Results 111 to 120 of about 108,590 (313)

Erucic Acid, Derived by Lactobacillus Crispatus, Induces Ferroptosis in Cervical Cancer Organoids Through the PPAR‐δ Signaling Pathway

Advanced Science, EarlyView.
Utilizing PDO, cell lines and cervical cancer xenograft (CDX) models, the study demonstrate both in vitro and in vivo that the metabolite of L. crispatus, erucic acid, can modulate the proliferation, migration and invasion of cervical cancer by activating the PPAR‐δ pathway.
Qianwei Zhen, Yuexuan Xu, Ying Xu, Xiao Liu, Yuting Zhang, Dan Ye, Sai Han, Shili Liu, Youzhong Zhang   +8 more
wiley   +1 more source

The reduction of quinic acid to dihydroshikimic acid by certain lactic acid bacteria [PDF]

, 1957
J. G. Carr, Abiola M. Pollard, G. C. Whiting, A. H. Williams   +3 more
openalex   +1 more source

An Engineered Probiotic Consortium Based on Quorum‐Sensing for Colorectal Cancer Immunotherapy

Advanced Science, EarlyView.
This work develops an engineered probiotic consortium sensing pH, hypoxia, and lactate in the tumor microenvironment. It releases a lactate‐depleting enzyme (LdhA) and a PD‐L1 nanobody. In humanized mouse models (MC38 and HT‐29 tumors), it achieves durable oscillations, suppresses tumors, activates CD8+, CD4+, IFN‐γ+ T cells, and reduces Foxp3 ...
Yufei Guo, Mengxue Gao, Lina Wang, Haibin Yuan, Jianan Yin, Jiahao Wu, Xinran Gao, Zhixin Zhu, Yan Zhang, Zichen Wang, He Huang, Guangbo Kang   +11 more
wiley   +1 more source

ANTAGONISM OF AMINO ACIDS IN THE GROWTH OF LACTIC ACID BACTERIA

, 1948
W.L. Brickson, L.M. Henderson, I. Solhjell, C.A. Elvehjem   +3 more
openalex   +1 more source

Vitamin and Nitrogenous Food Requirements of the True Lactic Acid Bacteria [PDF]

, 1935
S. Orla-Jensen
openalex   +1 more source

A Dual‐Target Recognition System Based on Acid‐Degradable Ni‐MOF and Aptamer Guidance for Precise Tumor Diagnosis and Combined Therapy

Advanced Science, EarlyView.
This work reports a Ni‐doped ZIF‐8 nanoplatform co‐encapsulating glucose oxidase and horseradish peroxidase, enabling a cascade catalytic reaction that produces hydroxyl radicals from endogenous glucose and hydrogen peroxide. Upon near‐infrared irradiation, the system simultaneously achieves photothermal and chemodynamic therapy, offering an effective ...
Jing Xu, Hanxiao Chen, Yifang Tao, Hong Wang, Zhenlong Wang, Yuquan Xue, Delai Fu, Huan Pang, Li Xue   +8 more
wiley   +1 more source

DEPENDENCE OF THE TOXICITY OF CATIONS FOR LACTIC ACID BACTERIA ON pH AND INCUBATION TIME [PDF]

, 1954
Robert A. MacLeod
openalex   +1 more source

The High‐Altitude Adaptation Characteristics of Microbiota‐Host Cross‐Talk in Yak Gastrointestinal Track

Advanced Science, EarlyView.
In this study, a single‐cell atlas of 117,019 yak gastrointestinal cells across 54 subtypes identified HNF4A and SREBF2 as key transcription factors targeting MYO6 gene. Cross‐species and multi‐omics analyses reveals epithelial cells as key regulators that, through interactions with microbes, particularly Bacillus, facilitate flexible energy supply and
Chun Huang, Minghao Zhang, Qingbo Zheng, Qinran Yu, Guowu Yang, Wenwen Ren, Xiaoming Ma, Yongfu La, Pengjia Bao, Min Chu, Xian Guo, Chunnian Liang, Ping Yan   +12 more
wiley   +1 more source

On the Pentose-fermenting Lactic Acid Bacteria

, 1940
Mamoru Iwasaki
openalex   +2 more sources

Medicago Sativa L. Saponin‐Driven Lactobacillus Intestinalis Restores Intestinal Stemness in Naturally Aged Mice via the Bile Acid‐FXR‐Wnt Signaling Axis

Advanced Science, EarlyView.
This study examines the mechanism by which alfalfa saponin (AS) regulates intestinal stemness via modulation of the gut microbiota. The results indicate that AS significantly increases the abundance of Lactobacillus intestinalis, which subsequently activates Wnt signaling via bile acid metabolism and enhances intestinal stemness. These findings provide
Mengqi Liu, Jiamin Sun, Zuyang Jia, Yalei Cui, Xiaoyan Zhu, Zhichang Wang, Hao Sun, Boshuai Liu, Yinghua Shi   +8 more
wiley   +1 more source