Results 91 to 100 of about 7,574 (306)

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

Numerical Investigation on the Effect of Avenue Trees on PM2.5 Dispersion in Urban Street Canyons

Atmosphere, 2017
The Reynolds-averaged Navier-Stokes (RANS) model and revised generalized drift flux model were used to investigate the characteristics of airflow fields and PM2.5 dispersion in street canyons with a variety setting on tree crown morphologies (i.e ...
Bo Hong, Borong Lin, Hongqiao Qin
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Estudio genético funcional de la interacción de las cinasas GacS y LadS en Azotobacter vinelandii [PDF]

, 2020
"En este trabajo, se generó una doble mutante gacSladS. La doble mutación ladSgacS generó una disminución considerable en la síntesis de alginato y en la expresión de rsmz1, rsmz2 y rsmY a niveles de la mutante sencilla gacS. Los resultados obtenidos nos
Acocal González, Verónica
core  

التغذية الراجعة بلوحة معلومات تحليلات التعلم في بيئة تعلم ذكية (رؤية نظرية وتحديات أخلاقية) [PDF]

تکنولوجیا التعلیم: سلسلة دراسات و بحوث
تتناول هذه الورقة الاستخدام المتنامي للوحة معلومات تحليلات التعلم (LADs) في بيئات التعلم الذكية، مسلطة الضوء على دورها في دعم عملية التعلم وتحسين مخرجاتها من خلال تقديم بيانات مرئية وتحليلية تساهم في تعزيز فهم المتعلمين والمعلمين لسير العملية التعليمية ...
وليد يوسف محمد, حنان حسين قرنى, وائل رمضان عبد الحميد, منى محمود محمد   +3 more
doaj   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Where are the lads of New Zealand tonight? [PDF]

, 1914
Sheet music of R.P. Weston, P.C. Cole and Hermann E. Darewski's 'Where are the Lads of New Zealand tonight?
Weston, R. P (Robert P.), 1878-1936., Cole, P. C., Darewski, Herman, 1883-1947.   +2 more
core  

Lateral decubitus strategy (LADS) is superior to ventilatory strategy (VESPA) in preventing atelectasis from obscuring targets during robotic bronchoscopy, leading to improved procedural outcomes (LADS vs VESPA trial) [PDF]

Background: Atelectasis during peripheral bronchoscopy can cause CT-to body divergence, false positive radial-probe endobronchial ultrasound images, and can obscure a target.
Eapen, George A, Song, Juhee, Grosu, Horiana B, Armas Villalba, Aristides J, Ost, David E, Goertzen, Mike, Lin, Julie, Boster, Joshua M, Bandari, Bharat S, Casal, Roberto F, Chintalapani, Gouthami, Sarkiss, Mona, Jimenez, Carlos A, Sabath, Bruce F   +13 more
core   +1 more source

The Reluctant Patriarch: The Emergence of Lads and Lad Mags in the 1990s [PDF]

InMedia, 2012
This paper examines the representation of the ‘weak man’ (or ‘useless bloke’) in contemporary popular British culture, most visibly in television comedy, but also apparent in men’s magazines such as FHM and Loaded, in popular ‘confessional’ novels of the genre inaugurated by Nick Hornby, and even noted in theatre and popular science writing. While many
openaire   +1 more source