Results 31 to 40 of about 4,156 (155)

Brain accumulation of lactosylceramide characterizes GALC deficiency in a zebrafish model of Krabbe disease. [PDF]

Brain
: Krabbe disease (KD) is an autosomal recessive sphingolipidosis due to mutations of the GALC gene encoding for the lysosomal β-galactosylceramidase (GALC) that removes β-galactose from β-galactosylceramide, β-lactosylceramide (LacCer), and the ...
Guerra J, Belleri M, Scalvini E, Capoferri D, Tobia C, Ravelli C, Corli M, Bresciani N, Casas J, Fabrias G, Dei Cas M, Presta M, Mignani L.   +12 more
europepmc   +2 more sources

Synaptobrevin-2 Containing Extracellular Vesicles Are Rapidly Incorporated Into Mammalian Neurons via a Dynamin-Dependent Pathway. [PDF]

J Neurochem
In this article, Hannett and colleagues investigate extracellular vesicles (EVs) secreted by neurons, small membrane‐bound organelles that transmit information among cells. They found that EVs are mainly uptaken by target neurons via a mechanism dependent on the membrane scission protein Dynamin.
Hannett V, Vilcaes AA, Hugelier S, Tang Q, Lakadamyali M, Chanaday NL.   +5 more
europepmc   +2 more sources

Glycosphingolipid levels in an unusual neurovisceral storage disease characterized by lactosylceramide galactosyl hydrolase deficiency: lactosylceramidosis

Journal of Lipid Research, 1972
The glycosphingolipid composition of brain and visceral tissue from a patient with an unusual neurovisceral lipid storage disease, characterized by a lactosylceramide galactosyl hydrolase deficiency, was determined. Analyses of erythrocytes, plasma, bone
Glyn Dawson
doaj   +1 more source

A Patient With Encephalomyeloradiculoneuropathy Exhibiting a Relapsing–Remitting Clinical Course: Correlation of Serum and Cerebrospinal Fluid Anti-Neutral Glycosphingolipids Antibodies With Clinical Relapse

Frontiers in Neurology, 2018
Several patients who had a progressive clinical course involving both the central and peripheral nervous systems have been reported, but the diagnostic marker has been remained uncertain.
Hitoki Nanaura, Hiroshi Kataoka, Sayuri Shima, Naoki Iwasa, Nobuyuki Eura, Kazuma Sugie, Tatsuro Mutoh, Satoshi Ueno   +7 more
doaj   +1 more source

Glycosphingolipids from cultured astroblasts

Journal of Lipid Research, 1977
The glycolipids of two clonal lines astroblasts, NN clone and C6 clone, were studied. Glucosylceramide and lactosylceramide were present at very low levels in both clones, but the most common myelin glycolipids galactosylceramide and sulfatide, were not ...
J Robert, G Rebel, P Mandel
doaj   +1 more source

Quantitative analysis of plasma neutral glycosphingolipids by high performance liquid chromatography of their perbenzoyl derivatives

Journal of Lipid Research, 1977
A quantitative high performance liquid chromatography method for the analysis of neutral glycosylceramides as their perbenzoyl derivatives has been devised.
M D Ullman, R H McCluer
doaj   +1 more source

Enriching plausible new hypothesis generation in PubMed. [PDF]

PLoS ONE, 2017
Most of earlier studies in the field of literature-based discovery have adopted Swanson's ABC model that links pieces of knowledge entailed in disjoint literatures.
Seung Han Baek, Dahee Lee, Minjoo Kim, Jong Ho Lee, Min Song   +4 more
doaj   +1 more source

Direct interaction, instrumental for signaling processes, between LacCer and Lyn in the lipid rafts of neutrophil-like cells

Journal of Lipid Research, 2015
Lactosylceramide [LacCer; β-Gal-(1-4)-β-Glc-(1-1)-Cer] has been shown to contain very long fatty acids that specifically modulate neutrophil properties. The interactions between LacCer and proteins and their role in cell signaling processes were assessed
Elena Chiricozzi, Maria Grazia Ciampa, Giuseppina Brasile, Federica Compostella, Alessandro Prinetti, Hitoshi Nakayama, Roudy C. Ekyalongo, Kazuhisa Iwabuchi, Sandro Sonnino, Laura Mauri   +9 more
doaj   +1 more source

Neutral glycolipids in leukemic and nonleukemic leukocytes

Journal of Lipid Research, 1971
Neutral lipids, free and total cholesterol, glycolipids, and phospholipids were determined in 20 preparations of leukocytes distributed in four groups.
J. HILDEBRAND, P. STRYCKMANS, P. STOFFYN
doaj   +1 more source

Glycosphingolipids Recognized by Acinetobacter baumannii

Microorganisms, 2020
Acinetobacter baumannii is an opportunistic bacterial pathogen associated with hospital-acquired infections, including pneumonia, meningitis, bacteremia, urinary tract infection, and wound infections.
Miralda Madar Johansson, Mehjar Azzouz, Beatrice Häggendal, Karin Säljö, Henri Malmi, Anton Zavialov, Susann Teneberg   +6 more
doaj   +1 more source