriti Paul, Sonal Dubey, Prashant Tiwari   +2 more
wiley   +1 more source

Comparative genomic analysis of Myroides odoratimimus isolates

MicrobiologyOpen, 2019
Myroides odoratimimus is an important nosocomial pathogen. Management of M. odoratimimus infection is difficult owing to the multidrug resistance and the unknown pathogenesis mechanisms. Based on our previous genomic sequencing data of M.
Shaohua Hu, Lin Cao, Yiyin Wu, Yajun Zhou, Tao Jiang, Liqiang Wang, Qiujing Wang, Desong Ming, Shicheng Chen, Mingxi Wang   +9 more
doaj   +1 more source